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More steps cut chronic disease risk but cannot fully undo long sitting
Research shows higher daily step counts can mitigate risks of chronic diseases linked to prolonged sitting, emphasizing the need to reduce sedentary time.
Talc not contaminated with asbestos shows no link to cancer
In a systematic review and meta-analysis, researchers found that occupational exposure to talc that is not contaminated with asbestos is not associated with an increase in the risk of lung cancer, mesothelioma, or laryngeal cancer.
Revvity unveils its Signals BioDesign offering to advance biologic research workflows
Revvity, Inc. announced that its Revvity Signals Software business is launching Signals BioDesign™, a cloud-native molecular cloning solution that streamlines biologics research workflows.
When omega-3 may help mental health and when they may not
Investigating omega-3 fatty acids, this review highlights their impact on mental health, inflammation, and the potential for therapeutic use in disorders.
Large US study finds never-married adults face higher risk for most major cancers
A large US population-based study found that never-married adults had higher cancer incidence than ever-married adults across most cancer types, with the largest disparities seen in older adults and in Black men. The pattern was especially strong for HPV-related, tobacco-related, and several reproductive cancers, suggesting marital status may act as an important social marker of cancer risk.
DARC-NESS model offers insights into persistent nightmares in children
Recently published research from the University of Oklahoma and the University of Tulsa proposes a new model to explain why nightmares can persist over time in children and how therapy can be designed to break that cycle.
Two new TB vaccines show safety but limited protection
Two new vaccines to prevent tuberculosis (TB) are safe for use in adults and children, but they do not offer protection against all forms of TB, finds a large trial from India published by The BMJ today.
Quitting tobacco could boost incomes of millions of households in India
Quitting tobacco could give a major economic uplift to the incomes of more than 20 million households in India, suggests an economic analysis published in the open access journal BMJ Global Health.
Study finds nutritional risks in users of GLP-1 drugs
Adults with overweight or obesity taking the new generation of weight loss drugs semaglutide and tirzepatide tend to eat significantly less, leaving them vulnerable to nutritional deficiencies, according to one of the first real-world studies to examine dietary behavior in people using glucagon-like peptide-1 receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) dual agonists RAs (collectively referred to as GLP-1 RAs) with the help of an AI-powered nutritional tracking app.
Early childhood habits shape physical activity levels in adolescence
The numbers are sobering: nearly 80 per cent of the world's teenagers don't get enough physical activity, according to the World Health Organization.
Study identifies four radiomic profiles linked to sarcoidosis severity
Researchers have identified a new method for analyzing chest CT scans that may help physicians better understand the different forms of sarcoidosis, a complex inflammatory lung disease that affects more than 150,000 people in the United States.
Higher optimism may lower dementia risk in older adults
Higher optimism in adults aged 70 and older was associated with a lower risk of developing dementia over up to 14 years of follow-up in the Health and Retirement Study. The association remained after adjustment for demographic factors, depression, health conditions, smoking, and physical activity, although the study was observational and cannot prove causation.
Wildlife trade increases risk of disease transmission to humans
From lemurs to fennec foxes, wild animals are bought and sold around the world-legally and illegally, dead and alive-including as pets, for food and for traditional medicinal uses.
IBS diagnosis gaps persist across racial and gender groups in the U.S.
A national survey study led by UCLA Health and Cedars-Sinai Medical Center found significant disparities in how irritable bowel syndrome, or IBS, is diagnosed across sex and racial groups in the U.S., with men and Black patients considerably less likely than women and white patients to receive a formal diagnosis.
High prenatal PFAS exposure linked to increased childhood asthma risk
PFAS (perfluoroalkyl and polyfluoroalkyl substances) are a large group of synthetic substances that can be found in many products and foods, including firefighting foam.
Genetic variants may help explain who loses more weight and who gets side effects on GLP-1 drugs
A large 23andMe-based GWAS found that common variants in GLP1R and GIPR help explain why some people lose more weight or experience more nausea and vomiting on GLP-1 drugs. The findings suggest genetics may eventually help predict who responds best to semaglutide or tirzepatide and who is more likely to develop side effects.
Targeted diet helps reprogram aggressive neuroblastoma in mice
Researchers highlighted how an arginine- and proline-restricted diet combined with eflornithine reprogrammed MYCN-driven neuroblastoma in mice, pushing tumor cells out of the cell cycle and toward differentiation. The commentary argues that this metabolism-to-translation link could open a new path for testing targeted dietary strategies alongside cancer drugs in future clinical studies.
New 3D organoid model advances pediatric glioma research and treatment
A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor of the central nervous system that often occurs in children.
New combination therapy shows safer approach to treating Alzheimer’s disease
A new study finds that combining the current medications for Alzheimer's disease with small molecules derived from micronutrients found in grapes, berries, peanuts and turmeric is a safer and more effective way to treat the disease.
Study finds gap in school-based dental care participation
Children who don't go to the dentist are less likely to participate in school-based cavity prevention programs, according to research published in JAMA Network Open.




