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Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

A healthy diet in early pregnancy supports the child's motor development at the age of 5-6 years. Higher maternal body fat mass, on the other hand, has an adverse effect on the child's motor development.

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.

Research reveals why misplaced neurons in the brain are overactive and lead to developmental disorders.

Early diagnosis of lung cancer is a critical priority in clinical practice. It may help reduce the rate of lung-cancer-related mortality, extend disease-free survival, and allow patients to live without ongoing medical interventions and complications.

A newly published review in Genes & Diseases explores the oncogenic activation of PIK3CA in cancer and highlights emerging targeted therapies designed to improve treatment efficacy while reducing side effects.

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its potential as a therapeutic target.

A new study published this week in Archives of Gerontology and Geriatrics Plus found that 10% of South Asian immigrants aged 45 and older in Canada had hypothyroidism.

Integrating routine psychological health screening and treatment during and after pregnancy may reduce the risk of adverse pregnancy outcomes and improve maternal cardiovascular health, according to a new scientific statement published today in a Go Red for Women spotlight issue of the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

New research from Emory University indicates that childhood trauma physically alters the hearts of Black women.

In a peer-reviewed Perspective (review) article, researchers at the University of Nebraska Medical Center have uncovered concerning evidence that commonly prescribed medications may interfere with crucial brain development processes by disrupting sterol biosynthesis.

Blue-enriched light can improve sleep quality and daily activity in older adults living at home, according to new research from the University of Surrey.

Vitamin D supplementation shows no significant effect on acute respiratory infections overall, but children and daily low doses may offer protective benefits.

Researchers examine the association between excessive screen time and manic symptoms in early adolescence.

Researchers explore how artificial intelligence is transforming infectious disease modeling

Psychological factors have a greater impact on the severity of symptoms in esophageal diseases than objective evaluations, such as acid reflux and esophageal motility function. Although there are questionnaires that assess general psychological states in Japan, there were none that were specific to esophageal symptoms.

A minimally invasive therapy that has the potential to transform treatment of a common cause of high blood pressure, has been developed by researchers at UCL, Queen Mary University of London and Barts Health.

New research suggests that antidepressants can accelerate cognitive decline in people with dementia. At the same time, some drugs appear to be less harmful than others, which can help doctors make better treatment decisions, according to the study published in BMC Medicine.

Diabetes and obesity have become pressing health issues worldwide. Glucagon-like peptide-1 (GLP-1) receptor agonists, a class of medications widely used in the treatment of type 2 diabetes (T2D), have shown significant effectiveness in both lowering blood sugar levels and aiding weight loss due to their unique pharmacological mechanisms.

Researchers provided genetic and meteorological evidence suggesting that windborne transmission of HPAI H5N1 over 8 km is possible, highlighting its role in poultry farm outbreaks.