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Persistent gut microbiome changes linked to sustained colorectal cancer risk
More than a decade after removal of an adenoma-a precancerous mass-from the colon, alterations to the gut microbiome and metabolites remain and may drive heightened risk of colorectal cancer (CRC), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.
Extreme trait values often have simpler genetic explanations than thought
Researchers at the Icahn School of Medicine at Mount Sinai have found evidence that people who fall at the extreme high or low ends of certain traits, such as cholesterol, blood glucose, height, and age at menopause, are more likely to have a simple genetic explanation than previously thought.
Degrading mutant KRAS protein induces greater lung cancer regression
KRAS is one of the oncogenes most frequently altered in cancer, mutated in approximately one-third of lung adenocarcinomas.
Prenatal therapy for cystic fibrosis improves lifelong health outcomes
This Cystic Fibrosis Awareness Month, Children's Hospital Colorado (Children's Colorado) is highlighting a growing shift in care: starting cystic fibrosis treatment before birth to improve lifelong health outcomes and reduce hospital stays.
Study reveals how immune cells alter vascular plaque formation
A new LMU study shows how differently immune cells influence the formation of dangerous vascular deposits - and identifies miR-147 as a potential starting point for future therapies.
Virtual reality navigation deficits predict future brain volume loss
Alzheimer's disease (AD) often begins long before it is clinically recognized, with subtle brain changes emerging years before noticeable memory loss or cognitive decline.
Naturally occurring peptide can reverse drug resistance in melanoma
Melanoma is one of the deadliest forms of skin cancer, due in large part to its ability to rapidly develop resistance to treatment.
Graphic cigarette ads may accidentally push smokers toward vaping
Graphic anti-smoking ads can lead smokers to reconsider their habit, but in the absence of similar warnings for e-cigarettes, they make some smokers more inclined to vape than quit.
EEG reveals how coffee may secretly lower sleep quality
Evening coffee has sparked controversy for years. Some people fall asleep without difficulty, while others toss and turn for half the night.
Poor lipid metabolism may reduce cognitive performance in teens
A new Finnish study shows that blood markers of dysfunctional lipid metabolism are associated with poorer cognitive function in 15-17-year-olds.
Prenatal forever chemical exposure may affect puberty timing in children
An EHU-University of the Basque Country and Biogipuzkoa Health Research Institute study has linked certain chemicals measured during the first trimester of pregnancy to the subsequent onset of puberty in the children.
Blocking sugar modification could boost breast cancer immunotherapy success
Immunotherapies such as so-called checkpoint inhibitors activate the body's own immune system to fight cancer cells and have revolutionized the treatment of many types of tumor.
