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This review argues that women’s higher Alzheimer disease risk may be shaped in part by midlife neuroendocrine aging, especially the menopause transition, rather than by longevity alone. It highlights early menopause, bilateral oophorectomy, vasomotor symptoms, and midlife cognitive changes as underinvestigated but potentially important risk markers, while calling for sex-specific, biomarker-driven prevention strategies.

The Nanomedicine and Nanotoxicology Group (GNano) at the University of São Paulo's São Carlos Institute of Physics (IFSC-USP) in Brazil has discovered a way to transform hydroxyapatite, a bioceramic material, into a nanoparticle with enhanced intrinsic luminescence.

Childhood obesity may be quietly undermining one of the central promises of American life.

Having type 1 diabetes is associated with a higher risk of developing dementia, according to a study published March 18, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

A team of scientists at Henry Ford Health + Michigan State University Health Sciences have uncovered a mechanism that allows certain head and neck cancers to hide from the immune system, a discovery that could change how some of the most treatment resistant tumors are approached.

Researchers at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Tisch Cancer Center have discovered a biological pathway that helps explain why some bladder cancers do not respond well to immunotherapy.

Worse financial well-being in midlife and older age -and especially declines over time-are associated with lower memory scores and faster cognitive decline, reports a new study at Columbia University Mailman School of Public Health.

A large-scale genetic analysis of East Asian individuals led by Fuu-Jen Tsai of the China Medical University Hospital, finds that people with greater height face a higher risk of endometriosis and atrial fibrillation.

A research group led by Professor Cecilia Sahlgren at Åbo Akademi University (Finland) and the InFLAMES Research Flagship has identified a new mechanism directing the adverse remodeling of tumor tissue during breast cancer progression.

Treatments that target a fragment of the mutant protein that causes Huntington's disease might be more effective than treatments, now in clinical trials, that target the whole protein but leave this fragment intact, a new study in mice suggests.

Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular benefits.

A new study found that precise application of radio waves can change the activity of brain cells in ways that could counter neurological conditions.

Researchers discovered an antioxidant, glutathione, that cancer cells appear to be "addicted to" as fuel, opening new pathways for investigation and a potential drug that can restrict the way tumors use this nutrient.

A prospective analysis of 6,531 adults in the multiethnic MESA cohort found that higher ultraprocessed food intake was associated with a graded increase in incident ASCVD risk, with each additional daily serving linked to about a 5% higher risk. The association was stronger in Black participants, while no significant interaction was seen by sex or income.

Researchers used five prospective cohorts from the US and China to identify circulating gut microbiota-related metabolites linked to future coronary heart disease, then tested the findings through discovery, in silico validation, and targeted quantitative validation. The study ultimately highlighted nine metabolites associated with incident CHD, supporting a potential role for microbial metabolism in heart disease risk while not proving causation

Researchers found that GLP-1 medicines caused weight loss mainly through fat reduction, with only modest decreases in absolute muscle mass and no disproportionate loss of muscle function. In mice, physical performance improved, while in a small 12-week human pilot trial, strength was preserved despite reduced thigh muscle size.

For more than a century, heparin has been the go-to anticoagulant to prevent harmful blood clots in blood vessels or the heart from forming or getting larger.

Young children who attend nursery get sick more often than those who don't, but they will go on to have fewer illnesses during early school years, finds a new review of evidence by a group of parent-scientists involving University College London (UCL) researchers.

A protein already targeted by FDA-approved cancer drugs may also help the body fight influenza, according to new research from The Jackson Laboratory (JAX).

To reduce the adverse health effects associated with exposure to second-hand smoke, Japan fully enforced the Revised Health Promotion Law in April 2020, introducing a nationwide indoor smoking ban in restaurants and similar hospitality establishments.