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Latest Medical Research News and Research
Updated: 38 min 31 sec ago

Disrupted brainstem-parahippocampal connectivity identified as a biomarker for delirium

Fri, 10/31/2025 - 23:04
Delirium, commonly observed in critically ill patients following intracerebral hemorrhage (ICH), is an acute neuropsychiatric disorder characterized by disturbances in attention, consciousness, and cognition.

Columbia researchers report first successful pregnancy using AI-guided sperm recovery method

Fri, 10/31/2025 - 22:51
Researchers at the Columbia University Fertility Center reported the first successful pregnancy using an AI-guided method they developed to recover sperm in men with azoospermia, in which ejaculate contains little or no sperm.

New $4.4 million grant funds first study of prefrontal cortical stimulation in severe bipolar disorder

Fri, 10/31/2025 - 22:45
A University of Minnesota Medical School research team, led by Ziad Nahas, MD, has been awarded a $4.4 million grant for a first-in-the-world study of prefrontal cortical stimulation in severe bipolar disorder.

Undergraduate researcher uncovers molecular secrets of HPV’s cancer-causing mechanisms

Fri, 10/31/2025 - 22:34
When Sean Fletcher walked into Sam Biswas' Medical and Molecular Sciences (MMSC) lab at the University of Delaware College of Health Sciences during the summer of his first year, he had no research or laboratory experience.

Molecular bumpers and glues rewire GPCR signaling for next-generation medicines

Fri, 10/31/2025 - 22:28
New research led by the University of Minnesota Medical School demonstrates that molecules acting as "molecular bumpers" and "molecular glues" can rewire G protein-coupled receptor (GPCR) signaling, turning the cell's busiest receptors into precision tools - opening the door to a new generation of safer, smarter medicines.

Dysfunction in chromosome-stabilizing protein identified as a cause of deadly illnesses

Fri, 10/31/2025 - 22:22
New research from the University of Wisconsin–Madison reveals that dysfunction in a protein essential to maintaining stability in our chromosomes may be responsible for serious - and sometimes deadly - diseases.

Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers

Fri, 10/31/2025 - 22:11
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and disease progression.

Sirolimus-eluting balloon emerges as a safe and effective option for coronary in-stent restenosis

Fri, 10/31/2025 - 21:51
A new drug-eluting balloon can perform just as well as the standard treatment for patients with coronary in-stent restenosis (ISR) undergoing repeated percutaneous coronary intervention (PCI).

Immune cell dysregulation and inflammatory mediators shape epilepsy risk

Fri, 10/31/2025 - 21:22
Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal mechanisms remain unclear.

Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation

Fri, 10/31/2025 - 14:43
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally occurring RNA molecule in the kidney activates a mutated immune receptor, triggering a chain reaction.

Study reveals how melanoma evolves to resist immunotherapy

Fri, 10/31/2025 - 14:18
A study led by UCLA Health Jonsson Comprehensive Cancer Center investigators reveals how melanoma, the deadliest form of skin cancer, evolves to resist immunotherapy and identifies a potential strategy to prevent or reverse that resistance.

Lab-grown organoid offers a platform to study how liver scarring develops

Fri, 10/31/2025 - 13:20
As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

Neuroscientists uncover a surprising role for "Frazzled" protein in the nervous system of fruit flies

Fri, 10/31/2025 - 12:58
Florida Atlantic University neuroscientists have uncovered a surprising role for a protein named "Frazzled" (known as DCC in mammals) in the nervous system of fruit flies, showing how it helps neurons connect and communicate with lightning speed.

Genetic insights into vestibular system damage from ototoxic drugs

Fri, 10/31/2025 - 12:50
The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, leading to alterations in balance and other motor skills.

New method enhances precision in bionic limb movement interpretation

Fri, 10/31/2025 - 12:36
Despite enormous progress in the past two decades, the intentional control of bionic prostheses remains a challenge and the subject of intensive research.

Study reports increase in leg and foot amputations in Illinois hospitals from 2016 to 2023

Fri, 10/31/2025 - 10:59
Rates of leg and foot amputations in Illinois hospitals increased 65% between 2016 and 2023, reports a new Northwestern Medicine study.

Breakthrough study maps impact of thousands of variants in heart disease gene

Fri, 10/31/2025 - 10:54
An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more than 17,000 variants in a major gene associated with the development of premature atherosclerotic heart disease.

Mathematical models explain food movement and churning in the digestive tract

Fri, 10/31/2025 - 10:44
Synchronization abounds in nature: from the flashing lights of fireflies to the movement of fish wriggling through the ocean, biological systems are often in rhythmic movement with each other.

How nerve cells in the gut adapt to microbial and immune challenges

Fri, 10/31/2025 - 10:31
​Ramnik Xavier, MD, PhD, of the Department of Molecular Biology at Massachusetts General Hospital, is the senior author of a paper published in Science, "Regional encoding of enteric nervous system responses to microbiota and type 2 inflammation."

Novel approaches to understanding EETs and cardiovascular disease

Fri, 10/31/2025 - 10:13
Some products of arachidonic acid have already been well studied: the prostanoids formed by cyclooxygenases are central mediators of inflammation, fever, and pain.

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