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Lysosomal storage of drugs may influence cancer treatment outcomes
One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others.
Continuous Medicaid coverage lowered postpartum uninsurance, but disparities remain
Postpartum uninsurance declined among Black women in non-expansion states during the COVID-19 continuous Medicaid coverage policy, but racial gaps persisted, according to a new study at Columbia University Mailman School of Public Health.
Breakfast, exercise, and sleep linked to better mental resilience
Do you ever feel mentally stuck, like you can't cope when a stressful situation hits? A healthy breakfast, exercise, and a good night's sleep might be just what you need to build psychological flexibility, and new research from Binghamton University shows why that matters.
Study reveals new dual role of ezrin in osteosarcoma
Scientists at Georgetown University's Lombardi Comprehensive Cancer Center have uncovered a new dual function for a well-known cancer-related protein called ezrin.
Engineered bacteria may improve precision cancer drug delivery
Every year, millions of people are diagnosed with cancer globally; however, current treatments are limited by disease complexity.
Gut microbe molecules linked to coronary heart disease risk
In a study involving data from thousands of people, the risk of a new coronary heart disease diagnosis was statistically associated with bloodstream levels of nine specific molecules that are produced by gut microbes.
Anti-aging drug combination causes brain damage in mice
A two-drug combination frequently used in anti-aging research causes brain damage in mice, University of Connecticut researchers report in the March 16 issue of PNAS.
Blocking fructose metabolism may improve brain tumor immunotherapy response
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune responses and promote tumor growth, reports a study published on March 17 in the Proceedings of the National Academy of Sciences.
Belly fat linked to heart failure risk through inflammation
New research suggests that measures of excess weight around the waist (central obesity or visceral fat) may increase the risk of heart failure primarily due to inflammation, according to findings presented at the American Heart Association's EPI|Lifestyle Scientific Sessions 2026.
Study identifies risk factors for readmissions after shoulder replacement surgeries
Shoulder replacement is the third most common joint-replacement surgery in the U.S. and is likely to become more common as the population ages, according to Penn State researchers.
How one antibiotic dose can reshape your gut microbiome for years
Long-term registry-linked analysis of nearly 15,000 adults shows that antibiotic use is associated with persistent changes in gut microbiome diversity and composition for up to 4–8 years. These effects vary by antibiotic class, with clindamycin, fluoroquinolones, and flucloxacillin showing the strongest and most sustained associations.
Yogurt, cheese, and chocolate consumption is tied to reduced mortality risk, researchers report
A large meta-analysis of 50 cohort studies involving over three million adults found that higher consumption of certain fermented foods is associated with lower risks of all-cause and cardiovascular mortality. Fermented milk products also showed inverse associations with cancer mortality, while other foods like miso and bread showed no consistent effects.
Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria
Researchers engineered a two-strain microbial system that converts PET-derived terephthalic acid into levodopa, overcoming key bottlenecks in transport and enzyme inhibition. The proof-of-concept process achieves high yields under mild conditions and demonstrates a potential route for upcycling plastic waste into valuable pharmaceuticals.
Researchers show how smartwatches can help identify insulin resistance
Researchers developed a scalable framework that predicts insulin resistance using wearable-device signals, routine blood biomarkers, and demographic data, with stronger performance when these data streams were combined. The study also introduced an AI agent to explain insulin resistance risk, interpret results, and support earlier metabolic risk screening.
Study uncovers how tuberculosis bacteria fuel themselves during infection
Researchers at The Hospital for Sick Children (SickKids) have uncovered how the bacteria that causes tuberculosis fuels itself during infection, providing new insights into one of the world's deadliest infectious diseases.
New CAR-T cell therapy shows promise for treating osteosarcoma
Finding an effective treatment for osteosarcoma, the most common type of bone cancer in children and young adults, has puzzled medical researchers for 40 years.
Early-life PFAS exposure may hinder adolescent bone development
Early-life exposure to per- and polyfluoroalkyl substances (PFAS) may influence how children's bones develop during adolescence, according to new research published in the Journal of the Endocrine Society.
Activating hypoxia signaling improves metabolism and bone health
Obesity is widely known for increasing the risk of diabetes and cardiovascular disease, but its damaging effects on the skeleton are often overlooked. Excess body fat can disrupt bone metabolism, weaken bone quality, and impair fracture repair.
Blood pressure readings may help identify future dementia risk
Measures of blood vessel health derived from routine blood pressure readings may help identify adults at increased risk for dementia, according to research being presented at the American College of Cardiology's Annual Scientific Session (ACC.26).
Ultra-processed food consumption associated with increased risk for heart disease
People who consumed over nine servings of ultra-processed foods per day on average were 67% more likely to suffer a major cardiac event than people consuming about one serving of such foods per day, in a study being presented at the American College of Cardiology's Annual Scientific Session (ACC.26).




