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Researchers at University of California San Diego School of Medicine, the Salk Institute and Sanford Burnham Prebys have received a four-year, $13 million award from the California Institute for Regenerative Medicine (CIRM) to investigate how to reverse age-related neurodegeneration by eliminating what the researchers call "RNA pollution" in aging neurons.

Colorectal cancer (CRC) is the second most common cause of cancer death in the United States and disproportionally impacts people who receive care in under-resourced settings.

Understanding how wounds heal after injury could be a step closer thanks to a new mathematical model developed by researchers at the University of Bristol.

Cedars-Sinai Health Sciences University investigators have developed and successfully tested a new treatment for pregnant women with severe early preeclampsia, a leading cause of premature birth as well as maternal and fetal death.

Delaying hepatitis B vaccination after birth increases infections among newborns and decreases their survival rates and quality of life, according to a new Cornell University study.

Researchers at Center for BrainHealth at The University of Texas at Dallas have identified a specific feature of sleep that helps older adults regulate anxiety overnight - and shown that, as it deteriorates with age, emotional wellbeing deteriorates along with it.

More patients than usual are admitted to hospital Emergency Departments during doctors’ strikes say researchers, who examined changes to patient flows at an NHS Trust in the north-west of England.

Children and young people from deprived areas with mental health conditions are less likely to access mental health services, according to a new study led by experts from the University of Nottingham.

Three clinically available drugs could pave the way for safer and more effective treatments for one of the most aggressive forms of childhood leukaemia, a new study suggests.

Attention-deficit/hyperactivity disorder (ADHD) affects millions of children, yet many go years without a diagnosis, missing the chance for early support that can change long-term outcomes even when early signs are present.

People who live with obesity are 'tagging' a memory of being overweight on a key part of the immune system - leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10 year-long study published in EMBO Reports.

The impact of yoga on heart health in obesity is modest, suggesting it as a complementary approach for improving metabolic outcomes in high BMI populations.

The introduction of HAART for HIV has coincided with a syphilis resurgence, suggesting unintended public health trade-offs from this medical breakthrough.

Researchers updated the global catalogue of human-infective RNA viruses to 239 ICTV-recognised species, incorporating taxonomy, discovery dates, locations, genome links, host range, transmissibility, and transmission routes. The dataset shows that most known human-infective RNA viruses remain strictly zoonotic, while only a minority are endemic in humans or capable of epidemic spread.

A cross-sectional study of 97 women with infertility found that higher vitamin E intake was associated with lower prolactin levels and smaller hip circumference. Riboflavin and calcium intake were linked to higher muscle mass percentage, but the findings are association-based and need confirmation in longitudinal studies.

Essay challenges the scientific validity of the Blue Zones concept and Ancel Keys’ Lipid Hypothesis, arguing that both rest on biased data, weak records, and methodological flaws. The authors say some longevity claims may reflect clerical errors, poverty, and unreliable vital records rather than uniquely healthy lifestyles.

A randomized controlled trial protocol will test whether the cardiometabolic risks linked to ultra-processed foods stem from industrial processing, poor nutrient composition, or both. Using four controlled diets, researchers will separate the effects of UPF content from saturated fat, added sugar, and sodium on LDL cholesterol, insulin resistance, and blood pressure.

As demand for heart transplants continues to far exceed the number of available donor hearts, experts at today's 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) explored a critical question: how should this scarce, life-saving resource be allocated?

By studying and engineering heart tissue in the unique low-gravity environment of space, the laboratory of Arun Sharma, PhD, is uncovering new ways to protect and repair the failing heart.

A new study published in Engineering reveals that obakulactone (OL), a natural tetracyclic triterpenoid isolated from Phellodendri cortex, exerts a therapeutic effect on rheumatoid arthritis (RA) by promoting the degradation of acyl coenzyme A thioesterase 1 (ACOT1) via the ubiquitin‒proteasome pathway and restoring the homeostasis of unsaturated fatty acids.