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Regular sleep schedule linked to better outcomes after heart failure
People recovering from heart failure should consider improving the regularity of their sleep, a study led by Oregon Health & Science University suggests.
Hypothalamic neurons help maintain blood sugar during daily activities
The brain controls the release of glucose in a wide range of stressful circumstances, including fasting and low blood sugar levels.
Neuroscientists split on whether memories can be extracted from preserved brains
A new survey of 312 neuroscientists reveals strong support for synaptic connectivity as the basis of long-term memory, but deep divides remain over memory extraction and brain emulation feasibility. The findings highlight both emerging consensus and sharp uncertainty in how memories are physically stored.
Seattle’s Fresh Bucks program boosts food security and diet but benefits fade when funding ends
A lottery-based cohort study of Seattle’s Fresh Bucks program found that providing a $40 monthly fruit and vegetable benefit improved food security by 5.5 percentage points and increased daily produce consumption by 7.5 percentage points, while disenrollment reversed these gains. These findings highlight the potential of healthy food benefit programs to reduce nutrition-related disparities in low-income populations.
Gut bacteria and insomnia influence each other in small but significant ways, study shows
Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.
Evidence review questions ketamine’s role in chronic pain treatment
A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.
Can AI help you eat healthier?
Researchers developed and validated an AI-based nutrition recommendation system (AINR) that generates weekly Mediterranean meal plans tailored to individual needs and dietary restrictions. Tested on 4,000 simulated users, the system achieved high accuracy in calorie and nutrient targets but struggled with profiles involving milk and nut allergies.
COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?
Researchers show that countries with higher initial COVID-19 vaccine acceptance also achieved stronger booster uptake, but trust and access remain decisive. The commentary warns that vaccine successes also fueled hesitancy, demanding structural reforms, clear communication, and proactive strategies to protect immunization.
Gut bacteria in mothers and newborns may shape infants’ risk of early respiratory infections
Finnish researchers found that differences in maternal and infant gut microbiota during the first weeks of life were linked to the risk of respiratory tract infections in the first six months. Specific bacteria, including butyrate producers and opportunistic pathogens, may shape early infection susceptibility.
New study uncovers a surprising mechanism of resistance to immunotherapy
A new international study led by researchers at Moffitt Cancer Center, the Karolinska Institutet and the University of Texas MD Anderson Cancer Center has uncovered a surprising mechanism of resistance to immunotherapy: cancer's ability to injure nearby nerves.
Study reveals how SARS-CoV-2 hijacks testicular lipid metabolism to replicate
The COVID-19 virus hijacks the machinery of testicular cells that produce the hormone testosterone in order to replicate.
Research shows how lysosomes respond to stress
New research, published today in the journal Science, shows how lysosomes - organelles that act like cells' waste disposal system - respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated with numerous diseases.
Early infection traits help predict future disease spread
When a disease-causing virus or other organism is transmitted from one species to another, most of the time the infection sputters and dies out.
Midkine found to prevent Alzheimer’s-related protein assemblies
Scientists at St. Jude Children's Research Hospital demonstrated for the first time that the protein midkine plays a preventative role against Alzheimer's disease.
Less education associated with faster aging and health inequality
A new study by USC Leonard Davis School of Gerontology researchers shows that Americans with less education are aging faster than their peers with more schooling, and the gap has grown over the last 30 years.
Physical forces play key role in shaping developing organs
A new study looks at the physical forces that help shape developing organs. Scientists in the past believed that the fast-acting biochemistry of genes and proteins is responsible for directing this choreography.
Computational approach provides insight into neural progenitor cells and their role in brain disorders
For much of the 20th century it was thought that the adult brain was incapable of regeneration. This view has since shifted dramatically and neurogenesis – the birth of new neurons – is now a widely accepted phenomenon in the adult brain, offering promising avenues for treating many neurological conditions.
Virus inside the fungus drives deadly fungal infections
Researchers have discovered that a virus living inside the fungus Aspergillus fumigatus significantly boosts the fungus's ability to survive stress and cause severe infections in mammals.
Breakthroughs in diagnosis and therapy for transthyretin amyloidosis
Transthyretin amyloidosis (ATTR) is caused by the misfolding and aggregation of the transthyretin (TTR) protein, leading to multi-organ damage.
New formulation of chemotherapy drug opens doors to advanced cancer treatment options
University of Arizona researchers devised a new method to deliver cancer chemotherapy drugs to pancreatic and breast cancer tumors more effectively and with less damage to healthy tissues than standard forms of chemotherapy.