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Study reveals genetic signatures linked to HIV-related cognitive impairment

Rss Feed - Wed, 01/14/2026 - 21:34
Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.

Rare immune events link Epstein Barr virus to early multiple sclerosis damage

Rss Feed - Wed, 01/14/2026 - 21:29
Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.

Bradycardia emerges as key clinical sign of xylazine-opioid overdose

Rss Feed - Wed, 01/14/2026 - 21:26
Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.

Age-tailored therapies needed for treating the young and old with sepsis

Rss Feed - Wed, 01/14/2026 - 14:01
Dealing with an infection isn't as straightforward as simply killing the pathogen. The body also needs to carefully steer and monitor its immune response to prevent collateral damage.

Heart failure care gaps found among Asian American ethnic groups

Rss Feed - Wed, 01/14/2026 - 13:19
Using nearly a decade of data (2015–2023) from 800+ U.S. hospitals and more than 700,000 patients overall, Northwestern researchers found that when Asian American heart failure patients are separated by ethnicity, rather than grouped together as "Asian," important differences in care emerge across groups including Filipino, Vietnamese, Chinese, Asian Indian, Korean and Japanese patients.

HIF1 protein identified as key driver of tendon pain

Rss Feed - Wed, 01/14/2026 - 13:10
Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems.

Post-meal blood sugar spikes linked to increased Alzheimer's risk

Rss Feed - Wed, 01/14/2026 - 12:47
A new study led by researchers from the University of Liverpool has found that spikes in blood sugar after meals may increase the risk of Alzheimer's disease.

Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis

Rss Feed - Wed, 01/14/2026 - 12:25
Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.

WSU study reveals gaps in end-of-life care education for doctors

Rss Feed - Wed, 01/14/2026 - 12:09
Doctors encounter death and dying significantly more than most people. It's the price of saving lives and helping people.

RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model

Rss Feed - Wed, 01/14/2026 - 12:03
Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.

Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study

Rss Feed - Wed, 01/14/2026 - 11:58
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden.

PFAS exposure linked to gestational diabetes and insulin problems

Rss Feed - Wed, 01/14/2026 - 11:51
Exposure to per- and polyfluoroalkyl substances (PFAS), a class of highly persistent environmental chemicals commonly referred to as "forever chemicals," is associated with a higher risk of gestational diabetes mellitus and altered markers of insulin resistance and insulin secretion, according to a new systematic review and meta-analysis led by researchers at the Icahn School of Medicine at Mount Sinai.

DLL3 on circulating tumor cells predicts tarlatamab success in lung cancer

Rss Feed - Wed, 01/14/2026 - 11:27
A team led by investigators at the Mass General Brigham Cancer Institute has discovered that a particular marker on tumor cells circulating in the blood indicates whether a patient with lung cancer will experience a lasting response to a newly approved immunotherapy called tarlatamab.

Endocrine-disrupting chemicals and adverse life events during pregnancy affect children's development

Rss Feed - Wed, 01/14/2026 - 11:07
Research at Karlstad University shows that exposure to endocrine-disrupting chemicals and adverse life events during pregnancy can influence children's behavior and brain development.

Long-term singles experience sharper decline in life satisfaction and well-being

Rss Feed - Wed, 01/14/2026 - 10:07
More and more young adults abstain from entering committed romantic relationships, and this may be affecting their well-being.

Cannabidiol could become a therapeutic tool for fetal alcohol spectrum disorder

Rss Feed - Wed, 01/14/2026 - 09:55
Cannabidiol (CBD) could become a therapeutic tool to address some of the most frequent and disabling consequences of fetal alcohol spectrum disorder (FASD), a condition caused by alcohol exposure during pregnancy.

DTU researchers discover gut bacteria link to reduced allergy and asthma risk

Rss Feed - Wed, 01/14/2026 - 08:33
Researchers from DTU have patented an invention that uses naturally produced substances from gut bacteria of the bifidobacteria type to reduce the risk of allergies and asthma.

New metabolomic signature predicts type 2 diabetes risk beyond traditional factors

Rss Feed - Wed, 01/14/2026 - 08:29
Diabetes, a metabolic disease, is on the rise worldwide, and over 90 percent of cases are type 2 diabetes, where the body does not effectively respond to insulin.

Research shows racial-ethnic differences in the risk of pregnancy-related high blood pressure

Rss Feed - Wed, 01/14/2026 - 08:25
The risk of pregnancy-related high blood pressure varied markedly among subgroups of Asian American, Native Hawaiian and Pacific Islander people, highlighting the need for tailored prevention and treatment, according to research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

Specific foods linked to autism risk via immune pathways

Rss Feed - Wed, 01/14/2026 - 06:01
Genetic and clinical data suggest dietary factors may influence autism risk via immune pathways, highlighting the need for further research in this area.

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