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Impaired spatial orientation found in older adults at risk for Alzheimer’s disease
Individuals with an increased risk for dementia due to Alzheimer's disease can have impaired spatial orientation skills.
Loneliness linked to higher NHS healthcare costs and poorer health in the UK
Lonely people incur an extra £850 in annual healthcare costs to the NHS, as well as experiencing worse mental and physical health
Dual antiplatelet therapy shows no benefit over aspirin after CABG in patients with acute coronary syndrome
Dual antiplatelet therapy (DAPT) was not more effective than aspirin alone for the prevention of major adverse cardiovascular events and increased major bleeding in patients with acute coronary syndrome (ACS) who underwent coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session today at ESC Congress 20251 and simultaneously published in New England Journal of Medicine.
Stopping oral anticoagulation reduces risk after successful atrial fibrillation ablation
Discontinuing oral anticoagulation (OAC) therapy resulted in a lower risk of a composite of stroke, systemic embolism or major bleeding than continuing OAC therapy in patients who had successful ablation for atrial fibrillation at least 12 months previously, according to results from a late-breaking trial presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in The Journal of the American Medical Association.
No clear benefit from surgical left atrial appendage occlusion in non-AF patients after valve surgery
No benefit in terms of prevention of ischemic stroke, transient ischemic attack and cardiovascular mortality after 1 year was observed when surgical left atrial appendage occlusion was performed in high-risk non-atrial fibrillation patients after valvular surgery, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.
Study finds sex differences in schizophrenia and bipolar disorder
Schizophrenia and bipolar disorder are serious mental illnesses that affect both males and females, but research in Acta Psychiatrica Scandinavica indicates that sex may influence the characteristics and course of these conditions.
Genetic variant disrupts brain’s cleanup crew increasing Alzheimer’s risk
A Nature study published today and led by researchers at the University of South Florida's USF Health Byrd Alzheimer's Institute pinpoints how a genetic variant disrupts microglia - the brain's "cleanup crew" - increasing the risk of Alzheimer's disease.
New protein-based therapeutic tool could change the way we treat diseases
A team of scientists at Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS) has created a protein-based therapeutic tool that could change the way we treat diseases caused by harmful or unnecessary cells.
Dental care gaps affect children with sickle cell disease in Michigan
Children with sickle cell disease are more likely to have dental problems - but fewer than half of those covered by Michigan Medicaid got dental care in 2022, according to a new study.
Long-term benzodiazepine use linked to poor sleep quality in older adults
Long-term use of benzodiazepine and related drugs has been linked to poorer quality sleep in older adults with insomnia.
Sugar-coated nanoparticles offer new hope for treating triple-negative breast cancer
Triple-negative breast cancer is particularly aggressive and difficult to treat; but recent research may offer a new way to target the often-deadly disease.
First complete brain activity map reveals how decisions are made
The first complete activity map of the brain has been unveiled by a large international collaboration of neuroscientists.
Flooding from Hurricane Sandy raises heart disease risk years later
Although the material damage from 2012's Hurricane Sandy may have been repaired, the storm left a lasting impact on cardiovascular health, according to new findings from Weill Cornell Medicine and New York University researchers.
Researchers uncover a promising new therapeutic target for Barth syndrome
Researchers at The Hospital for Sick Children (SickKids) have uncovered a promising new therapeutic target for Barth syndrome, a rare genetic condition with no current cure.
Chronic stress and fatty diet disrupt brain-liver circuit leading to diabetes
This study discovered a circuit in the brain that connects stress with increased glucose and therefore may link stress to type 2 diabetes. In stressful situations, this circuit from the amygdala to the liver naturally provides a burst of energy.
Home-based hypertension care improves blood pressure control in rural South Africa
Home-based hypertension care led to reductions in systolic blood pressure and improvements in hypertension control in South Africa, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in the New England Journal of Medicine.
Playing joyful music helps ease motion sickness symptoms
Scientists studying ways of improving motion sickness have found that playing different types of music may help people recover more effectively.
Novel ablation approach improves outcomes in patients with persistent atrial fibrillation
Adding digital twin-guided ablation to a standard ablation technique improved outcomes in patients with persistent atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.
Ablation methods equally effective for drug-resistant paroxysmal atrial fibrillation
Pulsed field ablation did not have superior efficacy to radiofrequency ablation in patients with drug-resistant paroxysmal (intermittent) atrial fibrillation, according to results from a late-breaking trial presented in a Hot Line session today at ESC Congress 2025.
Can listening to sad music heal a heartbreak?
Neurotic individuals may use maladaptive music listening to cope with breakup distress, leading to intensified negative emotions and mental health challenges.
