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Review maps Toxoplasma hotspots: Half in Eastern Europe infected by age 44
Researchers systematically reviewed and modeled Toxoplasma gondii seroprevalence across 25 European countries. The study found striking regional differences, with highest infection levels in eastern and western Europe and lowest in the UK and northern regions.
Can honey protect your brain? Study reviews its potential against Alzheimer's
This review examined 27 preclinical studies on honey and Alzheimer’s disease, showing honey’s bioactive compounds counter oxidative stress, inflammation, and amyloid buildup. Despite promising lab results, no human trials exist, underscoring the need for clinical research.
Why metformin could protect the brain by rewiring mitochondria
Metformin boosts human oligodendrocyte differentiation and myelination across stem-cell, organoid, and chimera models. The study links these effects to mitochondrial metabolic shifts, supporting its potential as a therapy for multiple sclerosis.
Breastfeeding at six months boosts children’s IQ and academic skills into adolescence
Breastfeeding at six months was linked to higher IQ, better reading and math skills, and improved conversational abilities in children, according to the ALSPAC study. The findings, based on 42 significant outcomes, highlight long-term cognitive advantages but stop short of proving causality.
How a Mediterranean diet helps women manage menopausal symptoms
A cross-sectional study of 149 postmenopausal women found that greater adherence to a modified Mediterranean diet was linked to lower odds of moderate to severe hot flashes and sexual symptoms. While psychological and physical domains showed no significant association, the results support further evaluation of diet as a non-hormonal strategy for menopausal care.
Cancer-related nerve injury triggers inflammation and immunotherapy resistance
Cancer cells can break down the protective covers around nerves, causing nerve injury that triggers chronic inflammation leading to immune exhaustion and eventual resistance to immunotherapy, according to new research from The University of Texas MD Anderson Cancer Center.
Genomic clues uncover early origins of multiple myeloma
A new study maps out the timeline of DNA damage for multiple myeloma, the second most common blood cancer.
Gait retraining reduces pain and slows knee damage in osteoarthritis
Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.
Study provides evidence for a causal genetic link between prostate cancer and urothelial carcinoma
Prostate cancer is among the most common cancers in men and a leading cause of cancer-related deaths. With improved detection and therapies, survival rates have risen, but this progress comes with a new concern: the risk of secondary primary malignancies.
New hypothesis links internal fat biology to heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person's internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart.
Drug-coated devices not associated with improved outcomes in patients with peripheral artery disease
Drug-coated stents and balloons were not associated with reduced risk of amputation or improved quality of life compared with uncoated devices in two trials in peripheral artery disease (PAD), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.
Tailored risk-based treatment does not improve outcomes in atrial fibrillation
An individually tailored multidimensional risk-based treatment strategy was not associated with improvements in clinical outcomes compared with usual guideline-based care in patients with atrial fibrillation (AF), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.
Research finds no added benefit from routine CT imaging after left main coronary intervention
Routine coronary computed tomography (CCT)-based follow-up after percutaneous coronary intervention (PCI) of the left main coronary artery did not reduce death, myocardial infarction (MI), unstable angina or stent thrombosis compared with symptom-based follow-up, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.
ICD treatment does not lower death risk in patients with abnormal ECG after myocardial infarction
Prophylactic implantable cardioverter defibrillator therapy did not reduce mortality in patients with a prior myocardial infarction, persistent moderate left ventricular systolic dysfunction and abnormal ECG markers, according to late-breaking research presented in a Hot Line session today at ESC Congress 2025.
AMALFI trial finds small increase in AF diagnosis with mail-based ECG patch monitoring
A mail-based atrial fibrillation (AF) screening programme with ECG-patch monitoring led to a modest long-term increase in AF diagnosis and anticoagulation exposure in older patients at moderate-to-high stroke risk, according to a late-breaking trial presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in JAMA (The Journal of the American Medical Association).
Diabetes drug metformin alters blood metal levels in humans
The widely used diabetes drug metformin changes blood metal levels in humans. The Kobe University study is an important step in understanding the drug's many actions and designing better ones in the future.
Scientists discover molecular brake that limits T cell attack on tumors
In a discovery that could expand the array of current cancer immunotherapy treatments, scientists at Harvard Medical School have identified a new molecular brake that hinders the ability of T cells to attack tumors.
Better education and income reduce anxiety about growing old
Investigating aging anxiety in China, this research links socioeconomic status to mental health, showing how education and income can alleviate fears of aging.
Can oral bacteria make heart disease worse?
The presence of viridans streptococci in coronary plaques indicates a role in atherosclerosis, potentially influencing heart disease outcomes.
Babies fed blueberries show fewer allergy symptoms and boosted immune balance
Daily blueberry powder given to infants during complementary feeding modestly influenced allergic symptom resolution and shaped immune biomarker–microbiota associations. Findings suggest early diet may play a role in immune development, though results are preliminary and exploratory.