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Cold temperatures may raise eye pressure in glaucoma patients
Lower air temperatures may be associated with an increase in the fluid pressure inside the eye-a cardinal cause of glaucoma-and should be taken into consideration when treating patients with the condition, suggest the findings of research published online in the British Journal of Ophthalmology.
$5.7 million NIH grant supports research on why lean people develop insulin resistance
A Wayne State University research team was awarded a $5.7 million grant from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health focused on discovering the biological mechanisms that may help explain why some lean people develop insulin resistance while some people with obesity remain sensitive to insulin.
Maternal depression linked to neurodevelopmental disorders in children
Children of mothers with depression had higher rates of certain neurodevelopmental disorders regardless of whether they were exposed to antidepressants in the womb, reports a new study led by Saraid McIlvride of the University of Glasgow, UK, published September 29th in the open access journal PLOS Medicine.
Antibiotic resistance gene helps C. difficile spores withstand hospital disinfectants
Antibiotic resistance is supercharging dangerous gut bacteria to withstand even hospital-grade disinfectants intended to kill them.
Study identifies three cell clusters driving pancreatic cancer-induced cachexia
Research published today in Cell identifies three small subclusters of cells driving pancreatic cancer-induced cachexia, a muscle-wasting and fat-loss condition that makes patients less tolerant of cancer treatment.
NIH awards $7.6 million grant to advance polyaminopathy research
A first-of-its-kind NIH grant was awarded to Michigan State University College of Human Medicine and Corewell Health. Co-investigators André Bachmann, PhD, MS, professor and associate chair for research in the MSU Department of Pediatrics and Human Development, and Caleb Bupp, MD, FACMG, division chief of Medical Genetics and Genomics at Corewell Health Helen DeVos Children's Hospital, will advance understanding of how polyaminopathies work.
Neck lymph node removal surgery may disrupt brain waste clearance
Surgery to remove lymph nodes in the neck may interfere with cerebrospinal fluid (CSF) drainage from the brain, contributing to cognitive impairment, according to new multicenter research led by Weill Cornell Medicine scientists.
Menthol prolongs nicotine effects in rats exposed to e-cigarettes
Menthol, a common flavoring for both traditional cigarettes and e-cigarettes, may do more than simply change how nicotine tastes or feels.
Social connection has a price, and it varies from person to person
Researchers found that people were willing to spend slightly more on social than on non-social experiences, suggesting that companionship has measurable economic value. Greater perceived social support was associated with more social choices and spending, while higher autistic-trait scores and broader social dysfunction were associated with lower valuation of social experiences.
People make first choices faster as outcomes grow less predictable, study finds
In three online experiments involving 300 US adults, researchers varied how reliably rewards matched their labels, how often rewards changed, and whether chosen movements went as intended. Participants responded faster before their first choice as randomness increased, while computational models suggested they used simpler, less precise decision policies.
Bile DNA sequencing helps identify hidden pancreatobiliary tumors
Distinguishing malignant from benign biliary strictures remains a major clinical challenge. Endoscopic retrograde cholangiopancreatography (ERCP)-guided cytology and biopsy may be inconclusive, particularly in early-stage disease or when tissue is scarce.
University of Liverpool study tracks long-term impact of non-nutritive sweetened soft drinks
Researchers at the University of Liverpool have conducted the longest and most comprehensive randomized controlled trial on non-nutritive sweetened (NNS) soft drinks.
Perceiving life as getting worse raises suicidal ideation risk
New research finds that people are far more likely to report suicidal ideation when they perceive their life to be getting worse relative to their own recent past, rather than because of their income, age or health status alone.
Targeting specific nuclear receptor could help preserve aging muscle function
Scientists in the Gerhart-Hines Group pinpoint a molecular cause of muscle aging, and a possible fix. By investigating how muscles adapt to age and disease-related decline, the scientists discovered the involvement of a druggable nuclear receptor, ERRγ, that could be targeted to preserve muscle function.
Microplastics impair liver function and increase fat in mice
Microplastics appear capable of significantly impairing the function of phagocytes in the liver, at least in mice. In turn, this disrupts the metabolism of this vital organ and increases the build-up of fat inside it.
War shocks Ukrainian mental health with widespread trauma and PTSD
A national survey of Ukrainian residents provides one of the clearest estimates to date of the psychological impact of the ongoing war.
Veterinary sedative in fentanyl supply spikes severe withdrawal cases
A powerful veterinary sedative, medetomidine, is increasingly infiltrating the street supplies of the already deadly opioid fentanyl, with patients suffering from its withdrawal quadrupling in recent years, according to a new analysis by researchers at the Perelman School of Medicine at the University of Pennsylvania.
BD² announces third funding call for clinical sites to improve bipolar disorder care
Breakthrough Discoveries for thriving with Bipolar Disorder (BD²) today announced its third call for applications for clinical sites to join the BD² Integrated Network.
New study uncovers breakthrough window to prevent brain metastasis
Metastasis, the process by which a tumor spreads throughout the body, is associated with the majority of cancer deaths.
Radioactive collagen tiles double survival for brain metastasis patients
A multicenter clinical trial led by researchers at The University of Texas MD Anderson Cancer Center has found that implanting collagen tiles during brain surgery to deliver targeted radiation therapy dramatically improved tumor control, lowered the risk of recurrence and improved overall survival compared to current standard of care for patients with newly diagnosed brain metastases in need of surgical resection.




