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Breast cancer maintains its position as the most prevalent malignancy in women worldwide, with triple-negative breast cancer (TNBC) representing the most treatment-resistant subtype due to limited therapeutic targets and frequent relapse.

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications.

Researchers at Columbia Engineering have built a cancer therapy that makes bacteria and viruses work as a team.

Platelets are probably best known for their role in blood clotting, making scabs and related, if less salubrious, contributions to heart attacks and strokes. But these tiny, saucer-shaped blood cells have other physiological duties as well, including surveillance for viral or bacterial infections, the recruitment of immune cells to the site of a suspected incursion, and even the direct destruction of pathogens.

New research to be presented at the 2025 Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (September 15-19, 2025) shows that early detection of individuals at risk for diabetes is possible by analyzing the electronic records of people living within the same household for risk factors. The study is led by Dr Tainayah Thomas, Stanford University, Palo Alto, CA, USA, and colleagues.

Acute kidney injury (AKI) is a severe renal disorder affecting approximately 10%-15% of hospitalized patients and up to 50% in intensive care units (ICUs). Its pathogenesis involves complex inflammatory regulatory mechanisms. As core components of the cytokine network, interleukins (ILs) exert pleiotropic effects in AKI development, extensively participating in inflammation, fibrosis, tissue injury repair, and remote organ damage.

A Covid infection, particularly in women, may lead to blood vessels aging around five years, according to research published in the European Heart Journal on 18th August, 2025.

Neovascular age-related macular degeneration (nAMD) is a progressive eye disease characterized by choroidal neovascularization and subretinal hemorrhage and exudation, leading to vision impairment. Current first-line treatment for nAMD are anti-VEGF agents, which has shown promising therapeutics outcomes.

The off-label use of ketamine to treat chronic pain is not supported by scientific evidence, a new Cochrane review has found.

Curcumin/turmeric supplements modestly reduced body weight, waist size, fat mass, and hip circumference in people with type 2 diabetes. Benefits were also seen in prediabetic individuals, especially with longer use and high-absorption formulations.

A new systematic review of five meta-analyses confirms that ginger significantly reduces inflammation, lowers blood sugar and HbA1c in type 2 diabetes, and improves antioxidant status. It also effectively reduces nausea in pregnancy, though its impact on vomiting is less consistent.

The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor and immune cells vie for limited resources.

Tumor electrophysiological abnormalities, characterized by membrane potential dysregulation, ion channel network remodeling, and microenvironmental signaling interactions, are critical drivers of malignancy.

New research from the Charles Perkins Centre at the University of Sydney has uncovered a new biological pathway that may help explain why people with type 2 diabetes are more prone to developing dangerous blood clots, potentially paving the way for future treatments that reduce their cardiovascular risk.

Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives.

One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy-and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this.

Neurons in the gut produce a molecule that plays a pivotal role in shaping the gut's immune response during and after inflammation, according to a new study by Weill Cornell Medicine investigators.

A multi-institutional team led by Weill Cornell Medicine has received a five-year, $14.9 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find ways to remove latent HIV from the cells of individuals with HIV.

It has long been understood that experiencing two senses simultaneously, like seeing and hearing, can lead to improved responses relative to those seen when only one sensory input is experienced by itself.

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.