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How too much screen time affects kids’ heart health and what can reduce the risk
A large Danish cohort study found that higher screen time in childhood and adolescence is linked to worse cardiometabolic health, with shorter sleep amplifying the risk. Blood metabolomics revealed a signature of high screen time, and in teens, it was tied to higher predicted cardiovascular disease risk.
Genetic testing can guide safer chemotherapy for gastrointestinal cancer patients
For some patients with gastrointestinal (GI) cancers like colorectal and pancreatic cancer, chemotherapy can cause severe, sometimes life-threatening side effects in those who carry certain genetic variants that can impact how their bodies process the drugs used to treat their disease.
Study sheds light on how early brain wiring lays the foundation for attention skills
A new study by researchers at Simon Fraser University is shedding light on how the brain's wiring in early childhood lays the foundation for attention skills- a key step toward characterizing healthy developmental patterns that could help identify young children at risk for attention-related challenges like ADHD.
Researchers uncover dozens of traits driven by maternal versus paternal genes
Researchers developed a high-accuracy method to infer whether genetic variants come from the mother or father without needing parental genomes, analysing 286,666 UK Biobank participants. They uncovered over 30 parent-of-origin effects on traits from growth and metabolism to diabetes, many showing opposite effects depending on parental source.
AI-powered sweat sensor predicts anxiety before symptoms appear
Researchers have developed Stressomic, a wearable microfluidic biosensor that sequentially measures cortisol, epinephrine, and norepinephrine in sweat at six-minute intervals. The device distinguishes physical from psychological stress and predicts anxiety levels using machine learning.
Scientists link brain lithium loss to early Alzheimer’s changes
Researchers have discovered that naturally occurring lithium in the brain is depleted early in Alzheimer’s disease, especially in the prefrontal cortex, and that restoring physiological levels with lithium orotate in mice can prevent brain damage and memory loss. The findings suggest lithium deficiency may be a modifiable risk factor for Alzheimer’s.
New antibody delivery system boosts Alzheimer's treatment in mice
A newly engineered antibody transport vehicle targeting the transferrin receptor enables enhanced delivery of anti-amyloid antibodies to the brains of mouse models of Alzheimer's disease, researchers report.
Asthma drug found to prevent food allergy reactions in mice
A drug already FDA-approved for asthma was found to nearly eliminate life-threatening allergic reactions to food allergens in mice - a breakthrough that could lead to new protection for millions of people living with food allergies, reports a new Northwestern Medicine study.
New clues to how food allergies trigger anaphylaxis
New research in mice reveals that food-induced anaphylaxis is driven by distinct immune pathways involving inflammatory lipids called leukotrienes.
Uncovering the science behind musical anhedonia
Ten years ago, researchers discovered a small group of people who derive no pleasure from music despite having normal hearing and the ability to enjoy other experiences or stimuli.
Personalizing endometrial cancer prevention through diet and lifestyle
This review synthesizes emerging evidence on modifiable risk factors for endometrial cancer (EC)-the sixth most common female malignancy globally-with rising incidence despite diagnostic advances.
DKK1 identified as key driver of immune resistance in bone metastases
Many major cancers, including those of the lung, breast and prostate gland, spread to the bones as they progress.
Immune surveillance in children sheds light on virus rebound after COVID
The first paper from a multi-year clinical research study has been published in The Lancet Infectious Diseases: Dynamics of Endemic Virus Re-emergence in Children in the USA Following the COVID-19 Pandemic (2022-2023): A Longitudinal Immunoepidemiologic Surveillance Study and demonstrates how the approach can improve modeling to better predict future outbreaks.
Exosomes play a dual role in cancer progression and immune regulation
Tiny extracellular vesicles known as exosomes are emerging as key regulators of the tumor microenvironment (TME), influencing how cancer progresses, spreads, and responds to treatment.
Early-onset pancreatic cancer patients benefit more from neoadjuvant chemotherapy and surgery
The incidence of early-onset pancreatic cancer (EOPC) is rising, yet optimal treatment strategies remain unclear.
Maple compound offers natural protection against cavities
A new study in the journal Microbiology Spectrum highlights the potential of using a natural compound from maple to combat the bacteria responsible for tooth decay: Streptococcus mutans.
Study links epigenetic markers to cardiovascular risk in type 2 diabetes
People with type 2 diabetes are up to four times more likely to have heart attacks, strokes, anginas and other coronary heart diseases than healthy people.
KAIST researchers link placental inflammation to childhood allergies
It is already well-known that when a mother experiences inflammation during pregnancy, her child is more likely to develop allergic diseases.
New study reveals gaps in research on environmental antibiotic resistance
Antibiotic resistance in the environment is a growing and largely overlooked crisis receiving inconsistent attention, that may very well have dire consequences for human health, according to a new study led by the University of Surrey.
LabConnect deploys Sapio LIMS across global operations
Sapio Sciences, the science-aware™ lab informatics platform, today announced the full deployment of Sapio LIMS at LabConnect.