Feed aggregator

Pitolisant, a histamine H3 receptor inverse agonist, improved recognition memory, working memory performance, and reinforcement learning in healthy adults. The findings suggest that histamine helps shape how the brain stabilizes new memories, accumulates evidence for decisions, and avoids overreacting to negative outcomes.

Depression, anxiety and sleep disorders are among the conditions often treated with antidepressant drugs. Yet, up to 90% of these drugs pass through the body into wastewater.

In a study published in the Liver Transplantation journal by the American Association for the Study of Liver Diseases, Mayo Clinic researchers found that a new proactive treatment protocol for alcohol use disorder after liver transplant resulted in a 0% heavy alcohol relapse rate among patients who followed the protocol, compared with a historical relapse rate of approximately 25%.

For people with epilepsy, living in counties that are more rural was associated with poorer health outcomes than for people living in more urban counties, according to a study published June 3, 2026, in Neurology, the medical journal of the American Academy of Neurology.

When looking at genetic variants in a person's DNA that predispose them to disease, a new study has found having a higher number of genetic variants for increased pulse pressure is associated with a small, increased risk of dementia as a contributing cause of death.

Constipation was associated with approximately twofold higher odds of depression in a meta-analysis of 18 observational studies involving 730,263 participants. The findings support integrated gastrointestinal and mental health assessment, especially for adolescents and young adults, while emphasizing that causality cannot yet be established.

The University of Mississippi-led study, published in Frontiers in Public Health, offers health care and government leaders a new tool for targeting HIV-related support where the need is highest.

Air pollution does not have to exceed federal limits to potentially harm human health, according to a new review published in Environmental Pollution.

A new study by researchers at UC Davis Health and Kaiser Permanente found that higher exposure to very small air pollution particles (PM2.5) over a 17-year span was associated with lower semantic memory.

A new global study has found that people without access to clean drinking water are significantly more likely to experience food insecurity and food safety threats, underscoring the urgent need for coordinated global action to address these issues together.

Pregnancy acts as a natural cardiovascular stress test, revealing hidden heart disease and identifying women at higher long-term risk after complications such as preeclampsia, gestational diabetes, and preterm birth. The review highlights major evidence gaps in cardio-obstetric care and calls for stronger postpartum screening, dedicated women’s health clinics, and better inclusion of reproductive-age women in research.

A large retrospective cohort study of 111,646 overweight or obese women found that GLP-1 agonist exposure was associated with lower breast cancer incidence. After propensity-score matching, GLP-1 exposure was linked to nearly 30% lower odds of breast cancer, but the authors stress that randomized trials are needed before these drugs can be considered for prevention.

A new study developed a mineralized DNA hydrogel that combines immune regulation with sustained bone regeneration.

An international team of researchers from Europe and Australia will contribute to MICRO-NEST, a €6 million Horizon Europe project applying innovative approaches to identify markers of autism in children born before 37 weeks of gestation.

A new Tulane University study challenges a long-standing assumption in heart care: that being female automatically increases stroke risk for patients with atrial fibrillation, a common condition that causes the heart to beat irregularly.

People with disabilities continue to face major barriers when seeking oral health care, according to new research that explored the perspectives of patients, caregivers, and healthcare professionals in different countries.

Psychedelic drug experiences are among the most fascinating but mysterious journeys of the human mind.

Ferroptosis has become a promising area in cancer research because it may provide a way to target tumor cells that evade other better-known forms of programmed cell death, such as apoptosis and necroptosis.

Across partisan lines, Americans broadly believe ultraprocessed foods are addictive and harmful – expressing attitudes strikingly like those that spurred regulation of the tobacco industry, new Cornell University-led research finds.

Current therapies for rheumatoid arthritis rely on sustained immunosuppression rather than restoration of immune tolerance, with off-drug remission remaining rare.