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HPV infections in women aged 27+ highlight the need for updated vaccination policies, emphasizing ongoing risk and the importance of preventive healthcare.

The use of mailed FIT-DNA kits in community health centers significantly increases colorectal cancer screening, though follow-up colonoscopy rates remain low.

Sapio Sciences, the AI lab informatics company, today announced that Claude Cowork, Anthropic's agentic AI assistant, is now integrated with the Sapio Platform via Sapio Elain, the AI co-scientist.

A review of 1,801 registered CAR T clinical trials shows that multifunctional designs now account for 533 trials and 33% of new CAR T products submitted for clinical testing in 2025. The field is shifting toward multitargeted, safety-controlled, cytokine-secreting, and checkpoint-modulating CAR T cells, but manufacturing, regulation, and limited clinical outcome data remain key barriers.

Single-cell RNA sequencing is giving researchers a clearer view of why some CAR-T cells persist, expand, kill tumors effectively, or become exhausted. The review synthesizes 44 clinical scRNA-seq studies involving 500 patients and highlights how exhaustion, memory, cytotoxicity, clonal diversity, and metabolism may shape CAR-T responses.

A new non-invasive brain stimulation technique known as accelerated continuous theta burst stimulation (a-cTBS) improves social communication at one month follow up and has a favorable safety profile in children with autism, finds a trial from China published by The BMJ today.

The Nuffield Department of Women's & Reproductive Health at the University of Oxford, together with Serac Healthcare Limited announces the publication of Phase 2 data in The Lancet Obstetrics and Gynaecology.

A large South Korean study published by The BMJ today finds no increased risk of psychiatric or neurodevelopmental disorders, such as ADHD and autism, in children whose mothers used sedative drugs (benzodiazepines or Z-hypnotics) during pregnancy.

The responses to a national survey published today have revealed tunnel construction workers across Australia say they face significant exposure to silica dust, a hazardous dust that can cause incurable diseases like silicosis and lung cancer.

A nationwide Korean cohort study of 258,367 mother-child pairs found that maternal pre-pregnancy BMI was associated with developmental delay risk in children aged 18 to 36 months. Children of underweight mothers showed modest early risks that later attenuated, while obesity-related risks persisted across developmental domains.

Brief brisk walking breaks during prolonged sitting improved post-meal interstitial glucose responses in healthy adults after carbohydrate-rich meals, with the strongest effects seen in women. Gluteal fat showed a more stable glucose pattern than abdominal fat, suggesting it may help buffer carbohydrate-related glucose rises through depot-specific uptake and lipid-synthesis pathways.

The AHA scientific statement calls for a life-course approach to brain health that integrates cognitive, emotional, behavioral, vascular, environmental, inflammatory, sleep, microbiome, and social factors. It highlights how early-life exposures, mental health, pollution, chronic inflammation, poor sleep, gut dysbiosis, and socioeconomic adversity may shape brain resilience and later-life cognitive decline.

A new national survey reveals many women are unsure about when to start mammogram screening for breast cancer and believe they should start later than doctors recommend.

Brain tumors cannot always be successfully treated with conventional therapies. A team from Empa and the hospital network HOCH Health Ostschweiz is therefore developing nanozymes that can attack cancer cells directly in the brain during tumor surgery.

Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.

Chinese researchers report that academic burnout can push adolescents towards excessive online gaming. Using a large-scale cross-sectional survey, the researchers assessed the associations among academic burnout, internet gaming, depressive symptoms, and attentional bias.

A new research paper was published in Volume 17 of Oncotarget on April 28, 2026, titled "Targeted therapeutics and U.S. population-level mortality trends in multiple myeloma: A SEER-based analysis from 1975 to 2023."

A new study by researchers at The University of Texas at El Paso has identified a significant rise in Valley fever cases in El Paso over the past decade and found strong connections between the disease and extreme weather, wind and airborne dust.

Researchers at Mass General Brigham Heart and Vascular Institute and collaborators have developed and validated a new genetic risk test that can estimate a person's inherited risk for eight common cardiovascular conditions, offering a more comprehensive approach to prevention.

A team led by metabolism researcher Prof Timo D. Müller at Helmholtz Munich has developed a new approach for treating obesity and type 2 diabetes: a hybrid molecule uses the well-known GLP-1/GIP signalling pathway as a "door opener" and delivers an additional metabolic modulator specifically into the target cells.