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Preliminary study shows intraoperative radiation's success against pancreatic cancer spread
Using targeted radiation during surgery - referred to as intraoperative radiation - to eliminate pancreatic cancer cells that have spread to areas around the pancreas, investigators at Johns Hopkins have been able to reduce the recurrence rate around the pancreas to 5%.
How branding and peer pressure keep kids hooked on energy drinks
Children and adolescents in North East England still find energy drinks easy to access despite a voluntary UK ban, drawn by taste, price, and powerful marketing. Hydration drinks like PRIME are viewed as “healthier,” even though young consumers often misunderstand their ingredients and health impacts.
Plant-based diets could curb climate change and infectious diseases, experts say
A new review in Open Forum Infectious Diseases links animal agriculture to climate change, antimicrobial resistance, and infectious disease spread. The authors urge healthcare providers to promote plant-based diets as a practical step to protect planetary and public health.
Women gain stronger heart protection from exercise than men, study reveals
Researchers analyzing over 85,000 UK Biobank participants found that women gain greater cardiovascular benefits from physical activity than men, needing only half the exercise to achieve similar reductions in coronary heart disease and mortality risk. The study underscores the importance of sex-specific guidelines for CHD prevention.
AI-powered LifeClock forecasts diseases years before symptoms appear
Researchers have developed LifeClock, an AI-driven biological clock trained on over 24 million electronic health records to estimate biological age across the human lifespan. The model accurately predicts disease risk years in advance, revealing distinct developmental and aging processes.
Wireless retinal implant restores sight in patients blinded by advanced macular degeneration
A new trial shows that a wireless subretinal implant, the PRIMA system, restored central vision in patients with geographic atrophy caused by age-related macular degeneration. After one year, 81% achieved clinically meaningful vision gains and most could read at home using prosthetic vision.
Exploring the gut-brain-immune axis in neurodegeneration
Neurodegenerative diseases (NDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), represent a growing global health burden, particularly in aging populations.
Uncovering mechanisms of neuronal migration in the adult brain
Researchers have discovered how newly created neurons depend on blood flow in the adult brain to travel from their site of origin to their final location.
Clinical Frailty Scale can quickly predict mortality in patients with heart failure
Frailty is closely linked to adverse outcomes in older adults, particularly those with heart failure. Numerous epidemiologic studies show that frailty has important prognostic value in this population, underscoring the need for routine assessment.
Study highlights non-inferiority of super-high-pressure non-compliant balloons in coronary interventions
New study findings show that utilizing super-high-pressure non-compliant balloons (NCB) is non-inferior to intravascular lithotripsy (IVL) balloon catheters for lesion preparation and stent expansion in severely calcified lesions during percutaneous coronary intervention (PCI).
Landmark trial shows drug-eluting balloon as effective option for in-stent restenosis
Results from the first randomized clinical trial in the United States to compare a sirolimus-eluting balloon (DEB) to control group consisting of drug-eluting stent (DES) and balloon angioplasty (BA) for the treatment of bare-metal and DES in-stent restenosis (ISR) deemed DEB to be noninferior to conventional therapies.
Cutting balloon angioplasty proves noninferior to intravascular lithotripsy in treating calcified coronary lesions
Results from the first randomized controlled trial to directly compare the safety and efficacy of cutting balloon (CB) angioplasty to intravascular lithotripsy (IVL) prior to drug-eluting stent (DES) implantation for the treatment of calcified coronary artery disease found CB to be noninferior to IVL.
Lessons from COVID-19 could help communities better prepare for the next pandemic
The COVID-19 pandemic has provided researchers with a wealth of information on contemporary successes and failures in combating an emerging pathogen.
Mount Sinai receives $4.5 million grant to investigate neural mechanisms underlying bipolar disorder
The Icahn School of Medicine at Mount Sinai is pleased to announce it has received a three-year, $4.5 million grant from BD2: Breakthrough Discoveries for thriving with Bipolar Disorder to investigate the neural mechanisms underlying bipolar disorder and pioneer novel neuromodulation-based treatment strategies.
Newly discovered perineural pathway enables HIV virus to redistribute throughout the body
Addressing the question of whether and how immune cells (macrophages) in the central nervous system (CNS) traffic out, researchers have now identified a perineural pathway through which the HIV virus can redistribute throughout the body.
BU researcher secures grant to investigate the link between nursing home architecture and health outcomes
Diana Anderson, MD, M.Arch, assistant professor of neurology at Boston University Chobanian & Avedisian School of Medicine, has received a $270,418 grant from the Patrick and Catherine Weldon Donaghue Medical Research Foundation for her project "Investigating the Relationship between Nursing Home Architecture and Health Outcomes."
Precursor of dopamine increases willingness to wait for larger delayed rewards
A research team from the University of Cologne conducted one of the most comprehensive studies on dopamine and decision-making in humans so far, providing evidence for effects of the former on the latter.
Reducing prescriptions of sleep drugs in older adults could provide health and economic benefits
Millions of older Americans suffering from insomnia regularly use prescription sleep medications, despite the risk of serious side effects-such as falls, broken bones
Study finds clear link between osteomalacia and increased risk of complicated deliveries
A research team at Uppsala University has identified a clear link between osteomalacia – a form of bone softening commonly caused by vitamin D deficiency – and a fivefold increased risk of emergency cesarean sections or the need for vacuum-assisted delivery.
Circadian rhythm disruptions may increase the risk of cardiovascular disease
As modern lifestyles increasingly challenge the body's natural circadian rhythm, the American Heart Association is spotlighting the potential health consequences of regular disruptions to our body's internal clock with a new scientific statement published today in its flagship journal Circulation.




