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Menopause hormone therapy not linked to dementia risk in women

Rss Feed - Mon, 12/22/2025 - 22:04
A major review of prior research has found no evidence that menopause hormone therapy either increases or decreases dementia risk in post-menopausal women, in a new study led by University College London (UCL) researchers.

THC products provide small improvements in pain but carry side effects

Rss Feed - Mon, 12/22/2025 - 22:00
A new systematic evidence review finds that cannabis products that carry relatively high levels of the psychoactive compound tetrahydrocannabinol, commonly known as THC, may provide short-term improvements in pain and function.

Early brain connectivity predicts recovery after traumatic brain injury

Rss Feed - Mon, 12/22/2025 - 21:58
After traumatic brain injury (TBI), some patients may recover completely, while others retain severe disabilities.

Reframing the role of MCL1 in cancer signaling and metabolism

Rss Feed - Mon, 12/22/2025 - 21:50
A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology.

A senescence-based therapeutic approach for temporal lobe epilepsy

Rss Feed - Mon, 12/22/2025 - 20:55
Temporal lobe epilepsy, which results in recurring seizures and cognitive dysfunction, is associated with premature aging of brain cells.

Research highlights a potential therapeutic strategy for vascular dementia

Rss Feed - Mon, 12/22/2025 - 20:52
A possible new treatment for impaired brain blood flow and related dementias is on the horizon.

Altered stress signaling helps explain relapse in alcohol use disorder

Rss Feed - Mon, 12/22/2025 - 20:46
A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain-and offers insights on developing drugs to treat this condition.

Precision immunotherapy for TRBC2-positive T-cell malignancies

Rss Feed - Mon, 12/22/2025 - 20:34
Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive tumors.

Fatty diets reprogram hepatocytes and increase liver cancer risk

Rss Feed - Mon, 12/22/2025 - 20:20
One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.

Rethinking Mendelian assumptions in inherited retinal degenerations

Rss Feed - Mon, 12/22/2025 - 20:02
A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

Remodeling the tumor microenvironment to unlock CAR-T cell potential

Rss Feed - Mon, 12/22/2025 - 19:59
Chimeric antigen receptor T (CAR-T) cell therapy has revolutionized hematologic cancer treatment, but its efficacy in solid tumors remains limited by poor infiltration into the complex tumor microenvironment (TME).

Probiotic supplementation restores beneficial gut bacteria in breastfed infants

Rss Feed - Mon, 12/22/2025 - 19:54
In recent years, scientists have learned that key beneficial infant gut bacteria Bifidobacterium infantis are disappearing from infants in high-resource areas such as the United States and Europe.

Engineered extracellular vesicles enable antigen-specific regulatory T cell induction

Rss Feed - Mon, 12/22/2025 - 19:51
A research team at the Nano Life Science Institute (WPI-NanoLSI) and the Faculty of Medicine at Kanazawa University has developed a new class of engineered extracellular vesicles (EVs) capable of inducing antigen-specific regulatory T cells (Tregs), the immune cells that play a central role in suppressing excessive immune responses.

ARB drugs lead to better blood pressure treatment adherence

Rss Feed - Mon, 12/22/2025 - 12:51
Patients who start their blood pressure treatment with ARB drugs continue with the same medicine to a greater extent than patients who start out with other drugs.

Popular video games may offer meaningful emotional benefits for young adults

Rss Feed - Mon, 12/22/2025 - 12:24
A new study published by JMIR Serious Games reports that popular video games, such as the Super Mario Bros. and Yoshi games, may offer meaningful emotional benefits for young adults.

Women may derive greater long-term benefits from coronary artery bypass grafting compared with stents

Rss Feed - Mon, 12/22/2025 - 12:17
Women with severe coronary heart disease causing narrowing or blockages in the arteries may derive greater long-term benefits from coronary artery bypass grafting compared with percutaneous coronary intervention, also known as stenting, according to a large study by Weill Cornell Medicine investigators.

Homer1 gene plays a critical role in shaping attention

Rss Feed - Mon, 12/22/2025 - 11:57
Attention disorders such as ADHD involve a breakdown in our ability to separate signal from noise. The brain is constantly bombarded with information, and focus depends on its ability to filter out distractions and detect what matters.

Community awareness campaign helps improve early diagnosis of colorectal cancer in low-resource regions

Rss Feed - Mon, 12/22/2025 - 11:15
In low-resource regions such as Nigeria, most people with colorectal cancer are diagnosed too late for curative treatment options.

Splicing regulator U2AF1 promotes angiogenesis in cardiac injury

Rss Feed - Mon, 12/22/2025 - 11:04
A study published in Engineering shows that a protein called U2 small nuclear RNA auxiliary factor 1 (U2AF1), released by immune cells known as macrophages, helps grow new blood vessels in the heart after a myocardial infarction (MI) by altering how the gene Yap1 is spliced.

Study charts the escalating spread of resistant bacteria and fungi

Rss Feed - Mon, 12/22/2025 - 08:31
The success of modern medicine rests on the ability to control infections. But decades of antibiotic overuse—in hospitals, communities, and farms—have fueled a global surge in resistant microbes.

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