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Understanding why some people stay healthy without developing disease until late in life (have an increased healthspan), whereas others become infirm at a much younger age has important implications for the health of today's ageing population.

New research from large population studies provides invaluable evidence on genome screening of newborn babies to reduce risks from overdiagnosis.

In the largest genetic study of inflammatory bowel disease (IBD) traits to date, researchers have identified a genetic marker that is associated with more severe ulcerative colitis and Crohn's disease – the major forms of IBD.

A multicenter study of 1,333 active drivers with migraine found that 70.6% had experienced headache while driving, with headaches occurring during about 13% of driving sessions. The findings suggest that migraine-related symptoms may impair attention, increase sensitivity to road conditions, and contribute indirectly to driving cessation and accident risk.

Most pandemics start when a pathogen spreads from animals to humans. It's a leading explanation for the COVID-19 pandemic: the SARS-CoV-2 virus, which causes COVID-19, is a cousin to coronaviruses that live in bats.

A long-running Australian cohort study found that personality traits generally matured from early to middle adulthood, with agreeableness and conscientiousness rising and extraversion, openness, and neuroticism declining. People with persistent common mental disorders showed the clearest decline in neuroticism by midlife, but they still had higher emotional instability than peers without persistent mental health difficulties.

Problematic social media use was associated with more frequent self-reported everyday memory failures in 943 Spanish young adults aged 18 to 35. Everyday memory failures statistically accounted for much of the link between problematic social media use and both prospective and retrospective memory lapses.

A UK cost-of-illness projection estimates that direct NHS dental treatment costs for adult caries and periodontal disease will rise by 20%, from £4.42 billion in 2020 to £5.30 billion by 2050. The burden shifts strongly toward older adults and severe disease, supporting prevention and earlier intervention as NHS dental planning priorities.

Dr. Dan Landau, the Bibliowicz Family Professor of Medicine, and a member of the Sandra and Edward Meyer Cancer Center and the Englander Institute for Precision Medicine at Weill Cornell Medicine, has received a Lotus Award from the Pershing Square Foundation for research aimed at uncovering new immunotherapy targets in ovarian cancer.

GLP‑1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

A local research study led by scientists from the A*STAR Genome Institute of Singapore (A*STAR GIS) has uncovered how the gut microbiome can influence gene activity in the liver by acting on short stretches of regulatory DNA that function like molecular "switches".

In a new JNeurosci paper, Xuanyi Chen and Esti Blanco-Elorrieta, from New York University, explored whether Spanish–English speakers use the same or different brain mechanisms to speak each language.

Just 10 viral particles of the H5N1 bird flu that caused hundreds of influenza outbreaks in U.S. dairy cattle can cause infection in cows, a new study shows.

Researchers are warning that obesity is reshaping the global cardiovascular disease crisis, as trend data covering 204 countries reveal that heart disease now peaks in people aged 50-54 rather than the elderly and increasingly in South Asia, where rates have grown more than three times faster than global averages, according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

People with type 2 diabetes who nap longer than 30 minutes every day, regardless of their sleep patterns at night, increase their risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD), according to a study being presented Monday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

Problems in adulthood such as tobacco use disorder and some conditions related to the digestive system, heart, bladder, joints and brain, are all shown to be affected by some influences that occurred in childhood, according to research presented Saturday at ENDO 2026, the Endocrine Society's annual meeting in Chicago, Ill.

The growing number of people living with Parkinson's disease (PD), multiple sclerosis (MS) and motor neuron disease (MND) is being driven by different underlying factors, according to new research due to be presented at the European Academy of Neurology (EAN) Congress 2026 and published in Neurology.

A study conducted at the University of Oulu and Oulu University Hospital suggests that factors related to maternal weight are reflected in signaling particles produced by the maternal microbiota not only in the gut but also in amniotic fluid.

Prostate-targeted, engineered nanoparticles made of amorphous silica are effective in killing prostate tumors directly while enhancing anti-tumor immunity, according to a preclinical study led by investigators at Weill Cornell Medicine and the Cornell College of Engineering.

Scientists have long known that being obese increases the risk of dementia and Alzheimer's disease. What remains unclear is how that risk develops in the brain.