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Researchers compared beliefs from 887 US adults with modeled lifespan trajectories from 166,971 participants across eight longitudinal studies. Population-average Big Five traits changed as much as or more than many health, financial, psychological, and social measures, despite people perceiving personality as unusually stable.

Researchers found that regular meals, Mediterranean diet adherence, sufficient sleep, and limited television viewing were independently associated with better grades among 974 adolescents. Meeting more healthy lifestyle recommendations was consistently associated with stronger performance across first, second, and third languages.

Researchers used single-molecule and super-resolution imaging to profile protein aggregates across six brain regions from 29 post-mortem donors, detecting high-intensity phosphorylated tau aggregates in the Parkinson’s disease putamen despite negligible conventional tau staining. PD cases with dementia showed greater tau burden than those without dementia, while the assay did not detect a PD-specific population of nanoscopic alpha-synuclein aggregates.

Researchers developed Oncoformer, a multimodal transformer that analyzes longitudinal health records and chest X-rays to classify cancer, predict diagnoses up to one year in advance, infer tumor stage, and forecast treatment response and recurrence risk. Validation across large independent cohorts showed strong performance, although prospective trials in diverse, average-risk populations are needed before clinical use.

Scientists at the Fralin Biomedical Research Institute at VTC have discovered how an experimental therapy can help brain cells overcome the effects of a disease-causing genetic deletion.

A study co-led by investigators at Mass General Brigham reveals that mobile addiction services can be implemented across multiple organizations and communities to bring addiction treatment, harm reduction services and basic healthcare directly to people who use drugs, especially those disconnected from traditional care.

Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts that power our other organs, our heart cells evolved to be extremely efficient and resilient.

A father's diet can affect his children's health and body composition before they are even conceived. A study of 43 triads of fathers, mothers, and newborns treated in the public healthcare system of Ribeirão Preto in the state of São Paulo, Brazil, demonstrated this.

Glioblastoma is an aggressive brain tumor that infiltrates deep into the surrounding brain tissue. Even after surgery, tumor cells remain in the brain and the tumor recurs.

A recent study revealed that periodontitis reprograms bone marrow neutrophils through a Chac2-driven glutathione metabolic pathway, promoting a highly inflammatory N1 state that fuels systemic inflammation.

Osteoporosis is one of the most common age-related bone diseases, affecting millions of people worldwide and increasing the risk of fractures, disability, and reduced quality of life.

New research led by scientists at La Jolla Institute for Immunology (LJI) and University of Liverpool (UOL) provides the first comprehensive look at how a hidden immune cell army defends the vast, vulnerable tissue of the human lungs.

Children who attend preschool before starting school are significantly more likely to arrive ready to learn, according to a major Curtin University study of more than 123,000 Western Australian children.

The Translational Genomics Research Institute (TGen), part of City of Hope, today announced it has been selected as part of a national team to join the Collaborative Research Network (CRN), an international, multi-institutional initiative focused on addressing high-priority research questions in Parkinson's disease.

University of Missouri researchers have identified a simple, effective way to improve quality of life. A new study found that maintaining a consistent daily routine can reduce physical pain and ease symptoms of depression, demonstrating how everyday habits can have a meaningful impact on well-being, particularly for older adults with insomnia.

Emergency departments across the country face a common challenge: how to reduce long wait times without adding more beds, hiring more staff or expanding facilities.

Infants use eye contact with speakers to work out what to pay attention to and synchronize their brainwaves, helping them learn language, scientists in Cambridge and Singapore have shown.

A randomized clinical trial conducted in India by Indian and Norwegian researchers demonstrates that an integrated intervention package improves growth and neurodevelopment in babies born to small, so-called Small-for-Gestational Age (SGA) infants.

What makes a diet healthy-or not? According to a new study, nutritional quality matters more than processing level when it comes to long-term health.

A study led by Dr. Zeynep Seda Albayrak from Koç University identified three distinct psychosocial profiles among 158 adolescents receiving psychiatric outpatient care, each associated with different patterns of digital technology use.