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The powerful role of exercise in maintaining skeletal muscle could be the key to improving health and resilience in older age, according to new research from Monash University.

A new study by investigators from Mass General Brigham Cancer Institute found that an ultrasensitive blood test called HPV-DeepSeek could help identify which people with HPV-associated head and neck cancer still had cancer cells in their bodies after surgery and may benefit the most from additional treatments. Their results are published in Science Translational Medicine.

Researchers at RCSI University of Medicine and Health Sciences have developed an artificial model of the mitral heart valve that faithfully mimics the valve's complex mechanical behavior in the human heart.

A novel study among Indigenous communities in Canada utilizing sharing circles as the primary method of qualitative data collection shows that heart health is shaped by emotional, spiritual, social, and systemic factors, with trauma strongly influencing how care is accessed and trusted.

A research team in Japan has developed an efficient and minimally invasive cancer detection device that uses high-performance zinc oxide nanowires to selectively capture extracellular vesicles (EVs) from bodily fluids.

A US cause-specific modeling study found no net protective health effect from low-level alcohol consumption, with lifetime alcohol-attributable mortality risk rising above 1 in 1,000 at just over 6.5 drinks per week for males and 7.0 drinks per week for females.

Researchers found that KAT7 promotes CMPK2-driven mitochondrial DNA release in microglia, activating inflammatory cGAS-STING and NLRP3 pathways linked to Alzheimer’s disease.

The cGAS-STING pathway is emerging as a key driver of chronic neuroinflammation through its effects on glial activation, neuronal stress, blood-brain barrier integrity, and type I interferon signaling. The review highlights why selective, context-dependent modulation of cGAS-STING could help treat neurodegenerative diseases, while preserving its essential roles in antiviral defense and tumor surveillance.

A JCI study found that exposure to a Western diet in mice and to palmitic acid in murine and ex vivo human enteric nervous system models triggered ferroptosis, characterized by iron loading, lipid peroxidation, mitochondrial stress, and enteric neuronal loss. Boosting Nrf2 signaling protected enteric neurons and prevented Western diet-induced delayed colonic transit in mice, pointing to a potential pathway linking dietary fat exposure to gut motility dysfunction.

An unexpected lab observation led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer.

A new report in the American Journal of Human Genetics describes a novel disorder caused by biallelic loss-of-function variants in the TMEM63B gene, which results in severe lung disease.

Sjögren's disease is a widespread chronic autoimmune disorder that attacks the body's own glands, yet its underlying disease mechanisms remain poorly understood.

Fewer than one in four people with stroke and fewer than one in seven people with traumatic brain injury receive inpatient rehabilitation care after being hospitalized, according to a study published on June 10, 2026, in Neurology Open Access, an official journal of the American Academy of Neurology.

For people with physical frailty, having high blood pressure may be associated with a lower risk of dementia, according to a study published on June 10, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

​Researchers at the Nuffield Department of Medicine, University of Oxford, together with Newcastle University's Translational and Clinical Research Institute and the Department of Immunology at Cambridge University Hospitals NHS Foundation Trust, have identified an important driver of inflammatory bowel disease (IBD).

Women who engage in light physical activity and lessen their sedentary time may significantly reduce the risk of key health problems during pregnancy, according to a new University of Iowa-led study.

People who follow a short-term low-calorie diet may have reduced markers of inflammation associated with gum disease.

Researchers found that workers in remote jobs spent more time alone after the COVID-19 pandemic and experienced greater psychological distress than those in non-remote jobs. The effects were strongest among people living alone, suggesting that reduced everyday social contact may be an important cost of remote work.

DNA is composed of long chains that act as the blueprint for living organisms. In genetic engineering, scientists cut DNA at specific sites and join the resulting fragments to other DNA sequences, enabling applications such as advanced crop breeding, genetic disease treatment, and the generation of animal models for drug discovery.

A study of 2,044 older Japanese adults found that those with lower vitamin C levels in their blood plasma tended to have a lower volume of gray matter in their brains, as well as lower connectivity amongst a collection of brain regions known as the default mode network.