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Missing doses of antihypertensive medication erase life-saving cardiovascular benefits
The true impact of missing doses of blood pressure-lowering medication will be demonstrated in a presentation at ESC Congress 2026.
New mutant rat model replicates human chronic kidney disease
Chronic kidney disease (CKD) is a major health burden affecting approximately one in ten adults globally. Even with improved treatments, many patients continue to have worsening loss of kidney function, resulting in the need for dialysis or transplantation.
Multi-ancestry genetic score improves risk prediction for Alzheimer's disease
Late-onset Alzheimer disease (AD) is a progressive disorder characterized by cognitive decline and memory impairment, affecting an estimated 6.9 million people in the U.S.
Post-seizure psychotic episodes linked to future mental health risks
Some people with epilepsy experience delusions, hallucinations, paranoia and confusion after a seizure.
Study challenges traditional breast cancer classification methods
Breast cancer is often classified as either estrogen receptor-positive (hormone-sensitive) or not. However, a new study from Karolinska Institutet suggests that this simplified classification may overlook important biological differences between patients that could affect treatment decisions.
Overuse of short-acting bronchodilator linked to increased risk of cardiovascular diseases and death
Overuse of reliever inhalers is associated with higher risks of developing and dying from cardiovascular disease, including heart failure, heart attack and ischemic stroke, in asthma and COPD patients, according to a study published today in ERJ Open Research.
Extreme heat exposure triggers broad range of medical emergencies
When temperatures spike, emergency physicians expect to see more cases of dehydration and heat stroke.
New funding backs pioneering research to make brain cancer treatment more effective
Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more effective against tumors, while reducing damage to healthy tissue.
Brain shrinkage biomarker may predict early-onset Alzheimer’s progression
In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment (MCI) to dementia, according to a new study published August 26, 2026, in Neurology, an official journal of the American Academy of Neurology.
UofL receives new federal funding to advance metabolic health research
Chronic health conditions such as diabetes, obesity, heart disease and metabolic liver disease have sharply increased in recent decades and are among the most urgent health challenges facing our society.
Brain atrophy on MRI could help predict Alzheimer’s progression
Mass General Brigham Neuroscience Institute researchers have found that a pattern of brain atrophy visible on MRI could help predict how quickly people with early-onset Alzheimer's disease progress from mild cognitive impairment to dementia.
Can caffeine make you mentally sharper in the morning? This study tested the idea
In a controlled crossover study of 51 recreationally active young men with low habitual caffeine intake, researchers tested whether 300 mg of caffeine taken about an hour before morning testing affected cognition, mood, temperature, appetite, and related outcomes, with reactive agility assessed in 27 participants. Caffeine did not improve cognitive or reactive agility performance or meaningfully alter mood, tiredness, appetite, or thermoregulation under the study conditions.
Monod Bio licenses AI-designed protein technologies to SignalChem Biotech for custom discovery assays
Monod Bio, a Seattle-based AI-enabled protein design company, and SignalChem Biotech Inc., a wholly-owned subsidiary of Sino Biological, Inc., today announced a non-exclusive licensing agreement covering Monod Bio’s proprietary LuxSit de novo luciferase technology and NovoBodies.
Study reveals why diffuse midline glioma develops in brain midline regions
Scientists at St. Jude Children's Research Hospital have shown that specific brain cells respond differently to the H3.3 K27M, a mutation in the histone H3.3 protein that drives many cases of diffuse midline glioma (DMG), depending on the cell's location in the developing brain.
Gut microbiome atlas maps how bacteria establish themselves and shift in inflammatory bowel disease
Researchers created a microbiome-wide atlas mapping more than seven million colonization factor genes across 4,716 human gut microbial species, revealing three putative strategies linked to metabolism, stress resistance, and microbial communication. Applying the framework to inflammatory bowel disease showed that colonization-factor profiles can provide a compact, biologically interpretable view of disease-associated microbiome changes.
Faulty myelin-making brain cells may help drive cognitive decline with age
Researchers found that greater age-related cognitive decline was associated with more dysfunctional oligodendrocytes, reduced NRF2 expression, smaller myelinated axons, and abnormally thicker myelin in human white matter. Experiments in mice showed that deleting NRF2 specifically from oligodendrocytes reproduced key white matter abnormalities and reduced cognitive improvement over time, implicating this pathway in cognitive aging.
A major NFL brain study puts new numbers on the burden of CTE
Researchers analyzed 1,712 former NFL players who died between 2008 and 2021, including 338 brain donors, to estimate the possible prevalence of chronic traumatic encephalopathy (CTE) at death and its association with dementia. At least 24.5% of players who died from 2016 to 2021 had confirmed CTE, while stage IV CTE among brain donors was associated with a 44% higher risk of clinician-adjudicated dementia.
Men see traditional dieting as restrictive and female-focused, study finds
A new study has identified why many men struggle with weight loss, finding that traditional diet programmes are often perceived as too restrictive and primarily aimed at women.
New retina model reveals how CLN3-Batten disease damages vision
Researchers have developed a new way to study CLN3-Batten disease, a rare, inherited condition that causes early vision loss in children followed by progressive neurological decline.
Maternal immune response to urinary tract infection may drive preterm birth risk
A new study published in Science Translational Medicine shows that the increased risk of preterm pregnancies associated with urinary tract infection (UTI), is linked to the body's immune response to the infection rather than to the bacteria themselves.




