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Ketamine boosts neuroplasticity through microglia in female brains
Doctors use ketamine on patients as general anesthesia before surgery. They also prescribe it in low doses for pain management, and more recently, it's been used for treatment-resistant depression where other drugs have failed.
Study offers a potential strategy to make nanoparticle-based cancer drugs more effective
A new study led by researchers at The University of Texas MD Anderson Cancer Center has identified a way to reshape the gut microbiome that can enhance the delivery of certain chemotherapies to tumors, offering a potential strategy to make nanoparticle-based cancer drugs more effective.
Secondhand smoke alters tooth enamel development in early life
Exposure to secondhand cigarette smoke during the first days of life can cause changes in tooth enamel mineralization without causing visible changes to the teeth.
Natural compounds could combat drug-resistant malaria and babesiosis
As parasites become increasingly resistant to existing drugs, researchers at the University of California, Riverside are working to develop a new generation of treatments for two serious infectious diseases: malaria and babesiosis.
Arginine boosts immune defenses against cancer and viral infections
The amino acid arginine helps to keep the human body humming, most notably by synthesizing proteins that carry out a range of cellular processes.
Engineered extracellular vesicles counter deadly cytokine storms in mice
The COVID-19 pandemic highlighted some severe consequences of unchecked respiratory disease, including cytokine storm.
TRF2 protein preserves muscle stem cell identity and regeneration
A protein best known for protecting the ends of chromosomes also helps muscle stem cells preserve their identity and repair damaged tissue, according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania.
Immune cell navigation breakthrough offers hope for better anti-inflammatory drugs
A scientific collaboration between the University of Bath (UK) and the UMass Chan Medical School (USA) have determined how a specific type of white blood cells, called neutrophils, move through the body.
Midpregnancy herbicide exposure linked to increased preterm birth risk
Exposure to a widely used herbicide during the middle months of pregnancy may increase the chance of giving birth too early, before 37 weeks, a new study shows.
New mechanism linked to septic heart injury protection uncovered
Sepsis triggers widespread inflammation, circulatory failure and metabolic stress, and cardiac dysfunction is a common complication associated with sharply poorer outcomes.
Consuming less protein could have greater health benefits and extend lifespan
Protein-fortified foods are popping up everywhere, from cereal and coffee to even protein water. But a new review covering over 350 papers on protein restriction and aging-publishing July 31 in the Cell Press journal Cell Press Blue-suggests that consuming less protein could have greater health benefits and could, in some cases, extend lifespan.
Generational shifts drive growing clinical workforce shortages in healthcare
If it feels harder to keep the same doctor, you're not imagining it. Healthcare leaders say retirements, burnout and changing workforce expectations are making it complicated to keep experienced clinicians in place.
Scientists map protective cell networks hiding dormant breast tumor cells
Researchers at the MRC Laboratory of Medical Sciences (LMS), Imperial College London and UCL Genetics Institute have created a detailed map of cells within breast tumors and identified distinct neighborhoods of proliferating and dormant cells.
Researchers propose new framework to define clinical obesity
A new approach to defining obesity could help physicians better determine which patients need more intensive treatment by focusing on the effects of excess adiposity on organs and tissues rather than relying primarily on whether a person meets a set of metabolic risk thresholds.
Genetic variants interact to increase early-onset atrial fibrillation risk
An estimated 10 million Americans have atrial fibrillation (AFib), according to the National Institutes of Health's National Heart, Lung, and Blood Institute.
URI professor wins $1.5M grant to study cerebral amyloid angiopathy
A $1.5M grant has been awarded to William Van Nostrand, co-executive director of the University of Rhode Island's George & Anne Ryan Institute for Neuroscience and professor of pharmaceutical and biomedical sciences in the URI College of Pharmacy, to study cerebral amyloid angiopathy (CAA), a disease prevalent in the elderly population and commonly found in patients with Alzheimer's disease.
Accumulation of somatic mutations drives vascular damage in people with progeria
Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder that causes remarkable premature aging.
Exposure to fungicides and insecticides alters onset of puberty in girls
The study, which tracked more than 500 Spanish girls between the ages of 7 and 10, links the presence of certain fungicides in urine to early menarche and that of the insecticide chlorpyrifos to delayed menarche, highlighting the impact of pesticides on pubertal development.
Soy lysolecithin reduces salt-induced hypertension and cognitive decline
High salt (HS) intake is a major global health concern, closely linked to hypertension and growing evidence of cognitive and emotional decline.
Tailored online nutrition tools empower frail older adults
While existing digital health tools can provide valuable information to offset poor nutrition, older adults with pre-frailty and frailty want to engage with these tools easily, to support their autonomy, dietary self-management and healthy aging.




