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Study identifies why stroke impairs ability to use word meanings in reading
A key discovery about the impact of stroke on a person's ability to read reveals why a deficit occurs – a finding that presents a possible opportunity for new therapeutic strategies to help people recover one of the most important life skills.
Microbes found to play a key role in shaping early brain development
New research from Michigan State University finds that microbes play an important role in shaping early brain development, specifically in a key brain region that controls stress, social behavior, and vital body functions.
High-dose vitamin D in pregnancy likely cuts childhood wheeze risk, but infant supplements fall short
A Cochrane review of 18 randomized trials found that high-dose vitamin D during pregnancy likely reduces the risk of childhood wheeze, a key early symptom of asthma. However, vitamin D supplementation in infants and young children showed uncertain benefits for asthma prevention.
Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds
A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.
Pandemic left measurable changes in teen brains, hormones, and immunity
Adolescents assessed after COVID-19 lockdowns showed lower daily cortisol, higher inflammation, and reduced prefrontal cortex activity compared to matched pre-pandemic peers, suggesting widespread stress-related biological changes. These alterations mirror patterns seen after prolonged early-life stress, raising concerns about long-term health risks.
Curcumin activates SIRT3 to protect bone structure in diabetic mice
In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the SIRT3/FoxO3a/NRF2 antioxidant pathway and restoring mitochondrial health. In diabetic mice, curcumin improved bone density and oxidative balance, highlighting its potential in osteoporosis prevention.
Disrupting dopamine pathway stops threadworms from burrowing into the skin
Threadworms, which are a type of parasitic nematode, spend a lot of time crawling around on human skin, poking and prodding to find the best place for entry before burrowing in.
Clinicians more likely to express doubt in medical records of Black patients
Clinicians are more likely to indicate doubt or disbelief in the medical records of Black patients than in those of White patients-a pattern that could contribute to ongoing racial disparities in healthcare.
New research sheds light on what makes the human brain unique
Research from scientists at University of California San Diego School of Medicine have shed new light on an age-old question: what makes the human brain unique?
Extreme heat and humidity greatly increase heart emergency risk
Extreme heat can be hard on your heart. As temperatures rise, the heart pumps faster to move blood toward the skin to cool the body.
New mouse model reveals key role of osteocytes in osteogenesis imperfecta
Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.
Leading organizations announce research initiative to uncover why ALS affects high-performing populations
Answer ALS, in collaboration with ALS Therapy Development Institute (ALS TDI) and Augie's Quest, today announced plans to launch Champion Insights, an ambitious research initiative designed to uncover critical genetic and metabolic mechanisms that may explain the significantly higher incidence of amyotrophic lateral sclerosis (ALS) among endurance athletes, military service members, and potentially other high-performing populations.
Primary care could help meet growing needs of cancer survivors
Thanks to new advances in cancer care, more and more people are surviving cancer, with a projected total of 22.5 million survivors by 2032.
Low screening rates linked to higher cervical cancer deaths in rural counties
Women in counties with repeatedly lower cervical cancer screening rates suffer nearly double the rate of cervical cancer diagnoses, particularly of late-stage disease, and death from cervical cancer, according to a new analysis from researchers at MUSC Hollings Cancer Center.
Study identifies a promising new strategy for treating alcohol use disorder
Researchers have identified a promising new strategy for treating alcohol use disorder (AUD). A novel study found that the dopamine-boosting drug tolcapone increases activity in the prefrontal cortex (PFC) during self-control tasks.
Quitting smoking linked to better recovery from drug and alcohol addiction
Adults who smoke cigarettes and are addicted to alcohol or other drugs were more likely to achieve sustained remission of their substance use disorder symptoms if they also quit smoking, according to scientists at the National Institutes of Health (NIH). `
Understanding opioid safety and overdose prevention for older adults
With increasing age, older adults are more likely to encounter health conditions and injuries that require opioid therapy for pain relief.
New compound shows promise against aromatase inhibitor-resistant breast cancer
A new research paper was published in Volume 16 of Oncotarget on July 29, 2025, titled "PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion."
Lifestyle choices and irregular sleep patterns drive weekend spike in OSA severity
Late nights, alcohol, and smoking on weekends may be doing more than disrupting your Monday mornings, they could be triggering a newly identified sleep health concern known as 'social apnea', warn researchers from Flinders University.
Research explores connection between reading imagination and mental health
A new tool to understand how people imagine differently when reading could have potential implications for the treatment of mental ill health.