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A multinational Nature Medicine validation study found that PREVENT and SCORE2 cardiovascular risk equations performed generally well across 6.4 million people from observational cohorts and randomized trials. The findings support broader use of these tools for CVD risk stratification, while highlighting the need for local calibration and more validation in underrepresented regions.

A BMJ systematic review of 59 human studies found no evidence supporting causal links between aluminum-adjuvanted vaccines and serious or long-term outcomes such as autism spectrum disorder, asthma, autoimmune conditions, or other chronic illnesses. The most consistent adverse events were uncommon, local, self-limited persistent nodules or granulomas, likely reflecting delayed-type hypersensitivity.

Ontario physicians increased their workload in the first two trimesters of pregnancy, suggesting many may frontload clinical work before parental leave. Parental leave varied widely by specialty, with surgeons returning earliest and psychiatrists returning latest, highlighting persistent inequities in how medical practice supports childbearing physicians.

Older Australians who reduce either dietary fat or animal-based protein show signs of reduced biological age, new research from the University of Sydney shows.

Whether people are mulling over the pros and cons of a purchase or assessing their interactions with new people, they may show a bias in placing more value on perceived positive or negative information.

We are all born completely helpless, with little of the knowledge and skills we will need to survive as adults. Even our ability to communicate is almost entirely learned from our parents or caregivers.

While they share similar depressive and cognitive symptoms, the biological underpinnings of bipolar disorder and major depressive disorder are distinct.

Infants exposed to certain environmental chemicals, including breast milk and everyday products such as personal care items, are more likely to have lower bone density in the first year of their lives, according to research presented at the 28th European Congress of Endocrinology in Prague.

Partners of women with gestational diabetes have more health-related risk factors and morbidity than partners of women without gestational diabetes.

New UCLA-led research finds that use of telemedicine has not significantly increased visits and medical spending across all payer types.

Among young adults with kidney failure, the expansion of Medicaid following the Affordable Care Act signed into law in 2010 was associated with substantial declines in one-year death rates, researchers from Brown University found in a new study.

Type 2 diabetes affects millions of people worldwide and now a new international study, jointly led by Adelaide University, University of Oxford, ETH Zurich, and Stanford University, has found one in ten people may not be benefiting from common medications used to treat the condition.

Stenotrophomonas maltophilia (S. maltophilia) is a multidrug-resistant bacterium that can cause severe and life-threatening hemorrhagic pneumonia in individuals with weakened immune systems.

Qureight, an end-to-end imaging CRO that provides enterprise-grade imaging and precision endpoints for clinical trials with a focus on lung and heart disease, today announced it has established a Scientific Advisory Board (SAB) focused on pulmonary hypertension (PH).

Scientists at the University of East Anglia (UK) have contributed to discovering a "control switch" inside our immune cells that helps the body destroy dangerous fungal infections.

A fluid that women with advanced ovarian cancer know all too well - ascites, the buildup of liquid in the belly - may be doing more than causing discomfort.

Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily dose of antiretroviral drugs.

A new study by the Garvan Institute of Medical Research has uncovered a hidden mechanism explaining why breast cancer can return many years after successful treatment.

Findings indicate that elevated fine PM exposure before surgery correlates with higher postoperative complication rates, urging further research in this area.

The European Society of Cardiology identifies ultra-processed foods as a key cardiovascular risk, urging a shift in dietary guidelines for better heart health.