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Targeting a sugar metabolism pathway offers hope for treating rare and aggressive childhood cancer
A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to improved treatments for patients.
Faulty glucose transport weakens insulin release in Type 2 diabetes
Just as smart traffic management ensures smooth vehicular movement during peak hours, our body relies on a molecular traffic system to manage the surge in glucose levels after a meal.
Researchers investigate how citrus bioflavonoid naringin could reduce inflammation and heart risk
Researchers reviewed 62 studies on naringin, a citrus flavonoid, and found strong preclinical evidence for its cardioprotective effects, including improved endothelial function, reduced oxidative stress, and protection against myocardial injury.
Discovering the brain’s internal compass through virtual reality
Zhengang Lu and Russell Epstein, from the University of Pennsylvania, led a study to explore how people maintain their sense of direction while navigating naturalistic, virtual reality cities.
Mediterranean diet success looks different for women and men, study of 4,000 adults reveals
A Mediterranean lifestyle survey of over 4,000 adults across seven countries found that while men and women scored similarly on overall adherence, they achieved this through different patterns of diet, exercise, and well-being. Tailored strategies may be needed to support gender-specific improvements in health behaviors.
Ultra-processed foods undermine diet quality in Mediterranean youth, study shows
A large study across five Mediterranean countries found that children and adolescents who consumed more unhealthy ultra-processed foods (UPFs) had significantly poorer diet quality. Daily UPF intake was especially linked to lower adherence to the Mediterranean diet and reduced compliance with dietary guidelines.
Fucosylation emerges as a key player in digestive inflammatory diseases and cancers
Fucosylation, a crucial post-translational modification, has emerged as a significant factor influencing digestive inflammatory diseases and cancers.
New nanoparticle drug delivery system targets the spleen for precise lupus treatment
With a $1 million Impact Award from the U.S. Department of Defense, Tianfu Wu, a University of Houston biomedical engineer, is developing a method to send medication directly to the spleen where certain immune cells cause the disease known as lupus, or Systemic Lupus Erythematosus.
Community-driven ADHD initiative leads to better outcomes for children
Innovative intervention delivered by trained community health workers – meaning nonclinical personnel with deep knowledge of the community – increased treatment utilization among participating families with children who have ADHD, according to a pilot study published in the Journal of Attention Disorders.
Mitochondrial metabolite glutathione plays key role in breast cancer metastasis
The mitochondria may be the powerhouse of the cell, but mounting evidence suggests this organelle is also a driving force behind cancer.
Prenatal exposure to common insecticide linked to brain changes and poor motor skills in children
A new study reports evidence of a link between prenatal exposure to the widely used insecticide chlorpyrifos (CPF) and structural abnormalities in the brain and poorer motor function in New York City children and adolescents.
Over-the-counter oral birth control pill improves access to contraception
Two years ago, the Food and Drug Administration approved the sale of an over-the-counter birth control pill for the first time in the United States without a prescription.
Vaccines trigger immediate changes in lymph node tissue landscape
Vaccines trigger a notably rapid response in the stromal cells of draining lymph nodes within the first hours after administration.
Polβ enzyme found to protect developing brain from harmful DNA mutations
A research group led by The University of Osaka has discovered that the DNA repair enzyme Polβ plays a crucial role in protecting the developing brain from harmful mutations.
RNA quality control protein PELOTA found to slow aging and extend lifespan
As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases.
Inactivation of stress pathway allows ER+ breast cancer cells to evade treatment
A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade treatment.
Endoplasmic reticulum controls cell movement to repair tissue gaps
The body's cells change their shape to close gaps such as wounds – with part of the cell flexing depending on the curve of the gap and the organization of cell-internal structures, a new study reveals.
New molecule shows promise in treating acetaminophen-induced liver injury
Acetaminophen is one of the most common painkillers and is found in hundreds of different medications. While safe at recommended doses, acetaminophen overdose is the leading cause of acute liver injury in the U.S.
Fasting does not have the same effect on all body types, study suggests
While fasting has become a popular trend, particularly for people who hope to lose weight, new UBC Okanagan research suggests fasting does not have the same effect on all body types.
Highly sensitive individuals more prone to mental health challenges
The meta-analysis of 33 studies, the first of its kind, looked at the relationship between sensitivity and common mental health problems such as depression and anxiety.




