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To our immune system, naked RNA is a sign of a viral or bacterial invasion and must be attacked. But our own cells also have RNA.

A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression of cdc42 activity could be a promising therapy for nephrotic syndrome.

Up to 60% of women experience some fear about giving birth, especially for the first time, but a new study shows why some women are more likely to stay calm and confident in the lead-up to childbirth.

COVID-19 prevention methods such as masking and social distancing also suppressed the circulation of common respiratory diseases, leaving young children lacking immunity to pathogens they otherwise would have been exposed to, a new multi-center clinical research study reveals.

A Mediterranean diet during pregnancy significantly alters the maternal gut microbiome, increasing beneficial bacteria, while a mindfulness-based stress reduction program shows more limited effects. Neither intervention affected the vaginal microbiome, and the clinical significance of these changes requires further study.

A latest systematic review and meta-analysis conducted by scientists from institutions across China and the United States has uncovered promising insights into how vitamin D supplementation can significantly impact cardiometabolic health.

In a pair of new studies, researchers found that older adults who challenge themselves to learn new things are less likely to experience loneliness or depression, even during times of major upheaval.

Red blood cells, long thought to be passive bystanders in the formation of blood clots, actually play an active role in helping clots contract, according to a new study from researchers at the University of Pennsylvania.

In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against Alzheimer's disease.

Analysis of over 36,000 people with high blood pressure has shown that taking more steps, even below the recommended daily target of 10,000 steps, and walking faster, is associated with a significant reduction in the risk of major problems of the heart and blood vessels.

Researchers established a high-quality genetic dataset from the MIND diet trial, enabling new studies of gene–diet interactions in cognitive health. This resource allows deeper investigation into why individuals respond differently to dietary interventions targeting dementia risk.

Experiencing complications during pregnancy is linked with a higher risk of stroke before age 50, according to a study published August 6, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

Researchers identified specific flavonols that potently inhibit breast cancer resistance protein (BCRP), a key driver of drug resistance and poor oral drug absorption. The study found that these flavonols can reverse chemotherapy resistance in vitro and boost drug exposure in animal models, though clinical translation remains uncertain.

Caffeine consumption is linked to increased positive mood in daily life, especially within 2.5 hours after waking. This effect is influenced by tiredness and social context, with no consistent impact on negative emotions.

A large, multi-decade cohort study found that frequent French fry consumption raises type 2 diabetes risk, while baked, boiled, or mashed potatoes do not. Swapping any type of potato for whole grains, but not white rice, lowers diabetes risk.

Despite concerns about increased stimulant prescribing, nonmedical use of ADHD drugs among adolescents has declined in the last 20 years, a University of Michigan study shows.

Living with cardiovascular disease often takes a serious emotional toll - and with stress known to worsen heart health, there's growing interest in low-risk, innovative ways to help patients cope.

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

Researchers at the Francis Crick Institute have discovered that the heart's own contractions trigger biological signals that guide the formation of a functional beating heart.

Most patients with high-risk myelodysplastic syndromes (MDS) do not receive guideline-recommended treatment with hypomethylating agents (HMAs), according to results published in Blood Neoplasia.