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As demand for heart transplants continues to far exceed the number of available donor hearts, experts at today's 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT) explored a critical question: how should this scarce, life-saving resource be allocated?

By studying and engineering heart tissue in the unique low-gravity environment of space, the laboratory of Arun Sharma, PhD, is uncovering new ways to protect and repair the failing heart.

A new study published in Engineering reveals that obakulactone (OL), a natural tetracyclic triterpenoid isolated from Phellodendri cortex, exerts a therapeutic effect on rheumatoid arthritis (RA) by promoting the degradation of acyl coenzyme A thioesterase 1 (ACOT1) via the ubiquitin‒proteasome pathway and restoring the homeostasis of unsaturated fatty acids.

A revelatory treatment for patients with life-threatening infectious diseases is being pioneered in Melbourne by researchers at The Alfred and Monash University.

A new study published in Engineering provides mechanistic insights into live-cell glycocalyx engineering and supports the rational design of next-generation adoptive cell therapies (ACTs) against B lymphoma, addressing limitations such as high costs and restricted antigen specificity in current treatments.

A study published in Engineering has identified fucosylated immunoglobulin G (IgG) as a key mediator contributing to adipose tissue dysfunction during aging, offering insights into age-related metabolic disorders and potential therapeutic targets.

Differences in brain connectivity are linked to several neurodevelopmental disorders, yet scientists still struggle to determine what changes are shared or unique to each condition.

Postmenopausal women are at higher risk for both osteoporosis and depression, yet no single treatment effectively addresses both conditions because their shared biological basis remains poorly understood.

Antibiotic resistance is making bacterial infections harder to treat, demanding new therapeutic strategies. A new review highlights bacterial extracellular vesicles (BEVs) as promising nanoscale tools that can kill pathogens, block infection, enhance vaccines, and deliver drugs.

A major study, led by researchers at Children's Hospital of Philadelphia, Nemours Children's Health, and Children's National Hospital and involving an extensive network of medical centers across the United States and abroad, found that different types of crystalloid fluid resuscitation were equally effective for staving off the most serious adverse kidney events after the treatment of pediatric patients with suspected septic shock.

At every age, children in the United States die at higher rates than peers in other high-income nations, according to a new study from Children's Hospital of Philadelphia.

New research from Monash University, the University of São Paulo and Deakin University shows a diet high in heavily processed foods can negatively impact the brain's ability to focus and increases the risk of developing dementia.

The heart's constant beating may actively suppress tumor growth in cardiac tissues, a new study reports. This is because cellular pathways in these tissues alter gene regulation in cancer cells to keep them from proliferating.

Scientists at UCLA have created one of the first cellular-resolution molecular maps detailing how Down syndrome alters human brain development before birth - a resource that resolves longstanding contradictions in the field and could lay the groundwork for future therapeutic strategies.

In a new research report, a team of scientists led by Johns Hopkins Medicine say people with severe obesity and a common type of heart failure experience weakened heart muscles, and that losing weight may reverse some of these effects.

Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they need to carry oxygen to tissues, even after shedding the vital structures they need to produce it.

The research group of Prof. Sanjiv Luther at the Department of Immunobiology of the University of Lausanne has discovered that a fibroblast subtype is essential for coordinating certain immune cells within lymph nodes.

If you think you need to 'go hard' at the gym to make your muscles stronger, think again!

A new research paper was published in Volume 18 of Aging-US on April 7, 2026, titled "Association of epigenetic age acceleration with MRI biomarkers of aging and Alzheimer's disease neurodegeneration."

International students face a range of health challenges in their daily lives due to language barriers, different cultural values, and unfamiliar healthcare systems.