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In recent years, research into cannabis and its main psychoactive ingredient, Δ⁹-tetrahydrocannabinol (THC), has unearthed medical benefits including anti-inflammatory and neuroprotective properties.

This study mapped how EPA and DHA are distributed across lipid classes in microalgae, fish, krill, and commercial omega-3 supplements using lipid-class–resolved analysis. It shows that lipid structure, not just total omega-3 content, differs markedly across sources and may influence their nutritional relevance.

This cross-sectional analysis of 8,320 Brazilian adults quantified melatonin intake from habitual diets and examined associations with multiple chronic health outcomes. Higher dietary melatonin intake was inversely associated with obesity and depression in a non-linear pattern, with no significant associations observed for other conditions.

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and environmental exposures shape the human immune system through distinct DNA methylation mechanisms. Genetic effects concentrate within gene bodies of memory cells, while environmental exposures primarily remodel regulatory regions in naive immune cells.

This cross-sectional study of 300 school-aged girls in Tehran found that higher air pollution exposure was consistently associated with poorer concentration, while dietary antioxidant capacity showed weaker, model-dependent links to attention. No significant associations or interactions were observed for short-term memory, highlighting pollution exposure as the dominant factor influencing attentional performance.

Researchers modelled future injury risk in male professional footballers across seven European leagues and linked this risk to market valuation using a two-stage econometric approach. A higher predicted probability of severe or recurrent injury was associated with a substantial reduction in players’ market value.

Lifetime alcohol intake, not just recent drinking, is associated with colorectal cancer risk in older adults followed in the PLCO Cancer Screening Trial. Heavy and consistent long-term drinking was linked to higher colorectal cancer risk, while alcohol cessation was associated with lower odds of early, nonadvanced adenomas.

UVA Health scientists are reporting promising success as they pioneer a new way to create vaccines far more quickly, nimbly and inexpensively than ever before.

The tiny zebrafish is helping researchers rapidly determine whether a newborn's genetic mutation is likely to cause spinal muscular atrophy (SMA), one of the leading causes of infant mortality worldwide.