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Engineering digital twins to transform diagnosis and treatment for GI disorders
For many people, gastrointestinal (GI) disorders are chronic and life-altering conditions. Yet despite their prevalence, doctors are often challenged by patients experiencing persistent symptoms with no way to accurately identify and diagnose diseases.
Study identifies key metric for safe blood brain barrier opening in glioblastoma patients
Researchers found that acoustic emission dose-an acoustic signal from microbubbles-could predict how to adjust ultrasound power and open the blood brain barrier for delivering drugs in patients with glioblastoma.
History of traumatic brain injury tied to greater chance of malignant brain tumors
New research led by investigators at Mass General Brigham suggests a link between a history of traumatic brain injury (TBI) and risk of developing a malignant brain tumor.
New study reveals long road to seizure control for people with focal epilepsy
Antiseizure medications help the majority of people with focal epilepsy, a common form of the neurological disorder.
Cardiac device trial highlights importance of female representation in research
A cardiac device trial published in eClinicalMedicine shows that improving enrollment of females in such trials can better guide care for all patients.
African swine fever vaccine shows variable protection across virus strains
An international team of scientists has found that a promising African swine fever (ASF) vaccine can protect pigs against some strains of the virus but offers little or no protection against others. The findings point to the need for region-specific vaccines to tackle one of the world's most devastating animal diseases.
Positive emotion bias in aging may signal cognitive decline
As people age, they display a bias in recognizing emotions as positive-to the point of improperly labeling neutral or negative emotions as positive.
Neural signature reveals how self-preoccupation manifests in the brain
People tend to be self-preoccupied. Self-interest is good when it ensures that one's needs are met, but it can also be maladaptive; research shows that the tendency to self-focus promotes the occurrence of depression and anxiety and can even prolong these conditions.
Scientists discover molecular brake that halts brain cell repair in multiple sclerosis
A team of scientists led by the Institute for Glial Sciences (IGS) at Case Western Reserve University's School of Medicine has discovered a built-in "brake" that controls when key brain cells mature.
Researchers discover why smoking tobacco helps people with ulcerative colitis
Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered why smoking tobacco helps people suffering from ulcerative colitis, a chronic disease typified by inflammation of the large intestine.
New insights into bone remodeling process in orthodontic tooth movement under hypoxia
Sustained hypoxia affects orthodontic tooth movement (OTM) by altering osteoclast and osteoblast differentiation, report researchers from Institute of Science Tokyo, Japan.
Food choices may depend more on blood sugar than body weight
Maybe you shouldn't always listen to your gut. Researchers at the Fralin Biomedical Research Institute at VTC recently studied flavor-nutrient learning - how people come to prefer certain food based on how it makes them feel.
Many advanced cancer patients receive treatments that conflict with their care goals
New research indicates that many patients with advanced cancer report receiving treatment focusing on longevity over comfort, even when their goal is the opposite.
Children in low-opportunity neighborhoods face much higher risk of gun injuries
Children residing in "very low-opportunity" neighborhoods are up to 20 times more likely to be hospitalized for gun injuries than those living in the most advantaged areas, reports a new multi-state study published in Pediatrics.
Excess deaths in Maui highlight hidden impact of wildfires
New research unveils the true death toll of the deadly August 2023 wildfires which took place in Lāhainā, Maui, Hawaiʻi - and which temporarily made wildfire a leading cause of death in Maui.
Gut bacteria provide key to identifying colorectal cancer from stool samples
Colorectal cancer is the second leading cause of cancer death worldwide. If detected early, it can be efficiently treated, but the cost and discomfort of colonoscopies - the main diagnostic method currently in use - often result in delayed diagnosis.
Genetic testing of IVF-created embryos could help more women over 35 have a baby sooner
Genetic testing of IVF-created embryos could help more women over 35 have a baby in less time, a clinical trial by researchers from King's College London, King's College Hospital, and King's Fertility has found.
New molecular mechanism offers hope for treating depression in the elderly
Major depressive disorder (MDD) is one of the most common psychiatric illnesses worldwide, but its molecular causes have still not been clearly identified.
Shame linked to lower quality of life in people with gut disorders
Feelings of shame are linked to reduced quality of life - as shown by the first study to measure shame as a factor influencing the connection between chronic gastrointestinal disorders and mental health.
Mind wandering may hold key to better ADHD diagnosis in adults
Only a few decades ago, it was believed that ADHD was something one outgrew during adolescence. However, about half of those diagnosed at a young age carry it into adulthood.