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Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells lining the liver's tiny blood vessels.

Congenital aniridia is a rare disease caused, in most cases, by mutations in the PAX6 gene, which is essential for the development of ocular structures.

A new study suggests that pancreatic cancer may start preparing to "hide" from the immune system long before the disease becomes full-blown cancer.

Terminal ileum intubation is considered the completion step of colonoscopy and is usually performed to assess the ileum.

Research indicates that peanut butter can enhance muscle power in older adults, but its impact on overall physical function and gait speed is limited.

Findings indicate zero-alcohol advertising could serve as indirect marketing for alcohol, raising questions about its impact on adolescent drinking behaviors.

As people age, they experience a gradual decline in intrinsic capacity (IC), the combined physical and mental abilities that support independence and health. The World Health Organization recognizes IC as a central indicator of resilience in aging, yet no affordable, validated tool exists to measure it.

Breasts are necessary for breastfeeding, but their size is not decisive in terms of milk production. A large part of the breast consists of adipose tissue, and earlier theories have suggested that they function, for example, as a body fat reserve. Another theory proposes that breasts evolved through sexual selection as a signal of individual fitness, similar to facial symmetry.

High school students often have trouble getting to bed at a reasonable time, which makes it difficult for them to start school early in the morning. This is because teenagers are biologically wired to fall asleep later than adults, with their biological clock shifting progressively later throughout adolescence. The result is that most teenagers don't get enough sleep on school days, and their sleep deficits increase as the week progresses.

Physical fitness and psychological resilience develop side by side during adolescence, a life stage that lays the foundation for adult health. Cardiorespiratory endurance, muscular strength, and agility are well-known predictors of cardiometabolic health, while self-efficacy, defined as the belief in one's ability to overcome challenges, shapes motivation, persistence, and coping strategies.

ARES Scientific, a rapidly growing provider of innovative laboratory and research solutions, today announced the acquisition of Animal Care Systems (ACS), a respected leader in laboratory animal care equipment and solutions.

Radiation therapy is highly effective at killing cancer cells, but it often harms healthy skin around the treatment area, a common side effect experienced by up to 95% of cancer patients undergoing treatment. In worst-case scenarios, it can result in delayed or halted treatment.

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity compared with earlier agents, most patients either fail to respond initially or eventually develop resistance.

When Hend Alqaderiwas studying how saliva could predict the risk of diabetes or the severity of a coronavirus infection, she collected a lot of saliva samples-thousands, measuring hundreds of bacteria samples for each patient.

A Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked stress mechanisms. It highlights their biomarker and therapeutic potential in obesity and type 2 diabetes while underscoring key translational challenges, including delivery specificity and human validation.

A new study using serial liquid biopsies to track how metastatic prostate cancer evolves under treatment pressure showed that androgen receptor (AR) alterations consistently emerged and were linked to poorer outcomes across therapies.

What if healing the brain after traumatic injury starts in the gut?

A novel quantitative PET- and MRI-based imaging approach can objectively identify a recently recognized type of dementia--limbic-predominant age-related TDP-43 encephalopathy, or LATE--that is often mistaken as Alzheimer's disease.

Experts from the Translational Research in Neuroimaging and Data Science (TReNDS) Center at Georgia State University will play a key role in the largest study ever conducted to investigate the causes of profound autism in children and develop possible treatments.

In a large UK population cohort, higher weekly alcohol consumption was dose-dependently associated with greater visceral fat mass measured by DXA, independent of total body fat. Heavy drinkers showed over 10% higher proportional visceral fat compared with lower consumption groups, a pattern linked to increased cardiometabolic risk.