Rss Feed

Low doses of the investigational medicinal product endoxifen reduce breast density to the same extent as the standard treatment tamoxifen, but without causing such troublesome side effects. This is shown by a new study from Karolinska Institutet published in the Journal of the National Cancer Institute. The results may have implications for future preventive treatment of breast cancer.

Diaceutics, the intelligence and engagement company unlocking the full potential of diagnostic-driven therapies, has released new research revealing a critical shift in precision medicine. Despite major advances in biomarker testing, nearly two-thirds of eligible patients with advanced non-small cell lung cancer (aNSCLC) in the US are still not receiving the most appropriate treatment

The American Academy of Dermatology (AAD) today released results from its annual Practice Safe Sun Survey, revealing many Americans still engage in risky sun behaviors driven by misinformation, social media, and persistent tanning myths despite their concerns about the long term aging effects of sun exposure. In recognition of Skin Cancer Awareness Month (May) and Melanoma Monday® on May 4, the AAD is encouraging the public to practice safe sun to reduce their risk of skin cancer.

New research identifies critical ages for Alzheimer's biomarkers, enhancing screening strategies and understanding neurodegeneration across the aging spectrum.

Short-term nutritional state can reshape T cell metabolism, with post-meal lipid metabolism enhancing T cell metabolic capacity, cytokine production, and persistence after activation. The study identifies triglyceride-rich chylomicrons as key drivers of this effect, suggesting nutritional timing may matter for immune monitoring, vaccination research, and cell-therapy manufacturing.

A Nature study reports a single-molecule GLP-1–GIP–lanifibranor quintuple agonist that targets incretin receptor-expressing cells while activating PPARα/γ/δ pathways. In obese and insulin-resistant mice, the compound reduced body weight, food intake, and hyperglycaemia more effectively than semaglutide or GLP-1R–GIPR co-agonism, while remaining a preclinical finding.

Researchers developed and externally validated integrated polygenic risk scores for eight cardiovascular conditions using large U.S.-based biobank data. The clinically orderable report may help identify inherited cardiovascular risk that traditional clinical markers can miss, although broader prospective validation is still needed.

A gentler treatment for children whose leukemia has come back could boost survival and quality of life, a study led by a UCL academic has found.

New research has shown that GLP‑1 weight-loss drugs deliver protection against heart attacks, strokes and premature death over a sustained period of time.

AgentClinic is a multimodal benchmark that tests clinical AI agents in simulated, dialogue-driven diagnostic settings rather than static medical question-answer formats. The study found that model performance varied sharply by tool use, language, bias, image handling, and patient-agent interactions, highlighting the need for more realistic AI evaluation before clinical deployment.

Methamphetamine (meth) use accounted for nearly 15% of heart attacks for a decade in a northern California study, published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

While high-income countries like Canada could eliminate cervical cancer by 2048 through human papillomavirus (HPV) vaccination and screening, the gap with lower-income countries is widening.

In the years following the COVID-19 pandemic, much has been said about how the lockdowns created conditions for dual-parent families to spend more time at home with their children.

T cells are crucial components of our immune system, serving as critical protectors against infection and disease.

The scientific consensus is that vaccinations are neither causally nor statistically linked to autism. The US health authority CDC changed its official communication on this matter and instead emphasized a connection could not be scientifically ruled out.

CAR T-cell therapy has transformed the treatment of hematologic malignancies, yet many patients do not achieve lasting benefit – often because the infused cells fail to expand or persist.

Researchers at the Garvan Institute of Medical Research have uncovered a critical mechanism driving inflammation in mevalonate kinase deficiency (MKD), a rare but devastating autoinflammatory disorder.

During brain development, neurons can regulate their movement until they reach their final destination thanks to a "molecular switch" involving the protein Teneurin 4 (Ten4).

Epilepsy is best known for seizures, but many people with the condition also experience much more frequent and subtler disruptions.

Infants who grew up in early child care institutions in the 1950s have a much shorter life expectancy than the general population, a long-term study of individuals in Zurich has shown