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How does the brain take out its trash? That is the job of the brain's lymphatic drainage system, and efforts to understand how it works have pushed the boundaries of brain-imaging technologies.

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

ProImmune Ltd, a global leader in life science reagents and services, today announced the launch of its new ProVE® SL Self-Loading MHC Class I Monomers.

A vaccine that tackles the bacteria that cause up to 200 million childhood infections every year could be possible, experts say.

A massive cross-ancestry genetic study involving over 839,000 adults identified 13 genes linked to obesity, including five never before associated with the condition. The findings highlight how global genetic diversity can uncover new biological pathways and potential treatment targets for obesity.

Children born to mothers who contracted COVID-19 during pregnancy face a 29% higher likelihood of developmental disorders by age three, including speech, motor, and autism-spectrum delays. The risk was greatest for male offspring and infections occurring in the third trimester.

In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.

Researchers discovered that bowhead whales achieve extraordinary longevity and cancer resistance through highly efficient and precise DNA repair mechanisms. A whale-specific protein, CIRBP, enhances genome stability even in human cells, revealing a potential pathway to strengthen DNA repair and slow aging.

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

One of the biggest challenges in cancer treatment is chemoresistance: tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers.

Chronic traumatic encephalopathy (CTE) – most often found in athletes playing contact sports – is known to share similarities with Alzheimer's disease (AD), namely the buildup of a protein called tau in the brain.

An international team led by a University of Pittsburgh School of Medicine scientist has created a first-of-its-kind resource to identify those with a genetic risk for elevated 'bad' cholesterol -- a major contributor to heart disease.

Stroke is a leading cause of death and disability, affecting 1 in 4 people during their lifetime. Stroke happens when blood vessels in the brain get clogged or damaged, impairing blood flow and oxygen supply to the brain, which leads to death of neurons and other brain cells.

If cancer is a disease of overabundance, where cells divide without restraint and tumors grow despite the body's best interests, then degenerative diseases are disorders of deprivation.

Using targeted radiation during surgery - referred to as intraoperative radiation - to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce the recurrence rate around the pancreas to 5%.

Just a few fibers are enough for the two hemispheres of the brain to communicate with each other. This was shown by a new international study led by Professor Dr Michael Miller (University of California, Santa Barbara) and Professor Dr Lukas J. Volz (Department of Neurology at University Hospital Cologne and the University of Cologne's Faculty of Medicine) in close collaboration with Professor Dr Christian Bien's team at the Bethel Epilepsy Centre (University Hospital OWL at Bielefeld University).

A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels in diabetic patients and increasing exercise capacity for better health outcomes.

A new case report was published in Volume 12 of Oncoscience on October 9, 2025, titled "Vulvar mucinous cyst mimicking common lesions with concurrent multiple bartholin cysts in a reproductive-age woman: A rare case report and review of literature."

Could slightly elevated blood sugar levels lead to serious health problems in the future? A single patient's question sparked nearly a decade of research leading to the development of a landmark model that could shape how clinicians and researchers understand and manage diabetes across the US.