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Weekly THC levels reveal when cannabis use becomes a disorder
Weekly cannabis use accurately predicts the risk of developing cannabis use disorder.
Study highlights potential of ferroptosis-based approaches to treat cancer
Therapies that target the utilization of fat by tumors and activate a type of cell death dependent on fat molecules may be a promising avenue to treat cancer, according to new research by UTHealth Houston.
Immune dysfunction persists after combined TB and HIV therapy
The immune system remains seriously out-of-whack – in an inflammatory state of overactivation and impaired functionality – following the international gold standard for treating people with latent tuberculosis (TB) and HIV, a team at Texas Biomedical Research Institute reports in Nature Communications.
Scientists reveal how cholera bacteria activate toxin genes in the human gut
Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of deaths reported worldwide each year.
Six week casting proves as effective as surgery for unstable ankle fractures
Wearing a cast for six weeks appears to be no less effective than surgery for healing unstable ankle fractures and carries fewer treatment related harms, finds a clinical trial from Finland published by The BMJ today.
Gut bacteria compound during pregnancy protects offspring from fatty liver disease
Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.
Bacterial metabolite enhances immune checkpoint therapy against lung cancer
UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response to lung cancer immunotherapy treatment in mice and can now be made into a drug for testing in humans.
Scientists uncover promising therapeutic target for autoimmune disease affecting the brain
Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain.
Pregnant individuals with inflammatory bowel disease show heightened vaginal inflammation
Pregnant individuals with inflammatory bowel disease (IBD) have higher levels of pro-inflammatory immune molecules, known as cytokines, in their vaginal mucosa than their healthy counterparts, according to a new study published January 14, 2026 in the open-access journal PLOS One by Ana Maldonado-Contreras of University of Massachusetts Chan Medical School, U.S., and colleagues.
Study reveals genetic signatures linked to HIV-related cognitive impairment
Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled.
Rare immune events link Epstein Barr virus to early multiple sclerosis damage
Autoimmune diseases such as multiple sclerosis arise when the immune system turns against the body itself.
Bradycardia emerges as key clinical sign of xylazine-opioid overdose
Researchers have identified bradycardia-an abnormally low heart rate–as a symptom of xylazine-opioid overdose.
Age-tailored therapies needed for treating the young and old with sepsis
Dealing with an infection isn't as straightforward as simply killing the pathogen. The body also needs to carefully steer and monitor its immune response to prevent collateral damage.
Heart failure care gaps found among Asian American ethnic groups
Using nearly a decade of data (2015–2023) from 800+ U.S. hospitals and more than 700,000 patients overall, Northwestern researchers found that when Asian American heart failure patients are separated by ethnicity, rather than grouped together as "Asian," important differences in care emerge across groups including Filipino, Vietnamese, Chinese, Asian Indian, Korean and Japanese patients.
HIF1 protein identified as key driver of tendon pain
Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems.
Post-meal blood sugar spikes linked to increased Alzheimer's risk
A new study led by researchers from the University of Liverpool has found that spikes in blood sugar after meals may increase the risk of Alzheimer's disease.
Disease-responsive nanoparticles enable ghrelin mRNA therapy in osteoarthritis
Nitin Joshi, PhD, and Jingjing Gao, PhD, of the Department of Anesthesiology at Mass General Brigham, are the co-senior authors of a paper published in Nature Nanotechnology, "A disease-severity-responsive nanoparticle enables potent ghrelin mRNA therapy in osteoarthritis." Mahima Dewani, PhD, is the lead author of this study.
WSU study reveals gaps in end-of-life care education for doctors
Doctors encounter death and dying significantly more than most people. It's the price of saving lives and helping people.
RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model
Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.
Bacterial toxin shrinks tumors, enhances immune response in colorectal cancer study
A toxin secreted by cholera bacteria can inhibit the growth of colorectal cancer without causing any measurable damage to the body. This is shown by a new study by researchers at Umeå University, Sweden.




