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Study sheds light on molecular mechanisms of brain aging
Aging and neurodegeneration are both known to disrupt the production of functional proteins in cells – a process called "proteostasis," or protein homeostasis.
Chemotherapy treatment linked to lasting cognitive changes in rats
Researchers at The City College of New York have linked chemotherapy treatment to lasting cognitive changes in rats – potentially shading light, for the first time, on cognitive problems some cancer survivors experience long after treatment ends.
New molecular insights reveal why some bladder cancers resist chemotherapy
About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy.
Suboptimal child passenger safety practices persist despite guidelines
Despite national guidelines, state laws and known safety benefits of child passenger restraint systems (CRS), suboptimal practices were found in nearly 70% of children under 13 years old who were involved in car crashes with a fatality from 2011 to 2021, according to a study published in the journal Traffic Injury Prevention.
New research reveals why fiber-rich diets fuel you better than refined foods
This study quantifies how much energy the human body harvests from gut microbial fermentation of dietary fiber, integrating bacterial physiology, diet, and metagenomic data. Results reveal that dietary fiber, not microbiome composition, mainly determines the amount of short-chain fatty acids absorbed, impacting daily energy and metabolic health.
Virtual memory T cells provide nonspecific immunity for infants early in life
Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life.
Selective impairment of translation contributes to brain aging in killifish
Aging selectively impairs the production of crucial DNA- and RNA-binding proteins, which contributes to hallmarks of aging in the brains of killifish, according to a new study.
Behavioral adaptation precedes morphological change in human evolution
As early humans spread from lush African forests into grasslands, their need for ready sources of energy led them to develop a taste for grassy plants, especially grains and the starchy plant tissue hidden underground.
Understanding how the brain distinguishes between stuff and things
Imagine a ball bouncing down a flight of stairs. Now think about a cascade of water flowing down those same stairs.
Advancing osteochondral regeneration through biomaterial-based drug delivery systems
Announcing a new article publication for BIO Integration journal. Osteochondral damage is primarily caused by degeneration of articular cartilage due to trauma, degenerative injury.
Immunoglobulin replacement therapy not associated with reduced risk of serious infections in patients with CLL
In patients with chronic lymphocytic leukemia (CLL), regular treatment with immunoglobulin replacement therapy was not associated with a reduced risk of serious infections requiring hospitalization, according to a study published in Blood Advances.
$29 million grant funds research on fibrinogen in trauma care
The University of Colorado Anschutz Medical Campus will lead a groundbreaking national clinical trial-supported by a $29 million grant from Octapharma-to evaluate whether early replacement of fibrinogen, a critical blood clotting mechanism in the body, can improve outcomes for trauma patients experiencing life-threatening bleeding.
UCSF research maps over 600 conditions linked to endometriosis
Records from millions of patients at UC health centers found correlations between endometriosis, one of the most common diseases in women, and a bounty of other diseases.
Rethinking prostate cancer risk in GG1 diagnoses
A new study reveals that some men who are diagnosed with "Grade Group one" (GG1) prostate cancer may actually be at higher risk than biopsy results suggest, according to research led by Weill Cornell Medicine, University Hospitals Cleveland and Case Western University.
Gut bacteria produce hormone-like proteins that regulate weight and blood sugar
Our intestines are home to trillions of microorganisms that produce substances capable of regulating all the body's organs via the bloodstream and the gut's nervous system.
New treatment shows promise in protecting brain following stroke reperfusion
Cambridge scientists have developed and tested a new drug in mice that has the potential to reduce damage to the brain when blood flow is restored following a stroke.
Powerful bioactives found in overlooked Amazonian fruits
Lesser-known Amazonian fruits exhibit strong antioxidant and antimicrobial properties, highlighting their role in public health and biotechnology research.
Women who drink heavily face higher chance of unintended pregnancy
A new study has found that, among women with a high desire to avoid becoming pregnant, those who drank heavily had a 50% higher risk of becoming pregnant than those who drank moderately or not at all.
Flooding linked to increased hospitalizations among older adults
New research examining 17 years of data from Medicare hospitalization claims and major flooding events finds increased rates of skin diseases, nervous system diseases, and injuries or poisonings among adults aged 65 and older following major floods.
$5.5 million federal grant funds research to improve measurement of FXTAS treatments
UC Davis Health Professor of Psychiatry and Behavioral Sciences David Hessl will help lead a major research project to develop better ways to measure treatments for fragile X-associated tremor/ataxia syndrome (FXTAS).