Rss Feed
Genetic bottlenecks limit the rise of pandemic cholera strains
A new study by the Genomics and Microbial Evolution Group at the Miguel Hernández University of Elche (UMH) together with the Department of Host-Microbe Interactions at St. Jude Children's Research Hospital in Memphis, USA, sheds light on one of the great enigmas of microbiology: why only certain strains of common bacteria become pandemic pathogens.
Gut microbiota and metabolic changes linked to pregnancy risks in women with PCOS
A new study presented today at the 41st Annual Meeting of the European Society of Human Reproduction and Embryology (ESHRE) reveals that women with polycystic ovary syndrome (PCOS) have distinct gut microbiota and metabolic signatures linked to premature endometrial aging and a higher risk of adverse pregnancy outcomes.
FAU researchers secure key grants to target new gene in the fight against glioblastoma
Florida Atlantic University researchers have secured two key grants to investigate targeting a gene for the first time as a new approach to treat glioblastoma, a very aggressive and fast-growing type of brain cancer.
GATE complex discovery sheds light on CMV's evasion of immune defenses
New research from the University of Pittsburgh School of Medicine and La Jolla Institute for Immunology, published today in Nature Microbiology, reveals an opportunity for developing a therapy against cytomegalovirus (CMV), the leading infectious cause of birth defects in the United States.
Economic downturns increase childhood malnutrition risks
Even small drops in national income can significantly increase the risk of various forms of childhood malnutrition- not only undernutrition but also overweight and obesity, shows a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.
Ancient DNA sheds light on the origins of leprosy in the Americas
Hansen's Disease, more commonly known as leprosy, is a chronic disease that can lead to physical impairment. Today it exists in over 100 countries, and while the infection is treatable, access to treatment varies widely with socioeconomic conditions.
Long periods of parental leave after childbirth associated with higher risk of unhealthy behavior
A new study by the University of Vienna shows that particularly long periods of parental leave around the birth of a child are associated with a higher risk of unhealthy behavior - specifically smoking - in the long term.
Study provides insights into the immune response following pig-to-human kidney xenotransplants
A pioneering study has provided unprecedented insights into the immune response following pig-to-human kidney xenotransplantation.
New trial offers hope for effective treatment of spinal cord injuries
Spinal cord injuries are currently incurable with devastating effects on people's lives, but now a trial at Waipapa Taumata Rau, University of Auckland offers hope for an effective treatment.
New AI tool helps clinicians identify brain activity patterns linked to nine types of dementia
Mayo Clinic researchers have developed a new artificial intelligence (AI) tool that helps clinicians identify brain activity patterns linked to nine types of dementia, including Alzheimer's disease, using a single, widely available scan - a transformative advance in early, accurate diagnosis.
N2 deep sleep powers your next aha moment, study reveals
A new study in PLOS Biology shows that deep N2 sleep, rather than light N1 sleep, dramatically boosts the likelihood of “aha” moments in a challenging perceptual task. The researchers also reveal that aperiodic brain activity during sleep best predicts who will gain insight after a nap.
Comprehensive study maps genetic mutations in SLC13A5 linked to epilepsy
Citrate is essential for the metabolism and development of neurons. A membrane transport protein called SLC13A5 plays a central role in this process and has previously been linked to a particularly severe form of epileptic encephalopathy.
Vegetables and dairy may lower endometriosis risk
A major umbrella review shows that higher intake of vegetables and dairy products is linked to a lower risk of endometriosis, while butter and high caffeine intake appear to increase risk. However, the evidence remains weak due to limitations in existing observational studies.
VIRMA protein regulates brain development by controlling ribosome biogenesis
Ribosomes are tiny molecular machines inside all living cells that build proteins, and ribosome biogenesis is the complex, multi-step process by which they are made.
Gene therapy shows promise for reducing stroke risk in patients with sickle cell disease
Gene therapy for sickle cell disease may help improve a major contributing factor to stroke risk in patients, reports a new study from St. Jude Children's Research Hospital.
Ionophore use in farming drives global spread of antibiotic resistance genes, study finds
Researchers identified the widespread presence of the ionophore resistance genes narA and narB in over 2,400 bacterial isolates across 51 countries. These genes are often genetically linked to resistance against critically important human antibiotics, raising concerns over agricultural practices and global antimicrobial resistance.
Coffee’s hidden compounds could help fight type 2 diabetes
A comprehensive review of nearly 150 studies reveals that coffee polyphenols may help regulate blood sugar and reduce inflammation linked to type 2 diabetes. However, most evidence comes from preclinical research, and robust clinical trials are needed to confirm benefits.
Just 150 minutes of exercise a week could reverse prediabetes
Engaging in more than 150 minutes of physical activity per week quadrupled the odds of reversing prediabetes to normal glucose levels in Colombian adults. Higher BMI and HbA1c remained strong barriers to reversal, highlighting the power of lifestyle interventions.
Are sweeteners really making our children’s diets healthier?
Higher consumption of low-calorie sweetened (LCS) products among UK children was not consistently linked to reduced free sugar intake, and may reflect less healthy overall dietary patterns. Over 11 years, improvements in dietary quality were slowest among those consuming the most LCS products.
How 50,000 years of ancestry shaped India’s unique disease patterns
Scientists sequenced the genomes of 2,762 individuals across India, revealing the country’s unique ancestral makeup and a wealth of previously undocumented disease-related gene variants. The study highlights how ancient migrations, founder effects, and endogamy have shaped both diversity and disease risk in India.