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Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumors and identified distinct neighborhoods of proliferating and dormant cells.

A new approach to defining obesity could help physicians better determine which patients need more intensive treatment by focusing on the effects of excess adiposity on organs and tissues rather than relying primarily on whether a person meets a set of metabolic risk thresholds.

An estimated 10 million Americans have atrial fibrillation (AFib), according to the National Institutes of Health's National Heart, Lung, and Blood Institute.

A $1.5M grant has been awarded to William Van Nostrand, co-executive director of the University of Rhode Island's George & Anne Ryan Institute for Neuroscience and professor of pharmaceutical and biomedical sciences in the URI College of Pharmacy, to study cerebral amyloid angiopathy (CAA), a disease prevalent in the elderly population and commonly found in patients with Alzheimer's disease.

Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature aging.

The study, which tracked more than 500 Spanish girls between the ages of 7 and 10, links the presence of certain fungicides in urine to early menarche and that of the insecticide chlorpyrifos to delayed menarche, highlighting the impact of pesticides on pubertal development.

High salt (HS) intake is a major global health concern, closely linked to hypertension and growing evidence of cognitive and emotional decline.

While existing digital health tools can provide valuable information to offset poor nutrition, older adults with pre-frailty and frailty want to engage with these tools easily, to support their autonomy, dietary self-management and healthy aging.

A "leaky gut" might increase the severity of food allergies, according to new research conducted in mice and published in The Journal of Immunology.

Community gathering places, where residents lead group activities, have been promoted across Japan as part of long-term care prevention efforts to extend healthy life expectancy.

Diabetic foot ulcers are among the most serious complications of diabetes because prolonged inflammation, poor circulation, and defective angiogenesis can leave wounds open for months and increase the risk of infection and amputation.

Linguistic models that analyzed the words children used when talking about stressful events proved better at predicting future mental health problems than a panel of human experts.

Researchers analyzed 485 mother-child pairs in Canada to examine whether estimated fluoride intake from tea during pregnancy was associated with IQ at ages 3 to 4. Each 0.5 mg/day increase was associated with a 2.24-point lower full-scale IQ score, although the observational design and estimated exposure prevent causal conclusions.

Researchers modeled how replacing conventional global shipping fuels with hydrogen could change PM2.5 and ozone pollution, premature mortality, and monetized health benefits. Under complete transition, the model estimated 129,458 fewer premature deaths and US$284 billion in annual monetized health benefits, although some regions experienced increased pollution from hydrogen production or altered ozone chemistry.

In a new study, researchers from The University of Texas MD Anderson Cancer Center have uncovered insights that may help explain how rapid-acting antidepressants, such as ketamine and psychedelics, can reduce symptoms in difficult-to-treat depression.

People who live by the coast in midlife are more likely to have worse health, finds a new study in England and Wales led by UCL researchers.

Researchers analyzing claims from more than 10.1 million commercial insurance and Medicare Advantage enrollees found that semaglutide use was associated with a 49% lower adjusted hazard of COVID-19-related death. The observational findings corroborate earlier SELECT trial results but do not establish causation, making further prospective research essential.

Researchers linked 129,136 global human and swine Salmonella genomes with sampling from a Guangdong pork supply chain to examine how downstream stages relate to antimicrobial resistance. The study suggests slaughterhouse and retail interfaces may concentrate S. 4,[5],12:i:- ST34, resistant strains, and mobile resistance elements, supporting broader One Health surveillance beyond farms.

A ten-year study of residents of the city of São Paulo, Brazil, revealed that leisure-time physical activity is highly unequal and that the gap between social strata is widening.

Researchers at the UC Davis School of Medicine have identified a naturally occurring metabolite that repairs gut damage caused by HIV infection and significantly improves the effectiveness of antiretroviral therapy (ART) in the nonhuman primate model of HIV/AIDS.