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Bioengineered E. coli bacteria can now produce rhododendron-derived drugs
Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities.
Frozen in time: Ancient bacteria reveal evolution of drug resistance
Bacteria have evolved to adapt to all of Earth's most extreme conditions, from scorching heat to temperatures well below zero.
Nuclear speckles may be the unseen architects of viral infection spread
Recent research reveals that nuclear speckles play a key role in modifying viral messenger RNAs and in their transport out of the nucleus; therefore, nuclear speckles are an important subject of study in understanding viral infections.
Study links microbe-rich diets with better insulin and cholesterol markers
This exploratory Australian study developed a database to estimate live microbe content in foods and examined associations with cardiometabolic health indicators in adults. Higher intake of foods estimated to contain live microbes was linked with favourable markers such as higher HDL cholesterol and lower BMI, insulin, and waist circumference, although causality cannot be inferred.
Psychedelic effects of ketamine do not predict sobriety
The psychedelic effects recreational users often seek from taking ketamine do not predict the therapeutic benefits for people being treated for alcohol use disorder.
Do cocoa flavanols influence heart and fatty liver risk factors?
A recent Nutrients review examined whether cocoa-rich dark chocolate influences cardiovascular and metabolic dysfunction-associated steatotic liver disease risk factors through antioxidant, anti-inflammatory, and endothelial effects. Evidence suggests modest improvements in biomarkers, but most data come from short-term studies, so definitive clinical benefits remain unproven.
Sleep loss triggers brain fluid pulses that impair attention, study finds
Sleep deprivation causes attentional lapses that coincide with coordinated changes in brain activity, pupil diameter, blood flow, and cerebrospinal fluid dynamics. These findings suggest attention failures reflect a transient brain–body state linked to sleep pressure rather than isolated neural errors.
Healthy diets link to longer life regardless of longevity genes, large study finds
Adherence to five established healthy dietary patterns was associated with lower mortality and modestly longer life expectancy in a large UK cohort. These associations were largely independent of genetic predisposition to longevity, suggesting diet quality may influence lifespan regardless of inherited risk.
Specific neurobiological link identified between hearing loss and cognitive decline
Presbycusis is a prevalent form of age-related hearing loss that also hinders speech recognition. While scientists have linked hearing loss to an increased risk of cognitive decline, the biological "bridge" between the two has remained unclear.
Study reveals a new facet of how pancreatic cancer cells regulate autophagy
A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.
Study reveals persistent gaps in child mental health access
A new study led by the Harvard Pilgrim Health Care Institute finds that mental health care gaps for U.S. children remain stark: one in five households reported a child needing treatment, yet nearly a quarter didn't receive it, and many who did still struggled to access care.
Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.
Dysplasia grade predicts colorectal cancer risk in people with IBD
People with inflammatory bowel disease (IBD) and precancerous colorectal lesions are much more likely to develop colorectal cancer, a new study shows.
Infant bifidobacteria may protect against childhood allergies
Certain gut bacteria in infants may reduce the risk of developing allergies later in childhood. This is the finding of new research from the ALADDIN study at Karolinska Institutet, published in Nature Microbiology.
Senescent astrocytes identified as key drivers of Alzheimer's progression
Researchers from the NeuroAD group (Neuropathology of Alzheimer's Disease) within the Department of Cell Biology, Genetics and Physiology at the University of Málaga, also affiliated with IBIMA-BIONAND Platform and CIBERNED, have made a pioneering breakthrough in the fight against this disease by identifying astrocytes as a promising cellular target for the development of future therapies.
Unlocking the potential of phytochemicals in rheumatoid arthritis treatment
Announcing a new article publication for BIO Integration journal. In recent years, phytochemicals and medicinal plants have increasingly been used to treat autoimmune diseases, such as rheumatoid arthritis (RA).
Study explores perspectives of healthcare practitioners on environmental sustainability in healthcare
Healthcare systems worldwide are increasingly recognizing the importance of environmental sustainability, yet little is known about how healthcare professionals perceive and implement sustainable practices in Kazakhstan.
Probiotic form matters for memory, mood, and more
How you take probiotics can affect their impact on the brain. A study from örebro University points to new possibilities for personalized approaches, depending on whether the primary aim is, for example, to improve memory or reduce depression.
Study quantifies the economic implications of living with HIV
A recent study, published in Nature Communications, shows that in the Netherlands, people who are diagnosed with HIV are less likely to be employed, work fewer hours, earn less income, and are more likely to receive disability benefits up to seven years after diagnosis.
Optimization of CAR T cells to destroy solid tumors
A team led by LMU physician Sebastian Kobold has found a way to allow the body's immune system to destroy solid tumors.




