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Short-term immunosuppressive therapy briefly restores autism-like brain changes in adult mice
A new mouse study led by UCLA Health suggests that inflammation during pregnancy can trigger autism-like changes in offspring, but also that those brain and behavior effects may be rapidly but temporarily reversible in adulthood with a short-term dose of the immunosuppressive drug rapamycin.
Emerging PPAR therapies offer new hope for primary biliary cholangitis
Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatment options need to be developed.
Dormant melanocytes found in vitiligo offer hope for future repigmentation therapies
Vitiligo is an autoimmune disease in which the body's immune system attacks and destroys melanocytes, the cells that produce the skin pigment melanin. Once the melanocytes are gone, the skin turns white, leading to the characteristic skin patches of the disease.
Study reveals regional disparities in Brazilian childhood leukemia mortality
An international study involving LMU found regional differences in childhood lymphoid leukemia mortality across Brazil.
Study finds greater social jetlag linked to a later eating pattern
In a 14-day study of 101 healthy UK adults, greater social jetlag was associated with a later distribution of energy intake, particularly greater late-evening intake among women. The effects were modest, varied by sex and day type, and did not establish whether total daily energy intake differed between groups.
Ancient immune protein C3 boosts cancer immunotherapy within tumors
An ancient molecule that existed long before the blood circulation system evolved, has been found to support cancer immunotherapy.
Spermidine boosts key cellular processes linked to aging in early research
This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational studies link higher dietary intake to lower mortality. However, human trials have produced limited and mixed results, leaving its clinical role in healthy aging unresolved.
Thymulin curbs age-related inflammation and slows breast tumors in mice
Thymulin reduced age-associated inflammatory myeloid cells and slowed breast-tumor growth in aged mice by suppressing NF-κB signaling. The peptide also restored anti-PD-L1 responsiveness in aged mouse models, while human cell and tumor data supported an age-linked inflammatory myeloid profile.
Study reveals bacterial strategy behind antibiotic tolerance and persistence
Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics.
Multiple sclerosis mortality trends underscore need for comprehensive patient care
An analysis of more than 42,000 U.S. deaths linked to multiple sclerosis (MS) found that death rates varied by age, geography, and race and ethnicity, with Black patients dying younger than white patients and high blood pressure emerging as a growing contributor.
Stuffed toys can release short-chain PFAS into saliva, study finds
Researchers tested 18 stuffed toys and found that all released at least one targeted PFAS into artificial saliva under mouthing-relevant conditions, with PFHxA driving much of the variation between products. Modeled intake of the four PFAS covered by EFSA’s group tolerable weekly intake remained below that benchmark, but some high-PFHxA toys had reduced margins of exposure, and water rinsing produced mixed results.
Prolactin activates brain pathway promoting maternal caregiving behavior
New research has found a hormone is responsible for making mothers' interactions with newborns feel rewarding rather than just necessary.
DNA enhancer hubs control cancer genes in prostate tumors
Enhancers are pieces of DNA that act like switches, regulating when genes are turned on and off and how strongly they are activated.
SuperAgers retain exceptional memory through mechanisms beyond genetics
Many people assume that some memory decline is an inevitable consequence of getting older. But a select group of older adults, known as SuperAgers, reach their 80s and 90s while retaining memory performance as good as or better than people in their 50s and 60s.
Exercise may provide limited relief for hip osteoarthritis symptoms
Exercise finds improvements in pain and function may fall short of what patients would notice in daily life, but more studies are needed to make firm conclusions, a new Cochrane review finds.
GLP-1 receptor agonists may increase hair loss risk
Use of glucagon-like peptide-1 (GLP-1) receptor agonists used to treat type 2 diabetes and obesity are associated with an increased risk of hair loss (alopecia) in adults with type 2 diabetes, finds a study published by The BMJ today.
Study links collagen peptides to improved bone health in runners
Collagen is a protein found in skin, hair, nails, tendons, cartilage, and bones. Our bodies naturally produce collagen using the foods we eat. But, in recent years, collagen peptides have gained popularity as a supplement to support joint, hair, skin, and gut health.
Plasma exchange improves recovery in rare inflammatory nerve disease
Plasma exchange can help treat people with a rare inflammatory disease that can cause blindness, according to a systematic review and meta-analysis published on July 22, 2026, in Neurology, the medical journal of the American Academy of Neurology.
Multiple sclerosis deaths occur earlier among Black patients
Black people with multiple sclerosis (MS) die from MS at a younger age than white people, with a peak mortality rate at ages 65 to 74 for Black people and ages 75 to 84 for white people, according to a study published July 22, 2026, in Neurology® Open Access, an official journal of the American Academy of Neurology.
Senolytic drugs rejuvenate blood stem cells in sickle cell disease
Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.




