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What happens in the brain on psychedelics? Scientists identify a common circuit pattern
Researchers combined 11 international resting-state fMRI datasets to map how psychedelic drugs reshape brain connectivity across cortical and subcortical circuits. The mega-analysis found a shared signature of stronger coupling between transmodal association networks and unimodal or sensorimotor systems, alongside selective and variable reductions in within-network connectivity.
New blood test spots four cancers and other diseases by stripping away healthy DNA noise
MethylScan is a new low-cost cell-free DNA methylome test that removes much of the healthy blood DNA background, helping rare disease signals stand out more clearly. In more than 1,000 people, it showed strong performance for detecting four cancers, classifying liver diseases, and identifying organ-specific damage.
Geographic disparities persist in the decline of U.S. cancer deaths
In 1991, the U.S. experienced a significant shift in cancer death rates, as, for the first time, deaths began a steady decline that continues to the present day. Researchers at Mississippi State's Social Science Research Center, in partnership with scientists at Oak Ridge National Laboratory, examined this decline to identify where and who benefited the most from this dramatic improvement.
Treating heart failure patients with i.v. furosemide and HSS reduces inflammatory, remodeling markers
A new research paper was published in Volume 18 of Aging-US on March 26, 2026, titled "Effects of intravenous furosemide plus small-volume hypertonic saline solutions on inflammatory, remodeling markers and epigenetics signatures of patients with congestive acute decompensated heart failure (ADHF)."
TIFR researchers identify protein essential for survival and function of vomeronasal sensory neurons
Researchers at the Tata Institute of Fundamental Research (TIFR), Hyderabad, have identified a mammalian protein, Cnpy1 (Canopy1), that is essential for the survival and function of vomeronasal sensory neurons in mice.
Navigated TMS significantly boosts combat PTSD recovery rates
An advanced version of a procedure using magnetic fields to stimulate brain nerve cells in treating depression was significantly effective for 85% of active military and veterans suffering from combat post-traumatic stress disorder enrolled in a recent study, when added to psychotherapy.
Study reveals racial and ethnic disparities in pediatric e-scooter injuries
As electric scooters (e-scooters) become more available in cities and urban areas, injuries are becoming more common - especially among teenage boys.
Lactate modification fuels drug resistance and immune escape in cancer
Published in Current Molecular Pharmacology, a comprehensive review led by Yong Xu and colleagues from Shanghai Pulmonary Hospital explores the emerging role of lactylation, a post-translational modification driven by lactate, in lung cancer progression and drug resistance.
Review identifies TREM-1 as key amplifier of inflammatory diseases
Published in Current Molecular Pharmacology, a comprehensive review by Eman R. Al Sawy and colleagues from Cairo University consolidates evidence on the triggering receptor expressed on myeloid cells-1 (TREM-1) as a central amplifier of inflammatory responses.
High-resolution model identifies nationwide plague risk zones in Madagascar
Announcing a new article publication for Zoonoses journal. Plague (Yersinia pestis) remains endemic in Madagascar and causes recurrent outbreaks leading to substantial mortality.
WSU researchers use spice extracts to enhance medical bone implants
An extract of turmeric and ginger helps bone implants bond strongly while killing bacteria and cancer cells, according to new research from Washington State University with implications for millions of patients with joint replacements and bone cancer.
Analysis reveals long-term male bias in European meat access
Access to nutritious food is a fundamental pillar of human success, but such access has been unequal throughout history. In pre-industrial European societies, meat was a highly sought-after food, and access to it was often related to a higher social status.
Study investigates how the brain maintains consciousness during physiological failure
Near-death experiences continue to challenge the scientific understanding of consciousness: how can vivid and structured reports be explained at moments of extreme physiological failure?
Integrated motor exercise improves core ADHD symptoms and executive function
Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in childhood and is marked not only by inattention, hyperactivity, and impulsivity, but also by weaknesses in executive functions such as inhibition, working memory, and cognitive flexibility.
Study reveals how Bcl-2 protein blocks cancer cell death
Researchers at Umeå University have contributed new insights into how cancer cells protect themselves from cell death.
Longer working hours associated with higher risk of nonrestorative sleep and poor mental health
Mental load, invisible work, "the extra shift"; no matter the newly coined term, unpaid work in the domestic sphere, predominantly done by women, is a hidden burden eating away at the sleep and mental health of those tasked with it.
New obesity definition could delay treatment and widen health gaps
The Lancet obesity framework aims to improve risk assessment but risks delaying treatment and deepening health inequities, according to recent evaluations.
Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into adrenal tissue or sympathetic ganglia take a wrong turn, and a child is born harboring a malignancy that may not declare itself for months.
Declining booster uptake after vaccine schedule change in England
The change to a 1+1 pneumococcal vaccine schedule in England highlights rising inequalities in booster uptake, threatening protection for at-risk children.
Could vitamin D in midlife protect your brain from early Alzheimer’s?
Higher serum vitamin D in midlife is associated with reduced tau burden in the brain, highlighting its potential role in early dementia risk assessment.




