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In a groundbreaking new study published in Nature Communications, researchers from the Linda Crnic Institute for Down Syndrome (Crnic Institute) at the University of Colorado Anschutz discovered important differences in the physiological changes observed in over 300 individuals with Down syndrome across the lifespan.

Changes in vision are often a common sign of aging. If you sit in a dimly lit restaurant with anyone over the age of 60, you'll likely hear the person say, "Hold on - let me pull out my cell phone. I need more light to read the menu!" But what if we could reverse age-related visual decline?

A new Lancet review proposes a three-wave diagnostic pathway that combines clinical expertise with blood, CSF, and PET biomarkers. This approach aims to deliver earlier, more accurate, and more equitable Alzheimer’s disease diagnosis worldwide.

Researchers using UK Biobank data found that drinking 7–8 cups of coffee, tea, and water per day was linked to the lowest mortality risk. The healthiest mix was a 2:3 balance of coffee to tea, with further benefits over water substitution, but excessive intake (>9 cups) raised cardiovascular risk.

Researchers tested blueberry powder as one of the first complementary foods in human milk-fed infants. The trial found exploratory evidence that blueberries may support healthier gut microbiota development during early life.

Researchers reviewing evidence in NeuroSci show how dietary AGEs and their interaction with RAGE drive oxidative stress, inflammation, and neurodegeneration. They highlight how cooking methods and diet choices could lower AGE burden and protect brain health, while calling for rigorous clinical trials.

Researchers writing in The Lancet review breakthroughs in type 1 diabetes treatment, from immunotherapies that delay onset to stem-cell β-cell replacement and automated insulin delivery. They stress that equitable access, validated surrogate endpoints, and scalable technologies are crucial for lasting impact.

By age 18, three in five U.S. children have enrolled in Medicaid or the Children's Health Insurance Program (CHIP), and two in five have experienced a period of being uninsured, according to a microsimulation model developed by researchers at Harvard T.H. Chan School of Public Health.

Researchers at Karolinska Institutet, together with international colleagues, have identified a protein that is crucial for the TBE virus to infect human cells.

Researchers at the University of Exeter have created a detailed temporal map of chemical changes to DNA through development and aging of the human brain, offering new insights into how conditions such as autism and schizophrenia may arise.

Crimean-Congo hemorrhagic fever virus, or CCHFV, is a biosafety level 4 pathogen and a Category A bioterrorism agent, causing severe viral hemorrhagic fever with mortality rates reaching up to 40%.

In the delivery room, circumstances can turn dire on a dime if the patient starts losing excessive amounts of blood. One minute she seems fine, and the next, vital signs plummet, the patient crashes, and the care team may need to scramble for a blood transfusion or perform surgery.

About 12 million adults in the United States are affected by PTSD, impacting between 4% and 8% of the adult population – and up to 30% of military personnel and veterans.

Researchers from University of California San Diego School of Medicine have found that testing for lipoprotein(a) - a genetic risk factor for heart disease - remains uncommon in the United States, despite modest increases over the past decade.

The diagnosis and medical treatment of Alzheimer's disease, a condition that according to leading researchers in the field should be treated, has now advanced significantly.

A major UK study has revealed that the early warning signs of multiple sclerosis (MS) - including pain, mood changes, and neurological symptoms such as numbness and tingling – may appear years before diagnosis and affect all communities in similar ways.

Scientists have mapped underappreciated scaffolding cells in skin, known as fibroblasts. They show for the first time how fibroblasts go 'rogue' in many different diseases affecting multiple organs – from acne and psoriasis, to rheumatoid arthritis and inflammatory bowel disease.

A study shows that people with higher levels of the protein albumin in their urine are at increased risk of developing dementia. The study, led by researchers at Karolinska Institutet, is published in the scientific journal Journal of Internal Medicine.

Leishmaniasis, a neglected tropical disease prevalent across 90 countries, affects approximately 12 million people worldwide, with 350 million more at risk of infection.

The trillions of microbes that live in the human gut may play a bigger role in health than previously thought, according to a new research by the University of Hawaiʻi at Mānoa.