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How a single gene reshapes pain perception through polyamine signaling
Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.
Most Americans drink less juice than guidelines allow, study finds
A new study of NHANES 2017–2023 data shows that most Americans drink far less 100% fruit juice than the Dietary Guidelines allow. Juice consumption was linked to better diet quality, higher nutrient intake, and did not displace whole fruit.
Study shows brain keeps internal body map intact after amputation
Researchers tracked brain activity before and after arm amputation and found that hand and lip maps in the cortex remained remarkably stable for up to five years. This challenges decades-old assumptions of large-scale remapping and supports the idea of a resilient internal body model.
A 9-point checklist to improve AI-based image analysis in pathology
A new article in Veterinary Pathology introduces a 9-point checklist designed to improve the reporting quality of studies that use artificial intelligence (AI)-based automated image analysis (AIA). As AI tools become more widely used in pathology-based research, concerns have emerged about the reproducibility and transparency of published findings.
iconPCR™: Powering the next wave of metagenomics and microbiome discovery
The landscape of metagenomics and microbiome research is evolving at breakneck speed. As sequencing technologies improve and the demand for high-resolution, bias-free microbial data grows, the bottleneck is shifting from sequencing itself to the quality of upstream sample preparation.
Next-gen sequencing reveals the regulatory potential of the non-coding genome
The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark achievements of the Human Genome Project (HGP), scientists have increasingly focused on deciphering the non-coding regions of the human genome, which comprise approximately 98% of the genetic material.
n6™ announces strategic partnership with SeqCenter to deliver unmatched data quality in metagenomics
n6 is proud to announce a strategic partnership with SeqCenter, who is launching a groundbreaking full-length 16S sequencing service at FEMS Micro.
WHO and WMO report highlights extreme heat's impact on workers
The World Health Organization (WHO) and the World Meteorological Organization (WMO) have published a new joint report and guidance highlighting the growing global health challenges posed by extreme heat on workers.




