Feed aggregator

A new randomized clinical trial finds that simple reminder emails substantially increase clinicians' use of a database that supports safe prescribing of opioids and other drugs, even though opioid prescribing patterns themselves did not meaningfully change during the study period.

Increasing evidence suggests that the severe gum disease, periodontitis, may contribute to central nervous system disorders through chronic inflammation.

Knowledge graphs are a powerful tool for bringing together information from biological databases and linking what is already known about genes, diseases, treatments, molecular pathways and symptoms in a structured network.

Despite major therapeutic advances, breast cancer remains prone to recurrence, particularly in patients with early-stage disease who appear disease-free after treatment.

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

Children with peanut allergies may not need large doses of peanut oral immunotherapy (OIT) to build protection to peanut, finds a new study led by The Hospital for Sick Children (SickKids) and Montreal Children's Hospital. Researchers found that a small dose can help children with their peanut allergy and reduce the risk of severe reactions from accidental exposures, with less side effects than the current standard treatment.

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only five percent. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy.

A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.

Following stroke, some people experience a language disorder that hinders their ability to process speech sounds.

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's Association. The O'Banion Lab at the Del Monte Institute for Neuroscience at the University of Rochester has long been studying this disease and is looking more closely at the differences between male and female brains.

For the first time, clinicians have access to a clear, evidence-based roadmap for adjusting antiseizure medication doses during pregnancy and after childbirth.

New research from Fujita Health University reveals that talking can subtly delay the eyes’ ability to detect and stabilize on visual information.

Calcium (Ca2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, is widely unknown.

A new study published today in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast cancer.

The secret to a healthier and "younger" heart lies in the vagus nerve. A recent study coordinated by the Sant'Anna School of Advanced Studies in Pisa and published in Science Translational Medicine has shown that preserving bilateral cardiac vagal innervation is an anti-aging factor.

Prescription stimulants, such as Ritalin and Adderall, are widely used to treat attention deficit hyperactivity disorder (ADHD), including in children.

Encouraging people to get vaccinated is often seen as a public health success story. However, understanding how persuading people to roll up their sleeves to receive vaccines creates social division is crucial.

A newly developed artificial intelligence (AI) model is highly accurate in predicting blood loss in patients undergoing high-volume liposuction, reports a study in the January issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.