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Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors' ability to evade attack by the body's immune system, a new study shows.
Smokefree generation law could slash youth smoking decades earlier
New research, led by experts at the University of Nottingham, has found that smoking prevalence among 12 to 30-year-olds in England could drop below 5% decades earlier than expected, if the government progressively raises the age of tobacco sale.
Review links betel nut addiction to cancer, heart disease, and metabolic risks
This review examines the epidemiology, health risks, neurobiological mechanisms, and emerging treatments related to betel nut addiction worldwide. It highlights strong links with oral cancer, cardiometabolic disease, and addiction pathways while noting limited established therapies and the need for coordinated public health strategies.
Safety perceptions of major vaccines show significant drop over the past three years
In a winter marked by flu outbreaks, the persistence of Covid-19, and surges of measles cases across the United States, an Annenberg survey finds that a sizable majority of Americans think the three vaccines that combat these potentially deadly illnesses are safe to take, although perceptions of the safety of all three vaccines showed a statistically significant drop over the past three years.
Addiction consults improve care for drug-related eye infections
Eric Gaier, MD, PhD, and Dean Eliott, MD, of the Department of Ophthalmology at Mass Eye and Ear, a member of the Mass General Brigham healthcare system, are co-authors of a paper published in Ophthalmology Retina, "Substance Use Disorder Interventions and Ophthalmic Outcomes for Injection Drug Use-Associated Endogenous Endophthalmitis."
Group intervention reduces burnout among foster carers
A group-based support program for foster carers significantly improves carer wellbeing, reduces burnout and stress, and strengthens relationships with children in care, while also offering good value for money, finds a new study led by a UCL researcher.
Global report highlights inequities in pediatric palliative care
Nearly all the world's 10.6 million children experiencing serious health-related suffering (SHS) live in low- and middle-income countries with little to no access to palliative care specialized care for their illness, according to a comprehensive new report published in The Lancet Child & Adolescent Health.
Analysis finds aerobic exercise to be most effective for reducing depression and anxiety
Aerobic exercise, such as running, swimming, and dancing, may be most effective for relieving the symptoms of depression and anxiety, finds an overarching (umbrella) review and data synthesis of the available evidence, published online in the British Journal of Sports Medicine.
Non-native birds drive widespread avian malaria transmission in Hawaii
New research on avian malaria, which has decimated Hawaii's beloved birds, explains how non-native birds play a key role in transmission and contribute to the widespread distribution of the disease.
High-fat diets cause more damage to metabolic health than carbohydrates
In recent years, many media reports and social media influencers have emphasized the dangers of eating too many carbohydrates.
High adherence and safety found in short TB treatments
A study comparing one- and three-month antibiotic treatments to prevent active tuberculosis (TB) finds that a high percentage of patients successfully completed both regimens and suffered few adverse side effects.
Polygenic analysis provides new insight into hypermobile Ehlers–Danlos syndrome
Hypermobile Ehlers–Danlos syndrome (hEDS) is one of the most common heritable connective tissue disorders.
Niacin shows promise in improving treatment for glioblastoma patients
Edward (Ed) Waldner had no idea why he didn't feel well but he knew he didn't feel like himself. At 55-years of age he felt exhausted all the time.
Defective ASTN1 gene linked to developmental delay and neurological disorders
Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice, and its role in brain development.
Eating fewer foods of concern may protect the heart beyond pills
A prospective cohort study in adults with hypertension and or hypercholesterolemia found that lower intake of ultra processed foods or foods flagged by front of pack nutrition warnings was associated with reduced cardiovascular disease risk. These associations persisted regardless of cardioprotective medication use, suggesting dietary quality contributes independently to cardiovascular prevention.
New nanoparticles enable the removal of melanoma tumors with low-power laser
Researchers at Oregon State University have developed and tested in a mouse model a new type of nanoparticle that enables the removal of melanoma tumors with a low-power laser.
Stress hormones rewire immune system during periods of food scarcity
When food is scarce, stress hormones direct the immune system to operate in "low power" mode to preserve immune function while conserving energy, according to researchers at Weill Cornell Medicine.
Fall prevention programs in emergency departments improve safety for seniors after discharge
Falls are one of the most common reasons older adults are treated in the emergency department, and many patients are discharged home the same day.
Researchers uncover mechanisms of three mismatch repair deficient high-grade glioma subtypes
Researchers have uncovered the mechanisms behind three unique subtypes of mismatch repair deficient high-grade gliomas.
Work productivity declines for adults living with tinnitus symptoms
A new study has revealed the significant effect tinnitus can have on people's working lives, with nearly one in five adults reporting they have had to cut their working hours or leave employment altogether because of the condition.




