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In a mouse model of acute ischemic stroke, researchers showed that inhibiting the aggregation of GAPDH, either genetically or with a novel peptide, significantly reduced brain damage and improved neurological function. The findings highlight GAPDH aggregation as a promising therapeutic target for stroke intervention.

Researchers found that Halicin, an AI-identified drug, effectively inhibited most multidrug-resistant bacteria except Pseudomonas aeruginosa. The study highlights Halicin’s broad-spectrum antibacterial potential and the transformative role of artificial intelligence in antibiotic discovery.

Economic development drives higher obesity rates worldwide, but not because people move less. Instead, rising consumption of ultraprocessed foods plays a much bigger role than declining physical activity in the global obesity crisis.

Researchers tested five Nigerian medicinal plants in female rats and found that these botanicals reversed MSG-induced hormonal imbalance, oxidative stress, and lipid disruptions linked to dysmenorrhea. The findings support further investigation of plant-based therapies for menstrual pain and related metabolic risks.

Researchers studying low-income children in upstate New York found three distinct snack and drink consumption patterns. However, none of these dietary patterns predicted early childhood caries, highlighting the complex, multifactorial origins of the condition.

Higher scores on a dietary index linked to gut microbiota health are associated with slower biological aging in US adults, according to a large cross-sectional NHANES study. The findings suggest that improving diet quality for gut microbial diversity may help reduce age-related disease risk.

A network meta-analysis of 35 RCTs found that mind-body training is the most effective exercise modality for reducing frailty and improving quality of life in older adults. Mind-body interventions outperformed aerobic, strength, and mixed training across diverse populations and settings.

Researchers identified that two cyclin D genes, ccndx and ccnd2a, independently regulate distinct stem and progenitor cell populations during zebrafish sensory organ regeneration. The findings reveal that regeneration can proceed via alternative pathways even when one gene is disrupted, providing new insight into tissue repair mechanisms.

Hypertensive disorders in pregnancy (HDP) - like chronic or gestational hypertension, preeclampsia, and eclampsia - are among the leading causes of maternal and infant death in the United States.

A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as genetic "junk", may actually play powerful roles in regulating gene expression.

Inhaling agricultural dust may pose significant risks to gut health for workers in animal agriculture, a University of California, Riverside, study has found.

A new study from Emory University reveals that maintaining optimal cardiovascular health can significantly improve overall physical and psychological well-being.

As youth engagement in high-energy sports surges, so does the prevalence of sport-related injuries. Among them, tibial tubercle avulsion fractures (TTAFs) represent a small but serious subset, accounting for less than 3% of pediatric fractures.

Nearly one-third of the nation's K-12 U.S. public schools mandate mental health screening for students, with most offering in-person treatment or referral to a community mental health professional if a student is identified as having depression or anxiety, according to a new study.

Vaccination of pregnant women has been linked to a drop in newborns being admitted to hospital with a serious lung infection, research suggests.

Ulcerative colitis (UC) causes misery for millions worldwide. It affects the large intestine, causing pain, cramping, and frequent bowel movements with bloody diarrhea.

Researchers have discovered an unusual case where two well-known cancer-related mutations-APC and KRAS-coexisted in a woman with familial adenomatous polyposis (FAP) and a history of endometrial cancer.

A new case report was published in Volume 12 of Oncoscience on July 2, 2025, titled "Navigating diagnostic complexity: A case report on uterine lipoleiomyoma, unveiling its benign nature amidst characteristics resembling liposarcoma."

Child physical abuse (CPA) is a leading cause of injury-related death among infants and young children. Common indicators include bruises, fractures, and particularly retinal and intracranial hemorrhages.

A research group in the Department of Pharmacology of the University of the Basque Country has investigated the adverse reactions that antipsychotics can cause in the mouth.