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This large prospective UK study compared five low-cost fingertip pulse oximeters with arterial blood gas measurements and found that readings varied systematically by skin tone and oxygen saturation level. Small average overestimations in darker skin translated into clinically meaningful increases in missed hypoxemia at commonly used SpO2 thresholds.

This large prospective study integrated blood metabolomics, genetics, and lifestyle data to identify hundreds of metabolites associated with long-term risk of type 2 diabetes in initially healthy adults. A validated 44-metabolite signature improved risk prediction beyond conventional factors, offering insights into biological pathways and opportunities for earlier, more precise prevention.

A statewide evaluation found that California schools receiving TUPE funding delivered more antitobacco education and activities and reported lower student tobacco use than non-funded schools. The association was driven mainly by reduced vaping, within a broader environment of strong statewide tobacco control.

Six weeks of Ashwagandha root extract supplementation in semi-professional team-sport athletes was associated with sex-specific effects during pre-season training. Females showed improved perceived recovery with stable cortisol, while males demonstrated gains in lower-body power with stable cortisone levels.

Glaciers harbor both ancient and human-derived antibiotic resistance genes, preserved in ice and increasingly mobilized by climate-driven melt. This global review proposes a glacier-to-downstream “continuum” to understand how resistance genes may move through connected freshwater ecosystems.

As another new year gets under way many of us will be looking for a way of boosting how we feel but is it better to hit the gym or mediate in nature? Now new research by Swansea experts has provided the largest ever comparison of wellbeing-focused interventions delivered to adults.

During World War II, Sweden was officially neutral, but life at home was anything but untouched by the conflict. A new study from Stockholm University shows that the war years fundamentally changed Swedish thoughts about sexual health, helping turn the condom from one protective option among many into the dominant safeguard against venereal disease.

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia and other respiratory infections-to obtain cholesterol and other essential lipids directly from the human body.

Women and people with anxiety are both prone to low confidence in their own abilities, but a new study by University College London (UCL) researchers has found that the two groups are prone to two distinct types of underconfidence.

Novel hybrid polymer nanocarriers enable effective vaccine delivery in the lungs and the targeted activation of immune cells.

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the first time, in a study led by investigators at Weill Cornell Medicine and the New York Genome Center.

University of Virginia School of Medicine researchers have revealed how the popular, low-carb ketogenic diet protects against epilepsy seizures and possibly neurodegenerative diseases such as Alzheimer's and Parkinson's.

High blood pressure becomes more common after age 40years yet new research from The Irish Longitudinal Study on Ageing (TILDA) at Trinity College Dublin shows that many people in Ireland with hypertension are still not optimally diagnosed or treated based on European Gudelines.

When agitated dementia patients wander or shout through the night, families and caregivers understandably feel the need to treat this frightening and potentially dangerous behavior. Antipsychotic medications are often resorted to with such patients, contributing to increases in antipsychotic treatment rates among older people.

To gain more knowledge about how ultra-processed food affects us, we need new research methods, claim researchers. Now they are looking to better understand our intestinal flora.

An international team of scientists, led by Nanyang Technological University, Singapore (NTU Singapore), has discovered a new way that could speed up the healing of chronic wounds infected by antibiotic-resistant bacteria.

In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.

The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous cells in individuals with Lynch Syndrome (LS), according to a study from researchers at The University of Texas MD Anderson Cancer Center.

Taking paracetamol during pregnancy does not increase the risk of autism, attention-deficit hyperactivity disorder (ADHD), or intellectual disability among children.

Sleep problems are increasingly common among children and adolescents, affecting emotional regulation, cognitive development, and healthy conditions.