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Development of a polygenic risk score for pelvic organ prolapse in Chinese women
Pelvic organ prolapse (POP), a condition whose development is shaped by both genetic and clinical risk factors, significantly impairs women's quality of life, yet genetic insights into non-European populations and comprehensive risk models that integrate genetic and clinical data remain insufficiently explored.
Vegan diet with unhealthy plant foods promotes greater weight loss than Mediterranean diet
Eating a vegan diet increases consumption of plant-based foods-including those defined as "unhealthy" by the plant-based diet index-leading to greater weight loss than the Mediterranean diet, finds a new analysis by the Physicians Committee for Responsible Medicine published in Frontiers in Nutrition.
Single-cell RNA sequencing uncovers diverse CD4⁺ T-cell subtypes in pediatric lupus
Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine investigators.
Researchers uncover a new way to understand how children fare after liver transplantation
Researchers at the Icahn School of Medicine at Mount Sinai have uncovered a new way to understand how children fare after liver transplantation: by focusing not on medical test results, but on how differently parents and children perceive the child's well-being.
Identifying vulnerabilities and new targets for hard-to-treat carcinomas
Some tumors are almost impossible to treat. That's especially true for carcinomas, which don't behave like other malignancies.
New discovery could reshape how scientists think about Alzheimer’s treatment
Rutgers neuroscientist Peng Jiang was visiting his hometown of Qianshan, a city in China's Anhui province, when a neighbor came to his parents' house with a story that would stay with him.
Researchers use organoids to study the earliest moments of electrical activity in the brain
Humans have long wondered when and how we begin to form thoughts. Are we born with a pre-configured brain, or do thought patterns only begin to emerge in response to our sensory experiences of the world around us? Now, science is getting closer to answering the questions philosophers have pondered for centuries.
Research links social determinants of health to rural-urban disparities in colorectal cancer mortality rates
New research reveals that certain social determinants of health-such as socioeconomic status, household characteristics, and racial/ethnic minority status-have significant effects on rural–urban disparities in colorectal cancer mortality rates.
Kimchi consumption strengthens antigen recognition and immune regulation
Amid concerns about the simultaneous spread of multiple respiratory diseases, such as colds and influenza, with the change of seasons in current times, a recent clinical study has scientifically proven that kimchi, a traditional Korean fermented food, enhances the function of human immune cells and maintains the balance of the immune system.
Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries
Wiley expands its spectral database with over 9.5 million high-quality spectra, enhancing compound identification for researchers in various scientific fields.
Study: Fewer than 1 in 4 preschoolers meet the recommended daily physical activity levels
Fewer than 1 in 4 children aged 2 to 4 meet the recommended daily physical activity levels, a new study has found.
Most Medicaid patients do not receive life-saving drugs for opioid use disorder
A US study of more than a million Medicaid enrollees, newly diagnosed with opioid use disorder (OUD), finds most – nearly seven in 10 – are not receiving access to potentially life-saving drugs within six months.
COVID vaccine tech could help prevent muscle damage from snakebites
The same technology used in COVID-19 vaccines could help prevent muscle damage from snakebites, according to a new study published in Trends in Biotechnology today [24 November].
Elevated levels of five blood proteins can help predict mortality risk
Elevated levels of five proteins in our blood can help predict risk of mortality, a new study from the University of Surrey finds.
Novel nanowire platform mimics brain tissue to study astrocytes
Scientists have engineered a nanowire platform that mimics brain tissue to study astrocytes, the star-shaped cells critical for brain health, for the first time in their natural state.
Dexamethasone shows potential to fight therapy-resistant breast cancer metastases
The drug dexamethasone supplements cancer treatments to alleviate side effects of chemotherapy such as nausea or inflammation.
New Cochrane reviews confirm the effectiveness of HPV vaccines in preventing cervical cancer
Two new Cochrane reviews show strong and consistent evidence that HPV vaccines are effective in preventing cervical cancer and pre-cancerous changes, especially when given to young people before they are exposed to the virus.
Hearing loss emerges as a key early warning sign for Alzheimer disease
Hearing loss also predicts a significantly higher risk of dementia, especially in APOE ε4 carriers, highlighting its value as an early risk marker.
Study finds GLP-1 drugs improve strength and reverse aging biology in mice
Researchers showed that GLP-1 receptor agonism counteracts aging across multiple organs in mice, improving strength and reversing molecular aging signatures without meaningful effects on body weight.
These benefits depended largely on hypothalamic GLP-1R signaling and closely mirrored the anti-aging patterns produced by rapamycin.
Does coffee truly boost memory and focus or is it all hype?
Coffee’s bioactive compounds, especially caffeine, show potential cognitive, neuroprotective, and neuroplasticity benefits across animal and human studies. However, most findings are observational, mechanisms remain uncertain, and optimal intake is still unclear.




