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Exploring the link between underweight status and gut microbiota composition in Japanese women
Low body weight in young women has been linked to a range of health concerns, including disrupted menstrual cycles, infertility, weakened immune function, and a long-term decline in bone density.
Researchers visualize how brain network development is altered in rare childhood disorder
Researchers at the VIB-UAntwerp Center for Molecular Neurology have visualized how brain network development is altered in a model of KCNQ2-related developmental and epileptic encephalopathy, a rare childhood brain disorder.
Obesity treatment in the UK could become a "two-tier system", experts warn
Treatment for obesity in the UK could become a "two-tier system" where the most vulnerable patients miss out altogether.
Sensory effects of flavanols trigger physiological responses in the brain
Astringency is a dry, puckering, rough, or sandpapery sensation in the mouth caused by plant-derived polyphenols.
Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment
Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.
Studies identify complementary approaches to overcome drug resistance in KRAS G12C–mutant lung cancer
Two companion studies published in Cancer Research from scientists at Moffitt Cancer Center identify distinct but complementary approaches to overcoming drug resistance in KRAS G12C–mutant non-small cell lung cancer.
Evidence of previously unrecognized hub in the brain's lymphatic drainage system revealed
How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.
Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD
A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Proimmune Ltd introduces Prove® SL Self-Loading MHC Class I Monomers to improve T cell research flexibility
ProImmune Ltd, a global leader in life science reagents and services, today announced the launch of its new ProVE® SL Self-Loading MHC Class I Monomers.
Global study suggests potential for universal vaccine against Haemophilus influenzae
A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.
Massive cross-ancestry study explains why obesity risks differ around the world
A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.
COVID-19 in pregnancy may raise autism and neurodevelopmental disorder risk
Children born to mothers who contracted COVID-19 during pregnancy face a 29% higher likelihood of developmental disorders by age three, including speech, motor, and autism-spectrum delays. The risk was greatest for male offspring and infections occurring in the third trimester.
Common viruses sharply raise heart attack and stroke risk, major global review shows
In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.
Bowhead whale’s secret to long life revealed: precision DNA repair may hold clues for human aging
Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances genome stability even in human cells, revealing a potential pathway to strengthen DNA repair and slow aging.
Study confirms PSA screening improves survival and safety
After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.
Researchers uncover mechanism by which BRCA2-deficient tumors develop chemoresistance
One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.
Study uncovers neural mechanisms behind memory stabilization
Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers.
Study finds more commonalities between CTE and Alzheimer's disease at the genetic level
Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain.
First-of-its-kind resource created to identify people with genetic risk for elevated 'bad' cholesterol
An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated 'bad' cholesterol -- a major contributor to heart disease.
Oligodendrocyte progenitor cells promote blood vessel growth after stroke
Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.




