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Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV
A new UCLA study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development.
Subtle brain changes in football players could predict the risk of chronic traumatic encephalopathy
Brain scans from American football players reveal subtle differences in the brain's outer grooves when compared to scans from otherwise healthy men who never played contact or collision sports, a new study shows.
Hypoxia weakens the body's infection defense by changing genetic material of neutrophils
Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body's ability to fight infection, new research shows.
Reducing femoral fractures in total hip replacement with safer implant designs
As populations continue to age, total hip replacement (THR) is becoming an increasingly common surgical procedure.
COVID-19 pandemic linked to diminishing public trust in childhood vaccines
An international study led by the Azrieli Faculty of Medicine in the Galilee at Bar-Ilan University reveals that the COVID-19 pandemic has contributed to a diminishing public trust in childhood vaccines, resulting in declining vaccination rates and a resurgence of preventable, life-threatening diseases such as measles.
Opt-out organ donation policies may reduce living organ donations
Every day, 17 Americans die while waiting for an organ transplant. Opt-out organ donation policies, which enroll everyone into post-mortem donation programs by default unless people choose to opt out, have been touted as a way to increase the supply of desperately needed organs.
Researchers discover a previously unknown genetic cause for microcephaly
Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay.
Liver cirrhosis found to be more common in low-income households
Liver cirrhosis is significantly more common in low-income households than in high-income households. This is the result of a national study which, according to the researchers, calls for more preventive action in the most vulnerable groups.
Electronic health record data reveals trends in cardiovascular diseases before and after COVID-19
The electronic health record data analyzed in this study is anonymized and never leaves a secure data environment, which is only accessible by approved researchers working on approved projects.
Scripps Research wins $4 million CIRM grant to develop novel platform for neurodevelopmental disorders
Most people are born with two functioning copies of each gene-one inherited from each parent. In many cases, having just one working copy is enough for the body to function normally.
New software enables real-time pathogen surveillance in the air and environment
Metagenomics is the study of all organisms present in a particular environment, such as soil, water, or the human body. A key part of metagenomic analysis is understanding what species are present (classification), how much of each there is (abundance), and the function of the microorganisms present.
New research highlights crucial role of continuous walking patterns for cardiovascular benefit
An international study led by experts at the University of Sydney and the Universidad Europea in Spain has found that longer periods of continuous walking are more beneficial to cardiovascular health than walking the same number of steps in shorter, more sporadic bouts.
Air pollution, even below EPA guidelines, increases breast cancer risk
Women living in parts of the United States with lower air quality, especially neighborhoods with heavy emissions from motor vehicles, are more likely to develop breast cancer, according to a multiyear analysis involving more than 400,000 women and 28,000 breast cancer cases.
Clinically significant valvular heart disease vastly underdiagnosed in U.S. elders
Results from the PREVUE-VALVE study suggest that there are currently at least 4.7 million people aged 65-85 living with moderate or greater valvular heart disease (VHD) in the United States, and at least 10.6 million with clinically significant VHD, most of whom are unaware of their condition.
Novel antibiotic shows activity against WHO high priority pathogen VRE
Chemists from the University of Warwick and Monash University have discovered a promising new antibiotic that shows activity against drug-resistant bacterial pathogens, including MRSA and VRE.
Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding
Maternal peanut and peanut butter consumption during pregnancy and breastfeeding shaped DNA methylation patterns in children, particularly in genes regulating neurodevelopment and inflammation. These findings suggest maternal diet can prime offspring epigenetic sensitivity to breastfeeding duration.
Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease
Study reveals that group B [FeFe]-hydrogenase is the primary enzyme driving fermentative hydrogen production in the healthy human gut, mainly through Bacteroides species. These genes are significantly depleted in Crohn’s disease, indicating a metabolic shift and altered hydrogen cycling dominated by respiratory bacteria
Obesity’s health risks shift with age and sex, new genetic study reveals
Using a new time-resolved Mendelian randomization approach in over 360,000 UK Biobank participants, Karlsson et al. revealed that the causal impact of obesity changes across life, with distinct age- and sex-specific risk patterns for diabetes, heart disease, atrial fibrillation, and osteoarthritis.
Can cheese help prevent dementia? Japanese researchers say it might
Older Japanese adults who ate cheese at least once a week had a 21–24% lower risk of developing dementia over three years. The association remained significant even after adjusting for lifestyle and socioeconomic factors, suggesting a modest but meaningful protective effect.
Sirolimus-eluting balloon strategy matches drug-eluting stents in large international PCI trial
New study results from a large international all-comer population of percutaneous coronary intervention (PCI) candidates found that utilizing a strategy of sirolimus-eluting balloons with bailout stenting only if necessary was noninferior to routine drug-eluting stent (DES) implantation as part of the treatment for de novo coronary artery disease.




