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Researchers developed FEDE, a high-fidelity digital brain twin pipeline that combines MRI-derived anatomy with biophysical modeling to reconstruct brain structure and simulate EEG activity. In a single toddler with autism spectrum disorder, the model closely reproduced recorded brain activity and suggested possible patient-specific alterations in neural noise and excitatory-inhibitory balance.

A Harvard Chan/de Beaumont national poll of 2,205 U.S. adults found CDC trust dropped to 50% one year into new federal public health leadership, while state and local health agencies remained more trusted.

A Nature Metabolism study identifies brain hyperglycosylation as a metabolic driver of Alzheimer’s disease, with increased N-glycan biosynthesis seen in human AD tissue and mouse models. Reducing glycosylation improved memory in AD mice, while glucosamine worsened memory deficits in 5xFAD mice and was associated with poorer outcomes in dementia patients.

A 14-day open-label pilot study in 63 healthy adults found that short-chain oat fiber was well tolerated at doses up to 20 g/day and was associated with improved gastrointestinal symptom scores.

Women on menopausal hormonal therapy face a decreased risk of low bone mineral density compared to those not using it, according to a study being presented Sunday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

People prescribed GLP-1 medications are more likely to start-and-stop than most people assume, according to a study being presented Sunday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

The first real-world study of the FDA-approved non-hormone treatment fezolinetant found the menopausal medication improved hot flashes, depression and anxiety in women, according to industry-sponsored research being presented Sunday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Oral corticosteroids (OCSs) are widely used and effective in the treatment of chronic inflammatory conditions such as arthritis, asthma, and autoimmune diseases. They work by reducing inflammation, relieving pain, and calming the immune system.

Male rats that were exposed to the widely used plasticizer di-(2-ethylhexyl) phthalate (DEHP) during early development exhibited increased anxiety behavior as adults, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Endocrine-disrupting chemicals (EDCs) that interfere with hormones were found in breast milk and in the urine of children from birth up to 6 months, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Longer lifetime exposure to female hormones may increase the risk of thyroid cancer in women, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

The incidence of type 1 diabetes among teens in Puerto Rico more than doubled from 2009 to 2021 and remained elevated through 2024, with an average annual increase of 4.1 percent, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Only a small number of men who were prescribed testosterone therapy received appropriate, guideline-concordant diagnostic testing, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill, by Sophia Sinha, M.D., clinical assistant professor at the University of Michigan in Ann Arbor, Mich.

Testosterone treatment may improve body composition, glucose metabolism and sexual desire in some older men at high risk of type 2 diabetes (T2D), but the benefits require engagement in a lifestyle program, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Eliminating sugar from your diet may be more detrimental than previously thought, according to an animal study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

People with an organ transplant who develop or have existing diabetes are more likely to die than those without diabetes, according to a comprehensive analysis of solid-organ transplant recipients, which is being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Northwestern Medicine scientists have identified a safety concern associated with GLP-1 drugs. Using health record data, the research team tracked more than 42,000 adults already taking at least two types of blood pressure medications.

Adults with obesity losing weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study being presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Some subgroups of children with precocious puberty-such as older girls with slowly progressing puberty-may not need the same level of testing or treatment, according to a new Endocrine Society Clinical Practice Guideline released today.

Women with HIV most often die from preventable, trauma-related conditions like substance use and mental illness - not the virus itself. Yet, these leading causes are largely missing from official death records, according to new research by UC San Francisco.