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Discovery could pave the way for new generation of RNA-based cancer treatments
Researchers fhave created a new type of drug molecule that can precisely destroy TERRA, an RNA molecule that helps certain cancer cells survive.
Common chemical tetrachloroethylene may be harmful to the liver
Liver disease is usually caused by one of three factors: alcohol consumption, fat buildup in the liver linked to obesity, diabetes and high cholesterol, or hepatitis B and C.
Impaired movement of cerebrospinal fluid predicts dementia risk later in life
Problems with the brain's waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the risk of dementia.
Psoriasis-linked gene mutation may also play a surprising role in gut health
A mutation previously linked to skin disorders like psoriasis may also play a surprising role in gut health, according to new research published by scientists at VIB-UGent and colleagues from UGent, the University of Barcelona, and University College London.
Restricted sugar intake during early life associated with lower cardiovascular risks in adulthood
Restricted sugar intake during early life is linked to lower risks of several heart conditions in adulthood, including heart attack, heart failure, and stroke, finds a study published by The BMJ today using data from the end of UK sugar rationing in 1953.
Semaglutide can offer important heart benefits that go beyond weight loss
A new analysis of the SELECT trial – the largest and longest clinical trial to date examining the cardiovascular benefits of semaglutide (a medication used to support weight loss and diabetes management) – confirms it also lowers the risk of major heart problems in people who are overweight or obese and already have heart disease, even if they don't have diabetes.
Disruption of glial circadian rhythms linked to Alzheimer's disease progression
Alzheimer's disease is notorious for scrambling patients' daily rhythms. Restless nights with little sleep and increased napping during the day are early indicators of disease onset, while sundowning, or confusion later in the day, is typical for later stages of the disease.
Drug shows striking success in treating children with multi-metastatic Ewing sarcoma
Ewing sarcoma is one of the most common bone cancers seen in children, and if it spreads, it can be deadly. One study found that under a quarter of children with multi-metastatic Ewing sarcoma survived five years after their diagnosis.
Physically fit individuals may better cope with dehydration stress
Individuals who are physically fit may be better equipped to handle the negative effects of dehydration, according to research from the University of California, Riverside. In a study using selectively bred "high-runner" mice, the scientists found that fitter animals increased their voluntary running activity when deprived of water - a finding that could have implications for human performance and health under environmental stress.
Novel PET scan quickly predicts functional recovery after heart attack
A new approach to PET imaging offers a promising way for physicians to promptly identify patients who are at risk for poor functional recovery after a heart attack, according to new research published in The Journal of Nuclear Medicine.
Novel molecule found to be a key player in kidney injury and repair
Chronic kidney disease (CKD) is a progressive condition in which the kidneys gradually lose their ability to filter waste from the blood.
How psychedelics profoundly reshape the perception of time and consciousness
A perspective article published in Psychedelics by Prof. Xiaohui Wang and colleagues examines how psychedelic substances profoundly reshape the perception of time, offering unprecedented insights into consciousness and potential therapeutic applications.
New guidelines aid parents and clinicians in pediatric tracheotomy decisions
The emotional strain on parents and other caregivers faced with deciding whether a tracheotomy is the best treatment for their child is hard to measure. The latest clinical practice guideline from the American Thoracic Society aims to give clinicians and parents/caregivers a way forward so they can navigate difficult decisions to ensure better outcomes for young patients. The guideline was published early online today, Wednesday, Oct. 22, in the American Journal of Respiratory and Critical Care Medicine.
Intensive program leads to high type 2 diabetes remission in India
Nearly one-third of people with type 2 diabetes (T2D) in an Indian cohort achieved remission through an intensive lifestyle intervention program, according to a new study publishing October 22, 2025, in the open-access journal PLOS One by Pramod Tripathi of Freedom from Diabetes Clinic & Diabetes Research Foundation, India, and colleagues.
Gender disparity in lung transplant access persists despite reforms
New research from UCLA Health reveals that women continue to face barriers in accessing lung transplants compared to men, despite recent national policy changes aimed at making organ distribution more equitable.
Study: Common test to assess viability of IVF embryos may be flawed
A test deployed in many fertility clinics to assess the viability of embryos for use in IVF is likely to overestimate the number of embryos with abnormalities, suggests a study published today.
Can introducing peanuts early prevent allergies? Real-world data confirms it helps
Using data from over 120,000 U.S. children, this Pediatrics study found that the prevalence and risk of peanut and other IgE-mediated food allergies declined significantly after the 2015 and 2017 guidelines promoting early allergen introduction. The findings support these policies as effective public health measures to prevent food allergies in real-world settings.
Scientists identify Bidara leaf extracts as the most effective natural antimicrobial source
Researchers tested methanolic extracts from the leaves, bark, roots, stems, and fruits of Ziziphus mauritiana (Bidara) and found the leaves had the strongest antibacterial and antifungal effects. The study highlights the plant’s antimicrobial potential while emphasizing the need for further bioactive compound identification and toxicity testing.
AI-driven eye screening aims to close the diabetic vision gap in community clinics
A new trial will evaluate whether integrating autonomous AI screening for diabetic retinopathy into U.S. federally qualified health centers can boost screening completion and accelerate early detection. The DRES-POCAI protocol tests a real-world, point-of-care model that links FDA-cleared AI with electronic health records to close gaps in diabetes eye care.
Mediterranean diet linked to dramatically lower odds of endometriosis
A new case–control study found that women with stronger adherence to the Mediterranean diet had dramatically lower odds of endometriosis. Diets rich in fruits, vegetables, fish, and legumes were protective, while higher intakes of meat, dairy, and refined whole grains were linked to increased risk.




