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A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

Older people have greater general happiness, life satisfaction and sense of purpose than they did before the Covid-19 pandemic.

University of California, Merced's Nicotine and Cannabis Policy Center has embarked on an innovative partnership with researchers at the university who track an entire community's health and habits with samples of human sewage.

University of Queensland researchers have found smoking rates have declined twice as fast in New Zealand as in Australia, suggesting less restrictive regulation on vaping could improve public health outcomes.

Seeking to understand what constitutes a healthy vaginal microbiome, a global research collaboration that includes a Rutgers-New Brunswick scientist has reported a series of findings, including identifying which bacteria thwart vaginal disease and determining that microbiomes vary significantly across human populations.

Micro- and nanoscale plastic particles in soil and water can significantly increase how much toxic chemicals plants and human intestinal cells absorb, according to two new studies from Rutgers Health that raise fresh concerns about food safety from plastic pollution.

In a randomized clinical trial, researchers from Huntsman Cancer Institute at the University of Utah (the U) have found that short-course, higher dose vaginal brachytherapy for endometrial cancer had similar effectiveness to more frequent, lower dose sessions.

Scientists have developed new light-sensitive chemicals that can radically improve the treatment of aggressive cancers with minimal side effects.

A new study in an animal model provides direct evidence for the role of the vagus nerve in gut microbiome-brain communication, addressing a critical gap in the field.

For people living with Type 1 Diabetes (T1D), keeping blood sugar levels in check is a constant challenge.

New research shows that inhaling polluted air for just an hour can impair cognitive abilities like attention and emotional recognition within four hours, highlighting the urgent need for cleaner air policies.

A team of public health researchers found "very low-certainty evidence" to support a commonly held belief that nicotine vaping is a gateway to cigarette smoking for young people.

Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer immunotherapy, while penta-acylated LPS may suppress immune responses.

Broccoli sprout extract (BSE) modestly lowered fasting blood glucose in prediabetes, but its effectiveness depended on gut microbiota, particularly the BT2160 operon.

A groundbreaking study reveals how a rare combination of genetics, proteomics, and environmental factors may hold the key to delaying or preventing Alzheimer's, challenging long-held assumptions about the disease.

Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction without altering DNA, offering a potential one-time treatment for high cholesterol.

Newborns with heart complications can rely on their newly developed immune systems to regenerate cardiac tissues, but adults aren't so lucky.

Scientists from the German Cancer Research Center (DKFZ) and ShanghaiTech University have developed an innovative method for growing brain tumors of individual patients in the laboratory that mimic the original structure and the molecular property of the parental tumor as closely as possible.

A new research paper was published in Aging (Aging-US) on January 15, 2025, in Volume 17, Issue 1, titled "Association between physical activity practice and sleep quality of older people in social isolation during the COVID-19 pandemic and Health Guidelines and future studies for the post-COVID period: a systematic review."

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center and University of California San Diego Health. Clots are the second-leading cause of death among cancer patients with advanced disease or aggressive tumors.