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Negative behavioral effects of psilocybin persist in mouse mothers and offspring
Magic mushrooms may not be the answer to postpartum depression, new research from the University of California, Davis suggests.
Income inequality in society associated with structural changes in the developing brain
Income inequality in society has been linked to structural changes in the brains of children who go on to experience poorer mental health.
Discovery of EUDAL reveals new mechanism behind chemotherapy resistance in oral cancer
Oral cancer is one of the most common head and neck cancers worldwide, with hundreds of thousands of new cases diagnosed every year. Despite advances in surgery, radiotherapy, and chemotherapy, survival rates remain poor.
Tagomics publishes a new approach to genome-wide epigenomic profiling
Tagomics Ltd., a pioneering biomarker discovery and diagnostics company, today announced the publication of a peer-reviewed study in Cell Reports Methods, underpinning its epigenomic profiling technology, Active-Seq, the basis of Tagomics' Activace™ platform.
Why women’s periods once synced with the moon — and what changed
Study reveals women's menstrual cycles follow lunar gravity, with synchronization detected during strong seasonal alignments despite artificial light effects.
Radiomics significantly outperforms clinical models for predicting NPC treatment outcome
Nasopharyngeal carcinoma (NPC) is a highly aggressive malignancy, with most patients presenting at locally advanced stages. While immune checkpoint inhibitors, such as PD-1 blockade, have reshaped treatment strategies, only a minority of patients achieve durable benefit. Accurate biomarkers for predicting treatment response remain an urgent unmet need.
Tissue-mimicking hydrogels drive cell reprogramming via matrix remodeling
The mechanical properties of tissue matrix are crucial for maintaining cell health and function. With aging, tissue matrix loses its mechanical integrity and exhibits altered biophysical properties, which are closely associated with various diseases including neurodegenerative diseases and cancers.
Study quantifies pain levels with financial compensation for clinical precision
Asking people how much money they would accept to experience pain again can provide a more accurate and comparable measure of pain levels than the familiar 1-10 scale, according to an international research team led by Lancaster University.
Researchers design factor IX variants for short- and long-term Hemophilia B management
After blood vessel damage, effective blood clotting is essential to halt bleeding. However, this process is inefficient in some individuals due to hereditary factors. Hemophilia B, for example, results from a deficiency in coagulation factor IX (FIX), which can lead to prolonged bleeding after injuries or surgery.
What’s more dangerous, road cycling or mountain biking?
Researchers in Barcelona analyzed 149 injured cyclists and found that while mountain biking accidents were more frequent, road cycling caused more severe injuries, especially head trauma. Older age strongly increased injury severity in road cyclists, highlighting a vulnerable group in need of attention.
Scientists test whether chaya leaves can lower blood sugar in diabetes
Researchers reviewed current evidence on the chaya plant (Cnidoscolus chayamansa), highlighting its nutritional profile, hypoglycemic activity in animal models, and potential as a complementary aid for diabetes management. While promising, safety, dosage, and interaction studies remain essential before clinical use.
Radiation therapy shows promise as safer alternative for severe heart rhythm disorder
Radiation therapy may offer a comparable and potentially safer alternative to repeat catheter ablation for patients with severe abnormal heart rhythms that can no longer be controlled with medication.
Second-hand smoke causes major health burden for children worldwide
Children lose 8.45 million days of healthy life each year globally due to second hand smoke, according to research presented at the European Respiratory Society Congress in Amsterdam, the Netherlands.
Five-session SBRT reduces side effects in intermediate-risk prostate cancer
For patients with intermediate-risk, localized prostate cancer, radiation therapy delivered in five sessions reduced patient-reported side effects compared to longer courses of radiation, according to results of a large, randomized phase III trial.
Post-operative radiation therapy reduces pelvic relapse in high-risk bladder cancer
Radiation therapy could be an underused tool to reduce pelvic relapse risk for patients with locally advanced, muscle-invasive bladder cancer, according to results of a new phase III randomized trial.
Menopause not linked to increased risk of disability in women with multiple sclerosis
The largest study of its kind has found menopause is not associated with an increased risk of disability in women with multiple sclerosis (MS).
Medicaid unwinding linked to drop in opioid use disorder treatment
The end of pandemic-era enrollment enhancements for Medicaid was associated with a rise in the number of people ending medication treatment for opioid use disorder, as well as a decrease in the number of people beginning such treatment, according to a new RAND study.
New TOR inhibitor rapalink-1 prolongs chronological lifespan in fission yeast
Researchers from Queen Mary University of London's School of Biological and Behavioural Sciences, using the simple fission yeast as a model, have shown that new TOR inhibitor rapalink-1 prolongs chronological lifespan.
Proton therapy and IMRT show similar outcomes in head and neck cancer trial
A new phase III clinical trial finds that intensity-modulated radiation therapy (IMRT) and proton beam therapy resulted in similar quality-of-life outcomes and low rates of side effects for people with locally advanced oropharyngeal cancer.
Genetic variant linked to liver injury after chemotherapy in colorectal cancer patients
A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe liver damage after chemotherapy.