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Integrated DNA Technologies and Aldevron launch new Cas9 mRNA solutions to accelerate path from gene editing research to development
Danaher companies Integrated DNA Technologies (IDT), a global leader in genomics, and Aldevron, a premier manufacturing partner for DNA, RNA, and protein, today announced the launch of research grade S.p. Cas9 mRNA in wild type and SpyFi™ high-fidelity formats.
Diaceutics launches Precision for All Strategic Collaboration at Fierce Pharma Week 2026
Intelligence and engagement company, Diaceutics, is bringing together senior voices from across the biopharmaceutical industry at the Precision for All Strategic Collaboration, launching at Fierce Pharma Week 2026.
Some food manufacturers could capture major nutrition and environmental gains by changing surprisingly few products
Researchers assessed the nutritional quality and environmental impacts of product portfolios from 44 major UK food and beverage manufacturers, covering 51.5% of the retail market. Their modelling showed that targeted changes to existing product lines could capture a substantial share of the potential nutrition and environmental gains for some manufacturers, although broader food-system changes would still be required to meet national and societal targets.
Big Picture Bio founded to identify, design and optimize promising cancer combination therapies
Big Picture Bio Ltd., has been founded to identify, design and optimize promising cancer combination therapies, using a generative world model to understand how tumors, immune cells and surrounding tissue interact across disease sites and patient subgroups.
Quotient Sciences proprietary AI-enhanced solution optimizes formulation in clinical study
Quotient Sciences, a global integrated CRDMO (contract research, development and manufacturing organization), today reported interim results from a clinical study in which a proprietary artificial intelligence (AI) algorithm selected modified-release formulation compositions and doses during the trial.
Better fitness was linked to healthier brain structure, but not better memory
Researchers studying 353 cognitively unimpaired adults aged 60 to 94 found that higher muscular capacity was associated with lower basal ganglia perivascular space volume, while greater aerobic fitness was associated with greater gray matter volume and medial temporal lobe thickness. Fitness was not directly associated with global cognition or episodic memory, and evidence for cognitive reserve was limited, although VO₂max explained additional variation in delayed verbal memory beyond tau burden.
Study identifies two opposing molecular patterns in autism models
Autism spectrum disorder (ASD) is associated with more than 1,200 risk genes, raising a fundamental question: Do these diverse genetic changes affect the brain in entirely different ways, or do they converge on shared biological mechanisms?
Sex-specific biological clocks reveal how aging differs across the body in women and men
Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns. Brain aging clocks were linked to progression from mild cognitive impairment to Alzheimer’s disease in both sexes and to sex-dependent cognitive trajectories among solanezumab-treated A4 participants, while the authors stressed that sex-pooled and sex-interaction models remain complementary approaches.
Exercise-based cardiac rehabilitation offers lasting heart health benefits
Exercise-based cardiac rehabilitation reduces hospital admissions by a third and heart attack risk by more than a quarter, as well as remaining beneficial in the long term, a new Cochrane review finds.
Eight-weekly HIV injections prove more effective than daily tablets for young people
Young people living with HIV manage their condition better when their antiretroviral therapy is given by injections every eight weeks, rather than in the form of daily tablets, according to the results of a trial in Africa led by UCL (University College London) researchers.
Researchers mine cobra toxins to uncover a membrane-disrupting antimicrobial peptide
Researchers combined toxin sequence mining with machine learning and deep-learning prediction tools to identify and experimentally test 14 antimicrobial peptide candidates derived from cobra cardiotoxins. Most candidates showed limited antibacterial potency, while CTX-p5 displayed moderate membrane-disrupting activity, revealing both the potential and current limitations of computationally guided venom peptide discovery.
Being active may not tell the whole story when it comes to weight gain
A five-year study of 2,606 young and early-midlife Finnish municipal employees examined how leisure-time physical activity and sedentary behavior were associated with gaining at least 10% of baseline body weight. About 24% of women and 12% of men experienced major weight gain, with the analysis pointing to the importance of considering activity and sedentary time together.
Can maternal diet prevent infant food allergy? A large trial puts eggs and peanuts to the test
A large Australian randomized trial of 2,137 pregnant women tested whether substantially increasing egg and peanut consumption during pregnancy and breastfeeding could prevent food allergy in infants with a strong family history of allergic disease. Higher maternal intake did not significantly reduce IgE-mediated egg or peanut allergy at 1 year, although the lower-than-expected allergy rate limited statistical power and the results could not exclude a clinically important benefit.
Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system
One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but that some tumors give them too little to see.
Study identifies powerful inherited risk factor for lung cancer
A rare inherited mutation in the Epidermal Growth Factor Receptor (EGFR) gene is associated with a 25-fold increased risk of lung cancer, according to a study by investigators at Dana-Farber Cancer Institute and 23andMe Research Institute.
Study highlights drop in harmful medication use among adults with cognitive disorders
Adults 65 and older with cognitive disorders such as dementia, are more likely to suffer negative effects from drugs that treat central nervous system conditions including anxiety, sleep problems and psychosis.
Maternal depressive symptoms linked to higher infant mortality risk
Infants born to mothers with depressive symptoms immediately after delivery had a substantially higher risk of dying before their first birthday, according to researchers involved in a Rutgers-led study of more than 414,000 births in New Jersey.
ACC Latin America 2026 studies highlight sex and regional disparities in heart attack care
disparities in ST-segment elevation myocardial infarction (STEMI) management and outcomes across Latin America, focusing on women as a higher risk, yet underrepresented, patient group.
US health officials knowingly relied on flawed vaccine safety algorithm
US health officials knowingly relied on a compromised algorithm to detect signals of harm from mRNA covid-19 vaccines and silenced efforts to fix it, finds an investigation published by The BMJ today.
Weill Cornell Medicine receives $17.4 million grant to shorten tuberculosis treatment
Researchers at Weill Cornell Medicine have received a $17.4 million, five-year grant from the National Institute of Allergy and Infectious Diseases to discover new approaches to shorten tuberculosis (TB) treatment, potentially making it easier for patients to complete therapy.




