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Air purifiers can lower blood pressure in at-risk adults
Using portable high-efficiency particulate air (HEPA) purifiers at home can significantly lower systolic blood pressure (SBP) in adults with elevated baseline readings — even in areas with relatively low overall air pollution levels, according to a study published today in JACC, the flagship journal of the American College of Cardiology.
Immune aging drives the progression of type 2 diabetes
Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure.
TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation
The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully-causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR).
Gut microbiota and short chain fatty acids influence bone health in postmenopausal osteoporosis
Postmenopausal osteoporosis (PMOP) is framed as a systemic bone disease driven by estrogen withdrawal, but emerging evidence positions gut dysbiosis and its fermentation products—short-chain fatty acids (SCFAs)—as equally influential regulators of skeletal fate.
Prime editing reverses symptoms of severe childhood neurological disease
Scientists use a precise form of gene editing called prime editing to correct the most common genetic mutations that cause alternating hemiplegia of childhood, a rare and severe neurological disorder that begins in infancy.
Study finds link between past life memories and mental health challenges
Researchers analyzed the profile of adults who claim to have past-life memories, the features of these memories, and their associations with mental health, happiness, and religiosity/spirituality.
Staying in hurricane affected zones linked to increased mortality in the elderly
Hurricanes and related natural catastrophes like flooding are becoming more severe and more frequent around the world. Older people are especially at risk, but relatively little is known about long-term health effects.
Diabetes drug linked to lower risks of dementia and early death
New research in Diabetes, Obesity and Metabolism reveals that metformin, a medication traditionally prescribed to treat diabetes, is linked to lower risks of dementia and early death.
Low oxygen environment protects brain and restores movement in mice with Parkinson's
Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment - similar to the thin air found at Mount Everest base camp - can protect the brain and restore movement in mice with Parkinson's-like disease.
Apple snail eye regeneration offers new insights into human sight restoration
The eye of the apple snail is unusually similar to a human eye-but, unlike human eyes, it can regrow itself if injured or even amputated.
Excessive screen time linked to higher cardiometabolic risk in youth
Children and young adults who spend excessive hours glued to screens and electronic devices may have higher risks for cardiometabolic diseases, such as high blood pressure, high cholesterol and insulin resistance, according to new research published today in the Journal of the American Heart Association, an open-access, peer-reviewed journal of the American Heart Association.
HOXB13 emerges as a context-dependent regulator in cancer biology
HOXB13, a B-class homeobox transcription factor, sits at the hub of developmental gene networks yet has emerged as a double-edged sword in human cancer.
Targeting lactate metabolism offers new avenues for cancer treatment
Lactic acid (LA) has transitioned from being perceived as a mere glycolytic waste product to a pivotal regulator of tumor-immune crosstalk.
Researchers question the historical basis of ancient psychedelic rituals
A new article in the peer-reviewed journal Psychedelic Medicine takes aim at one of the most influential, and controversial, narratives in comparative psychedelic culture: the idea that ancient Greek mystery rites at Eleusis were fueled by psychedelic drugs.
Solastalgia identified as key concept linking climate change to mental health
'Solastalgia' might help explain the negative effects of climate change on mental health, suggests a review of the available research, published in the open access journal BMJ Mental Health.
Australian study finds lasting relief for back pain through cognitive functional therapy
Australian research has shown that a personalized program that helps people with chronic, disabling low back pain better understand their condition and take charge of its management produces large benefits that are sustained over three years.
Mother’s genetics may play an important role in influencing her child's weight
A mother's genetics may play a bigger role in determining whether a child becomes overweight than a father's, as a result of a concept known as genetic nurture, finds a new study led by UCL researchers.
Childhood verbal abuse has lasting mental health effects similar to physical abuse
Experiencing childhood verbal abuse shows a similar impact to adult mental health as physical abuse, suggests a large intergenerational study, published in the open access journal BMJ Open.
Hypoglossal nerve stimulator shows promise for treating sleep apnea in children with Down syndrome
Sleep apnea, or difficulty breathing at night, is common among children with Down syndrome-affecting up to 80% compared to just 5% of the general pediatric population.
UC Irvine researchers discover naturally occurring compounds to rejuvenate aging brain cells
Researchers at the University of California, Irvine have identified a promising nonpharmaceutical treatment that rejuvenates aging brain cells and clears away the buildup of harmful proteins associated with Alzheimer's disease.