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Intermittent fasting is unlikely to lead to greater weight loss in overweight or obese adults than traditional dietary advice or doing nothing, a new Cochrane review finds.

A new study has identified an association between consumption of drinks containing a high amount of sugar and anxiety symptoms in adolescents.

A randomized crossover weight loss trial in adults with overweight or obesity found that higher protein big breakfasts improved satiety, while higher fibre breakfasts produced slightly greater weight loss and more favourable gut microbiota markers. Both diets improved metabolic biomarkers, but microbiota changes reflected surrogate gut health indicators rather than direct clinical outcomes.

Higher intakes of total, processed, and unprocessed red meat were associated with greater odds of diabetes in a nationally representative sample of US adults. Statistical substitution models suggest replacing red meat with plant proteins, poultry, dairy, or whole grains may be linked to lower diabetes odds, though causality cannot be inferred.

This mini-review synthesises evidence showing that adenosine-to-inosine RNA editing plays an important regulatory role in cardiovascular development, cellular homeostasis, and disease biology. It highlights emerging links between dysregulated RNA editing and cardiovascular conditions while outlining biomarker potential and reversible RNA-editing therapeutic strategies that remain under investigation.

Greater adherence to healthful plant-based dietary patterns was associated with lower breast cancer incidence and reduced all-cause mortality among women with breast cancer in large prospective cohorts. Specific micronutrients showed differential associations with cancer risk and survival, though findings remain observational and not causal.

Adult obesity is associated with a substantially higher risk of severe hospital-treated or fatal infections across multiple pathogens, with risk increasing as obesity severity rises. Global modelling suggests roughly one in ten infection-related deaths worldwide may be attributable to adult obesity, although causality cannot be confirmed.

This narrative review examines how micro- and nanoplastics may contribute to oxidative stress, inflammation, and metabolic dysfunction, including potential links with diabetes. It highlights plant-derived nutrients that activate the Nrf2 pathway as a possible strategy to enhance cellular stress resilience, although most evidence remains preclinical.

Lung cancer in never smokers is an increasingly recognized global health issue with distinct biological drivers, environmental risk factors, and genetic susceptibilities. Improved risk modelling, targeted screening strategies, and preventive approaches are needed to enable earlier detection and reduce mortality in this growing patient group.

Intranasal boosting after prior intramuscular COVID vaccination induced strong mucosal IgA responses in a small human cohort. These antibodies showed markedly enhanced neutralising activity against Omicron variants and evidence of immune memory reprogramming toward mucosal protection.

Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found.

Recent global crises have exposed the limits of a universal mortality threshold for declaring famine-an approach that can obscure how famine actually unfolds across different populations.

After high-profile water crises like the one in Flint, Michigan, some Americans distrust the safety of tap water, choosing to purchase drinking water from freestanding water vending machines or kiosks.

New research reveals how attachment insecurity and materialistic values fuel 'phubbing' in romantic relationships.

Cell and gene therapies, or CGT, have come a long way since they were first introduced. In the last few decades, both cell therapy -- the transplantation of living cells -- and gene therapy -- the use of genetic material to modify cell functions -- have been increasingly incorporated into clinical practice.

The ventral tegmental area (VTA) is a key brain region for dopamine production and the regulation of reward-related behaviors.

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy, affecting a significant proportion of patients who develop drug-resistant epilepsy.

Chronic diabetes mellitus is marked by hyperglycemia and metabolic dysfunction, increasing the risk of complications such as nephropathy.

A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together with the Schief Lab at Scripps Research Institute, has uncovered a previously unrecognized mechanism that shapes how immune cells are selected during an immune response.

"Like father, like son? Can parenting styles break the intergenerational pattern of alcohol and drug use?" A group of Brazilian researchers analyzed data on the behavior of 4,280 adolescents and their guardians based on this question, arriving at two important conclusions.